Aaron Donald had the most sacks in a game in 2018, with 4 sacks versus the 49ers on October 21, 2018.

defense with the most sacks in a single game in 2018
Interpreted as:
defense with the most defensive sacks by a player in a single regular-season game in 2018
10/21/2018Donald11/4/2018Hunter12/30/2018Cox12/23/2018Donald12/16/2018Atkins12/15/2018Anderson12/2/2018Autry12/2/2018Hill11/29/2018Onyemata11/25/2018Judon11/15/2018Fackrell11/4/2018Addison10/28/2018Ford10/14/2018Smith10/14/2018Chubb10/7/2018Watt9/30/2018Lawrence9/30/2018Fackrell9/23/2018Watt9/9/2018Watt9/9/2018Miller12/30/2018Vernon12/16/2018Mack4.03.53.03.03.03.03.03.03.03.03.03.03.03.03.03.03.03.03.03.03.02.52.5
NAMEDATETMOPPSCKTKLASTCOMBSCKYINTINT YDSINT TDFFFRFR TD
Aaron DonaldAaron Donald10/21/2018LARLAR@ SF
@
4.081929000110
Danielle HunterDanielle Hunter11/4/2018MINMINvs. DET
vs.
3.563914.5000011
Fletcher CoxFletcher Cox12/30/2018PHIPHI@ WAS
@
3.040420000100
Aaron DonaldAaron Donald12/23/2018LARLAR@ ARI
@
3.052721000000
Geno AtkinsGeno Atkins12/16/2018CINCINvs. OAK
vs.
3.051620000000
Henry AndersonHenry Anderson12/15/2018NYJNYJvs. HOU
vs.
3.031426000000
Denico AutryDenico Autry12/2/2018INDIND@ JAX
@
3.061718000200
B.J. HillB.J. Hill12/2/2018NYGNYGvs. CHI
vs.
3.030316000000
David OnyemataDavid Onyemata11/29/2018NONO@ DAL
@
3.043721000100
Matt JudonMatt Judon11/25/2018BALBALvs. OAK
vs.
3.032512000100
Kyler FackrellKyler Fackrell11/15/2018GBGB@ SEA
@
3.051620000000
Mario AddisonMario Addison11/4/2018CARCARvs. TB
vs.
3.032524000100
Dee FordDee Ford10/28/2018KCKCvs. DEN
vs.
3.041519000200
Za'Darius SmithZa'Darius Smith10/14/2018BALBAL@ TEN
@
3.041518000100
Bradley ChubbBradley Chubb10/14/2018DENDENvs. LAR
vs.
3.041516000000
T.J. WattT.J. Watt10/7/2018PITPITvs. ATL
vs.
3.062825000100
Demarcus LawrenceDemarcus Lawrence9/30/2018DALDALvs. DET
vs.
3.062821000000
Kyler FackrellKyler Fackrell9/30/2018GBGBvs. BUF
vs.
3.040424000000
J.J. WattJ.J. Watt9/23/2018HOUHOUvs. NYG
vs.
3.044825000100
T.J. WattT.J. Watt9/9/2018PITPIT@ CLE
@
3.0731016000000
Von MillerVon Miller9/9/2018DENDENvs. SEA
vs.
3.061719000210
Olivier VernonOlivier Vernon12/30/2018NYGNYGvs. DAL
vs.
2.53259.5000000
Khalil MackKhalil Mack12/16/2018CHICHIvs. GB
vs.
2.551615000000
Chris JonesChris Jones12/13/2018KCKCvs. LAC
vs.
2.521315.5000000
Christian CovingtonChristian Covington11/26/2018HOUHOUvs. TEN
vs.
2.531416000000
StatMuse has game-level data for sacks going back to the 1982 season.

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