Between July 4, 2016 and July 4, 2026, the Indianapolis Colts have their lowest point differential in a home game against the Jaguars on October 22, 2017, with a -27-point differential.
Interpreted as:
colts largest home loss in a regular-season game last 10 years| TEAM | DIFF | DATE | TM | OPP | RESULT | TD | 1DWN | OFF | OPP OFF | 3DWN% | 4DWN% | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | Colts | -27 | 10/22/2017 | vs | L 0-27 | 0 | 15 | 232 | 518 | 33.3 | 0.0 | ||
| 2 | | Colts | -21 | 12/22/2025 | vs | L 27-48 | 3 | 19 | 312 | 440 | 50.0 | 0.0 | ||
| 3 | | Colts | -21 | 11/24/2016 | vs | L 7-28 | 1 | 18 | 310 | 369 | 53.3 | 50.0 | ||
| 4 | | Colts | -19 | 11/29/2020 | vs | L 26-45 | 4 | 27 | 336 | 449 | 38.5 | 50.0 | ||
| 5 | | Colts | -18 | 11/24/2024 | vs | L 6-24 | 0 | 11 | 268 | 390 | 25.0 | 0.0 | ||
| 6 | | Colts | -17 | 12/26/2022 | vs | L 3-20 | 0 | 10 | 173 | 314 | 0.0 | 25.0 | ||
| 7 | | Colts | -16 | 10/30/2016 | vs | L 14-30 | 2 | 18 | 277 | 422 | 30.8 | 50.0 | ||
| 8 | | Colts | -14 | 11/8/2020 | vs | L 10-24 | 1 | 20 | 339 | 266 | 16.7 | 50.0 | ||
| 9 | | Colts | -14 | 12/1/2019 | vs | L 17-31 | 2 | 22 | 391 | 292 | 41.7 | |||
| 10 | | Colts | -12 | 9/12/2021 | vs | L 16-28 | 2 | 23 | 336 | 381 | 38.5 | 0.0 | ||
| 11 | | Colts | -12 | 12/14/2017 | vs | L 13-25 | 1 | 15 | 228 | 462 | 46.2 | 0.0 | ||
| 12 | | Colts | -11 | 10/29/2023 | vs | L 27-38 | 3 | 19 | 371 | 511 | 43.8 | 100.0 | ||
| 13 | | Colts | -11 | 9/9/2018 | vs | L 23-34 | 2 | 24 | 380 | 330 | 64.7 | |||
| 14 | | Colts | -10 | 11/10/2024 | vs | L 20-30 | 2 | 19 | 361 | 415 | 36.4 | 66.7 | ||
| 15 | | Colts | -10 | 9/10/2023 | vs | L 21-31 | 3 | 18 | 280 | 342 | 16.7 | 20.0 | ||
| 16 | | Colts | -7 | 11/28/2022 | vs | L 17-24 | 2 | 19 | 290 | 323 | 25.0 | 66.7 | ||
| 17 | | Colts | -7 | 10/2/2022 | vs | L 17-24 | 2 | 21 | 365 | 243 | 53.8 | |||
| 18 | | Colts | -7 | 11/28/2021 | vs | L 31-38 | 4 | 24 | 392 | 359 | 45.5 | 100.0 | ||
| 19 | | Colts | -7 | 9/29/2019 | vs | L 24-31 | 3 | 22 | 346 | 377 | 37.5 | 100.0 | ||
| 20 | | Colts | -6 | 12/28/2025 | vs | L 17-23 | 2 | 16 | 204 | 370 | 36.4 | 0.0 | ||
| 21 | | Colts | -6 | 10/1/2023 | vs | L 23-29 | 3 | 19 | 329 | 467 | 30.0 | 50.0 | ||
| 22 | | Colts | -5 | 12/11/2016 | vs | L 17-22 | 2 | 21 | 348 | 316 | 41.7 | 0.0 | ||
| 23 | | Colts | -4 | 11/30/2025 | vs | L 16-20 | 2 | 17 | 281 | 364 | 30.0 | 0.0 | ||
| 24 | | Colts | -4 | 1/6/2024 | vs | L 19-23 | 1 | 21 | 360 | 306 | 9.1 | 0.0 | ||
| 25 | | Colts | -4 | 11/10/2019 | vs | L 12-16 | 1 | 19 | 300 | 229 | 38.5 | 0.0 | ||
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More Colts Stats
Team Leaders 
PASS
3,101
Jones
RUSH
1,585
Taylor
REC
1,003
Pierce
Team Rankings
PPG
27.4
8th
OPP PPG
24.2
21st
RUSH YDS/G
118.1
17th
PASS YDS/G
240.3
8th
NFL 2025 Leaders
NFL 2025 Rankings
NFL Fantasy 2025
NFL 2025 Betting
NFL 2025 Standings
| AFC East | W | L | T | PCT |
|---|---|---|---|---|
 Patriots - y | 14 | 3 | 0 | .824 |
 Bills - w | 12 | 5 | 0 | .706 |
 Dolphins - e | 7 | 10 | 0 | .412 |
 Jets - e | 3 | 14 | 0 | .176 |
| AFC North | W | L | T | PCT |
 Steelers - y | 10 | 7 | 0 | .588 |
 Ravens - e | 8 | 9 | 0 | .471 |
 Bengals - e | 6 | 11 | 0 | .353 |
 Browns - e | 5 | 12 | 0 | .294 |
| AFC South | W | L | T | PCT |
 Jaguars - y | 13 | 4 | 0 | .765 |
 Texans - w | 12 | 5 | 0 | .706 |
 Colts - e | 8 | 9 | 0 | .471 |
 Titans - e | 3 | 14 | 0 | .176 |
| AFC West | W | L | T | PCT |
 Broncos - z* | 14 | 3 | 0 | .824 |
 Chargers - w | 11 | 6 | 0 | .647 |
 Chiefs - e | 6 | 11 | 0 | .353 |
 Raiders - e | 3 | 14 | 0 | .176 |
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
 Eagles - y | 11 | 6 | 0 | .647 |
 Cowboys - e | 7 | 9 | 1 | .441 |
 Commanders - e | 5 | 12 | 0 | .294 |
 Giants - e | 4 | 13 | 0 | .235 |
| NFC North | W | L | T | PCT |
 Bears - y | 11 | 6 | 0 | .647 |
 Packers - w | 9 | 7 | 1 | .559 |
 Vikings - e | 9 | 8 | 0 | .529 |
 Lions - e | 9 | 8 | 0 | .529 |
| NFC South | W | L | T | PCT |
 Panthers - y | 8 | 9 | 0 | .471 |
 Buccaneers - e | 8 | 9 | 0 | .471 |
 Falcons - e | 8 | 9 | 0 | .471 |
 Saints - e | 6 | 11 | 0 | .353 |
| NFC West | W | L | T | PCT |
 Seahawks - z* | 14 | 3 | 0 | .824 |
 Rams - w | 12 | 5 | 0 | .706 |
 49ers - w | 12 | 5 | 0 | .706 |
 Cardinals - e | 3 | 14 | 0 | .176 |