Jacoby Brissett had his most passing yards in a game versus the 49ers on November 16, with 452 yards.
Interpreted as:
Jacoby Brissett most passing yards in a regular-season game| NAME | YDS | DATE | TM | OPP | CMP | ATT | PCT | AVG | TD | INT | RTG | TD% | INT% | SCK | SCKY | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | J. Brissett | 452 | 11/16/2025 |  ARI | vs |  SF | 47 | 57 | 82.5 | 7.9 | 2 | 2 | 96.8 | 3.5 | 3.5 | 0 | 0 |
| 2 |  | J. Brissett | 326 | 10/20/2019 |  IND | vs |  HOU | 26 | 39 | 66.7 | 8.4 | 4 | 0 | 126.7 | 10.3 | 0.0 | 1 | 5 |
| 3 |  | J. Brissett | 324 | 11/20/2022 |  CLE | @ |  BUF | 28 | 41 | 68.3 | 7.9 | 3 | 0 | 116.3 | 7.3 | 0.0 | 1 | 8 |
| 4 | | J. Brissett | 320 | 10/12/2025 | ARI | @ | IND | 27 | 44 | 61.4 | 7.3 | 2 | 1 | 89.2 | 4.5 | 2.3 | 2 | 8 |
| 5 | | J. Brissett | 319 | 12/1/2019 | IND | vs |  TEN | 25 | 40 | 62.5 | 8.0 | 1 | 2 | 74.9 | 2.5 | 5.0 | 3 | 10 |
| 6 | | J. Brissett | 317 | 11/23/2025 | ARI | vs |  JAX | 33 | 49 | 67.3 | 6.5 | 1 | 0 | 92.0 | 2.0 | 0.0 | 6 | 44 |
| 7 | | J. Brissett | 314 | 10/8/2017 | IND | vs | SF | 22 | 34 | 64.7 | 9.2 | 0 | 1 | 82.2 | 0.0 | 2.9 | 4 | 26 |
| 8 | | J. Brissett | 310 | 9/22/2019 | IND | vs |  ATL | 28 | 37 | 75.7 | 8.4 | 2 | 0 | 118.1 | 5.4 | 0.0 | 1 | 10 |
| 9 | | J. Brissett | 308 | 11/5/2017 | IND | @ | HOU | 20 | 30 | 66.7 | 10.3 | 2 | 0 | 122.6 | 6.7 | 0.0 | 3 | 29 |
| 10 | | J. Brissett | 301 | 11/30/2025 | ARI | @ |  TB | 29 | 40 | 72.5 | 7.5 | 2 | 1 | 100.1 | 5.0 | 2.5 | 2 | 10 |
| 11 | | J. Brissett | 279 | 10/19/2025 | ARI | vs |  GB | 25 | 36 | 69.4 | 7.8 | 2 | 0 | 110.8 | 5.6 | 0.0 | 6 | 43 |
| 12 | | J. Brissett | 278 | 10/31/2022 | CLE | vs |  CIN | 17 | 22 | 77.3 | 12.6 | 1 | 0 | 133.7 | 4.5 | 0.0 | 2 | 10 |
| 13 |  | J. Brissett | 275 | 10/10/2021 |  MIA | @ | TB | 27 | 39 | 69.2 | 7.1 | 2 | 1 | 95.6 | 5.1 | 2.6 | 3 | 13 |
| 14 | | J. Brissett | 271 | 12/7/2025 | ARI | vs |  LAR | 25 | 44 | 56.8 | 6.2 | 2 | 1 | 80.8 | 4.5 | 2.3 | 3 | 8 |
| 15 | | J. Brissett | 266 | 10/16/2022 | CLE | vs |  NE | 21 | 45 | 46.7 | 5.9 | 1 | 2 | 54.5 | 2.2 | 4.4 | 4 | 8 |
| 16 | | J. Brissett | 265 | 9/29/2019 | IND | vs |  OAK | 24 | 46 | 52.2 | 5.8 | 3 | 1 | 82.2 | 6.5 | 2.2 | 0 | 0 |
| 17 | | J. Brissett | 261 | 11/3/2025 | ARI | @ |  DAL | 21 | 31 | 67.7 | 8.4 | 2 | 0 | 115.1 | 6.5 | 0.0 | 5 | 40 |
| 18 | | J. Brissett | 259 | 9/24/2017 | IND | vs | CLE | 17 | 24 | 70.8 | 10.8 | 1 | 0 | 120.0 | 4.2 | 0.0 | 3 | 16 |
| 19 | | J. Brissett | 258 | 11/9/2025 | ARI | @ |  SEA | 22 | 44 | 50.0 | 5.9 | 2 | 0 | 83.3 | 4.5 | 0.0 | 5 | 52 |
| 20 | | J. Brissett | 258 | 10/23/2022 | CLE | @ |  BAL | 22 | 27 | 81.5 | 9.6 | 0 | 0 | 106.5 | 0.0 | 0.0 | 5 | 35 |
| 21 | | J. Brissett | 251 | 12/8/2019 | IND | @ | TB | 19 | 36 | 52.8 | 7.0 | 2 | 0 | 93.6 | 5.6 | 0.0 | 1 | 8 |
| 22 | | J. Brissett | 244 | 11/7/2021 | MIA | vs | HOU | 26 | 43 | 60.5 | 5.7 | 1 | 2 | 64.5 | 2.3 | 4.7 | 4 | 29 |
| 23 | | J. Brissett | 234 | 10/2/2022 | CLE | @ | ATL | 21 | 35 | 60.0 | 6.7 | 0 | 1 | 68.0 | 0.0 | 2.9 | 1 | 8 |
| 24 | | J. Brissett | 233 | 10/29/2017 | IND | @ | CIN | 25 | 39 | 64.1 | 6.0 | 2 | 1 | 86.8 | 5.1 | 2.6 | 4 | 17 |
| 25 | | J. Brissett | 230 | 10/9/2022 | CLE | vs |  LAC | 21 | 34 | 61.8 | 6.8 | 1 | 1 | 79.3 | 2.9 | 2.9 | 0 | 0 |
Results may be incomplete. StatMuse has complete game-level data for passing yards going back to the 1950 season.
More Cardinals Stats
Team Rankings
PPG
21.7
21st
OPP PPG
26.8
26th
RUSH YDS/G
96.8
26th
PASS YDS/G
263.0
3rd
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