The Arizona Cardinals are 15-22 against the 49ers in the regular season and playoffs on the road all-time.
| TEAM | DATE | REC | TM | OPP | RESULT | W% | TD | 1DWN | OFF | OPP OFF | 3DWN% | 4DWN% | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | Cardinals | 11/18/1951 | 1-0 | @ | W 27-21 | 1.000 | 3 | 17 | 437 | 379 | ||||
| 2 | | Cardinals | 9/29/1957 | 1-0 | @ | W 20-10 | 1.000 | 2 | 22 | 346 | 324 | ||||
| 3 |  | Cardinals | 9/27/1964 | 1-0 | @ | W 23-13 | 1.000 | 2 | 22 | 296 | 235 | ||||
| 4 | | Cardinals | 9/22/1968 | 0-1 | @ | L 17-35 | .000 | 2 | 13 | 228 | 395 | ||||
| 5 | | Cardinals | 10/6/1974 | 1-0 | @ | W 34-9 | 1.000 | 4 | 21 | 407 | 306 | ||||
| 6 | | Cardinals | 11/12/1978 | 1-0 | @ | W 16-10 | 1.000 | 2 | 21 | 335 | 264 | ||||
| 7 | | Cardinals | 9/14/1980 | 0-1 | @ | L 21-24 | .000 | 3 | 21 | 342 | 392 | ||||
| 8 | | Cardinals | 11/9/1986 | 0-1 | @ | L 17-43 | .000 | 2 | 22 | 364 | 460 | ||||
| 9 | | Cardinals | 10/18/1987 | 0-1 | @ | L 28-34 | .000 | 4 | 18 | 324 | 448 | ||||
| 10 |  | Cardinals | 11/17/1991 | 0-1 | @ | L 10-14 | .000 | 1 | 13 | 176 | 257 | 20.0 | 0.0 | ||
| 11 | | Cardinals | 10/24/1993 | 0-1 | @ | L 14-28 | .000 | 2 | 25 | 429 | 428 | 58.8 | 66.7 | ||
| 12 |  | Cardinals | 10/1/2000 | 0-1 | @ | L 20-27 | .000 | 2 | 16 | 365 | 345 | 23.1 | 66.7 | ||
| 13 | | Cardinals | 10/27/2002 | 0-1 | @ | L 28-38 | .000 | 4 | 23 | 420 | 357 | 75.0 | 100.0 | ||
| 14 | | Cardinals | 12/7/2003 | 0-1 | @ | L 14-50 | .000 | 2 | 18 | 210 | 496 | 21.4 | 66.7 | ||
| 15 | | Cardinals | 10/10/2004 | 0-1 | @ | L 28-31 | .000 | 4 | 19 | 320 | 448 | 35.7 | 100.0 | ||
| 16 | | Cardinals | 12/4/2005 | 1-0 | @ | W 17-10 | 1.000 | 1 | 18 | 404 | 220 | 31.3 | 0.0 | ||
| 17 | | Cardinals | 12/24/2006 | 1-0 | @ | W 26-20 | 1.000 | 2 | 21 | 372 | 223 | 50.0 | 100.0 | ||
| 18 | | Cardinals | 9/10/2007 | 0-1 | @ | L 17-20 | .000 | 2 | 20 | 261 | 194 | 40.0 | |||
| 19 | | Cardinals | 9/7/2008 | 1-0 | @ | W 23-13 | 1.000 | 2 | 18 | 285 | 291 | 31.3 | 66.7 | ||
| 20 | | Cardinals | 12/14/2009 | 0-1 | @ | L 9-24 | .000 | 1 | 11 | 245 | 327 | 36.4 | 100.0 | ||
| 21 | | Cardinals | 1/2/2011 | 0-1 | @ | L 7-38 | .000 | 1 | 19 | 279 | 362 | 45.0 | 0.0 | ||
| 22 | | Cardinals | 11/20/2011 | 0-1 | @ | L 7-23 | .000 | 1 | 11 | 229 | 431 | 11.1 | 0.0 | ||
| 23 | | Cardinals | 12/30/2012 | 0-1 | @ | L 13-27 | .000 | 1 | 11 | 262 | 407 | 25.0 | 100.0 | ||
| 24 | | Cardinals | 10/13/2013 | 0-1 | @ | L 20-32 | .000 | 3 | 16 | 403 | 387 | 38.5 | 0.0 | ||
| 25 | | Cardinals | 12/28/2014 | 0-1 | @ | L 17-20 | .000 | 2 | 26 | 397 | 395 | 40.0 | |||
| Average | .405 | 2.4 | 19.0 | 325.8 | 357.5 | ||||||||||
| Total | 15-22 | .405 | 87 | 703 | 12,056 | 13,228 | |||||||||
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More Cardinals Stats
Team Leaders 
PASS
1,600
Brissett
RUSH
245
Love
REC
472
McBride
Team Rankings
PPG
20.3
26th
OPP PPG
29.7
32nd
RUSH YDS/G
96.0
23rd
PASS YDS/G
229.6
21st
Seahawks
Rams
DAL
KC
WAS
NFL 2026 Leaders
NFL 2026 Rankings
NFL Fantasy 2026
NFL 2026 Betting
NFL 2026 Standings
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
4 | 2 | 1 | .643 | |
3 | 4 | 0 | .429 | |
2 | 5 | 0 | .286 | |
1 | 4 | 1 | .250 | |
| NFC North | W | L | T | PCT |
6 | 0 | 0 | 1.000 | |
5 | 2 | 0 | .714 | |
4 | 2 | 0 | .667 | |
4 | 3 | 0 | .571 | |
| NFC South | W | L | T | PCT |
3 | 3 | 0 | .500 | |
3 | 4 | 0 | .429 | |
2 | 5 | 0 | .286 | |
2 | 5 | 0 | .286 | |
| NFC West | W | L | T | PCT |
6 | 1 | 0 | .857 | |
4 | 3 | 0 | .571 | |
3 | 4 | 0 | .429 | |
2 | 5 | 0 | .286 |
Giants
Eagles
Vikings
Bears
Lions
Packers
Panthers
Falcons
Buccaneers
Saints| AFC East | W | L | T | PCT |
|---|---|---|---|---|
5 | 1 | 0 | .833 | |
4 | 3 | 0 | .571 | |
2 | 5 | 0 | .286 | |
1 | 5 | 0 | .167 | |
| AFC North | W | L | T | PCT |
5 | 2 | 0 | .714 | |
5 | 2 | 0 | .714 | |
4 | 2 | 0 | .667 | |
4 | 3 | 0 | .571 | |
| AFC South | W | L | T | PCT |
4 | 2 | 0 | .667 | |
2 | 5 | 0 | .286 | |
2 | 5 | 0 | .286 | |
1 | 6 | 0 | .143 | |
| AFC West | W | L | T | PCT |
5 | 1 | 0 | .833 | |
5 | 2 | 0 | .714 | |
3 | 4 | 0 | .429 | |
0 | 6 | 0 | .000 |
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