The Indianapolis Colts have a record of 51-21 against the AFC South in the regular-season and playoffs at home since 1984.
| TEAM | DATE | REC | TM | OPP | RESULT | W% | TD | 1DWN | OFF | OPP OFF | 3DWN% | 4DWN% | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | Colts | 11/3/2002 | 0-1 | vs | L 15-23 | .000 | 2 | 25 | 378 | 198 | 30.8 | 50.0 | ||
| 2 | | Colts | 12/1/2002 | 1-0 | vs | W 19-3 | 1.000 | 2 | 13 | 278 | 165 | 26.7 | |||
| 3 | | Colts | 12/29/2002 | 1-0 | vs | W 20-13 | 1.000 | 2 | 18 | 272 | 266 | 38.5 | 100.0 | ||
| 4 | | Colts | 9/14/2003 | 1-0 | vs | W 33-7 | 1.000 | 3 | 20 | 291 | 236 | 25.0 | 100.0 | ||
| 5 | | Colts | 9/21/2003 | 1-0 | vs | W 23-13 | 1.000 | 2 | 17 | 289 | 266 | 50.0 | |||
| 6 | | Colts | 10/26/2003 | 1-0 | vs | W 30-21 | 1.000 | 3 | 23 | 391 | 270 | 45.5 | |||
| 7 | | Colts | 10/24/2004 | 0-1 | vs | L 24-27 | .000 | 3 | 23 | 446 | 414 | 60.0 | |||
| 8 | | Colts | 11/14/2004 | 1-0 | vs | W 49-14 | 1.000 | 7 | 17 | 398 | 302 | 55.6 | |||
| 9 | | Colts | 12/5/2004 | 1-0 | vs | W 51-24 | 1.000 | 6 | 29 | 567 | 340 | 37.5 | |||
| 10 | | Colts | 9/18/2005 | 1-0 | vs | W 10-3 | 1.000 | 1 | 18 | 268 | 303 | 43.8 | |||
| 11 | | Colts | 11/13/2005 | 1-0 | vs | W 31-17 | 1.000 | 4 | 26 | 419 | 209 | 40.0 | |||
| 12 | | Colts | 12/4/2005 | 1-0 | vs | W 35-3 | 1.000 | 5 | 21 | 292 | 260 | 50.0 | 100.0 | ||
| 13 | | Colts | 9/17/2006 | 1-0 | vs | W 43-24 | 1.000 | 5 | 34 | 515 | 299 | 75.0 | |||
| 14 | | Colts | 9/24/2006 | 1-0 | vs | W 21-14 | 1.000 | 3 | 14 | 272 | 297 | 46.2 | |||
| 15 | | Colts | 10/8/2006 | 1-0 | vs | W 14-13 | 1.000 | 2 | 20 | 320 | 277 | 41.7 | |||
| 16 | | Colts | 12/2/2007 | 1-0 | vs | W 28-25 | 1.000 | 4 | 19 | 342 | 411 | 76.9 | |||
| 17 | | Colts | 12/23/2007 | 1-0 | vs | W 38-15 | 1.000 | 5 | 33 | 458 | 299 | 54.5 | 100.0 | ||
| 18 | | Colts | 12/30/2007 | 0-1 | vs | L 10-16 | .000 | 1 | 13 | 194 | 356 | 41.7 | 0.0 | ||
| 19 | | Colts | 9/21/2008 | 0-1 | vs | L 21-23 | .000 | 3 | 19 | 325 | 403 | 55.6 | 100.0 | ||
| 20 | | Colts | 11/16/2008 | 1-0 | vs | W 33-27 | 1.000 | 3 | 30 | 474 | 356 | 66.7 | |||
| 21 | | Colts | 12/28/2008 | 1-0 | vs | W 23-0 | 1.000 | 2 | 21 | 390 | 125 | 57.1 | |||
| 22 | | Colts | 9/13/2009 | 1-0 | vs | W 14-12 | 1.000 | 2 | 21 | 365 | 228 | 57.1 | 0.0 | ||
| 23 | | Colts | 11/8/2009 | 1-0 | vs | W 20-17 | 1.000 | 2 | 27 | 378 | 382 | 50.0 | 0.0 | ||
| 24 | | Colts | 12/6/2009 | 1-0 | vs | W 27-17 | 1.000 | 3 | 23 | 358 | 375 | 64.3 | |||
| 25 | | Colts | 11/1/2010 | 1-0 | vs | W 30-17 | 1.000 | 3 | 24 | 366 | 291 | 46.7 | 100.0 | ||
| Average | .708 | 2.9 | 21.0 | 350.3 | 322.0 | 43.6 | 0.0 | ||||||||
| Total | 51-21 | .708 | 207 | 1,513 | 25,225 | 23,187 | 43.6 | 45.3 | |||||||
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More Colts Stats
Team Leaders 
PASS
3,101
Jones
RUSH
1,585
Taylor
REC
1,003
Pierce
Team Rankings
PPG
27.4
8th
OPP PPG
24.2
21st
RUSH YDS/G
118.1
17th
PASS YDS/G
240.3
8th
NFL 2025 Leaders
NFL 2025 Rankings
NFL Fantasy 2025
NFL 2025 Betting
NFL 2025 Standings
| AFC East | W | L | T | PCT |
|---|---|---|---|---|
 Patriots - y | 14 | 3 | 0 | .824 |
 Bills - w | 12 | 5 | 0 | .706 |
 Dolphins - e | 7 | 10 | 0 | .412 |
 Jets - e | 3 | 14 | 0 | .176 |
| AFC North | W | L | T | PCT |
 Steelers - y | 10 | 7 | 0 | .588 |
 Ravens - e | 8 | 9 | 0 | .471 |
 Bengals - e | 6 | 11 | 0 | .353 |
 Browns - e | 5 | 12 | 0 | .294 |
| AFC South | W | L | T | PCT |
 Jaguars - y | 13 | 4 | 0 | .765 |
 Texans - w | 12 | 5 | 0 | .706 |
 Colts - e | 8 | 9 | 0 | .471 |
 Titans - e | 3 | 14 | 0 | .176 |
| AFC West | W | L | T | PCT |
 Broncos - z* | 14 | 3 | 0 | .824 |
 Chargers - w | 11 | 6 | 0 | .647 |
 Chiefs - e | 6 | 11 | 0 | .353 |
 Raiders - e | 3 | 14 | 0 | .176 |
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
 Eagles - y | 11 | 6 | 0 | .647 |
 Cowboys - e | 7 | 9 | 1 | .441 |
 Commanders - e | 5 | 12 | 0 | .294 |
 Giants - e | 4 | 13 | 0 | .235 |
| NFC North | W | L | T | PCT |
 Bears - y | 11 | 6 | 0 | .647 |
 Packers - w | 9 | 7 | 1 | .559 |
 Vikings - e | 9 | 8 | 0 | .529 |
 Lions - e | 9 | 8 | 0 | .529 |
| NFC South | W | L | T | PCT |
 Panthers - y | 8 | 9 | 0 | .471 |
 Buccaneers - e | 8 | 9 | 0 | .471 |
 Falcons - e | 8 | 9 | 0 | .471 |
 Saints - e | 6 | 11 | 0 | .353 |
| NFC West | W | L | T | PCT |
 Seahawks - z* | 14 | 3 | 0 | .824 |
 Rams - w | 12 | 5 | 0 | .706 |
 49ers - w | 12 | 5 | 0 | .706 |
 Cardinals - e | 3 | 14 | 0 | .176 |