The Jacksonville Jaguars have a 10-11 record in the regular-season and playoffs against the Bills all-time.
| TEAM | DATE | REC | TM | OPP | RESULT | W% | TD | 1DWN | OFF | OPP OFF | 3DWN% | 4DWN% | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | Jaguars | 12/28/1996 | 1-0 | @ | W 30-27 | 1.000 | 3 | 18 | 409 | 308 | 41.2 | 100.0 | ||
| 2 | | Jaguars | 12/14/1997 | 1-0 | @ | W 20-14 | 1.000 | 2 | 20 | 388 | 335 | 30.8 | 0.0 | ||
| 3 | | Jaguars | 10/18/1998 | 0-1 | @ | L 16-17 | .000 | 1 | 16 | 238 | 337 | 43.8 | 100.0 | ||
| 4 | | Jaguars | 10/18/2001 | 0-1 | vs | L 10-13 | .000 | 1 | 14 | 247 | 317 | 30.0 | 0.0 | ||
| 5 | | Jaguars | 9/14/2003 | 0-1 | vs | L 17-38 | .000 | 2 | 20 | 287 | 371 | 28.6 | 75.0 | ||
| 6 | | Jaguars | 9/12/2004 | 1-0 | @ | W 13-10 | 1.000 | 1 | 14 | 225 | 242 | 15.4 | 100.0 | ||
| 7 | | Jaguars | 11/26/2006 | 0-1 | @ | L 24-27 | .000 | 3 | 19 | 323 | 241 | 9.1 | 100.0 | ||
| 8 | | Jaguars | 11/25/2007 | 1-0 | vs | W 36-14 | 1.000 | 3 | 21 | 416 | 297 | 56.3 | 0.0 | ||
| 9 | | Jaguars | 9/14/2008 | 0-1 | vs | L 16-20 | .000 | 1 | 19 | 243 | 285 | 18.2 | 100.0 | ||
| 10 | | Jaguars | 11/22/2009 | 1-0 | vs | W 18-15 | 1.000 | 2 | 19 | 310 | 343 | 60.0 | |||
| 11 | | Jaguars | 10/10/2010 | 1-0 | @ | W 36-26 | 1.000 | 3 | 21 | 381 | 306 | 36.4 | 0.0 | ||
| 12 | | Jaguars | 12/2/2012 | 0-1 | @ | L 18-34 | .000 | 2 | 21 | 236 | 344 | 10.0 | 0.0 | ||
| 13 | | Jaguars | 12/15/2013 | 0-1 | vs | L 20-27 | .000 | 2 | 22 | 354 | 366 | 53.3 | 0.0 | ||
| 14 | | Jaguars | 10/25/2015 | 1-0 | vs | W 34-31 | 1.000 | 5 | 17 | 295 | 375 | 35.7 | 0.0 | ||
| 15 | | Jaguars | 11/27/2016 | 0-1 | @ | L 21-28 | .000 | 3 | 20 | 301 | 304 | 53.3 | 0.0 | ||
| 16 | | Jaguars | 1/7/2018 | 1-0 | vs | W 10-3 | 1.000 | 1 | 15 | 230 | 263 | 16.7 | 100.0 | ||
| 17 | | Jaguars | 11/25/2018 | 0-1 | @ | L 21-24 | .000 | 3 | 25 | 333 | 327 | 38.5 | |||
| 18 | | Jaguars | 11/7/2021 | 1-0 | vs | W 9-6 | 1.000 | 0 | 16 | 218 | 301 | 15.4 | 100.0 | ||
| 19 | | Jaguars | 10/8/2023 | 1-0 | @ | W 25-20 | 1.000 | 3 | 29 | 474 | 388 | 55.6 | |||
| 20 | | Jaguars | 9/23/2024 | 0-1 | @ | L 10-47 | .000 | 1 | 19 | 239 | 388 | 15.4 | 50.0 | ||
| 21 | | Jaguars | 1/11/2026 | 0-1 | vs | L 24-27 | .000 | 3 | 20 | 359 | 340 | 55.6 | 0.0 | ||
| Average | .476 | 2.1 | 19.3 | 309.8 | 322.8 | 35.8 | 3.0 | ||||||||
| Total | 10-11 | .476 | 45 | 405 | 6,506 | 6,778 | 35.8 | 54.3 |
More Jaguars Stats
Team Leaders 
PASS
207
Lawrence
RUSH
67
Etienne
REC
107
Washington
Team Rankings
PPG
27.9
6th
OPP PPG
19.8
8th
RUSH YDS/G
115.1
20th
PASS YDS/G
236.8
11th
NFL 2025 Leaders
NFL 2025 Rankings
NFL Fantasy 2025
NFL 2025 Betting
NFL 2025 Standings
| AFC East | W | L | T | PCT |
|---|---|---|---|---|
 Patriots - y | 14 | 3 | 0 | .824 |
 Bills - w | 12 | 5 | 0 | .706 |
 Dolphins - e | 7 | 10 | 0 | .412 |
 Jets - e | 3 | 14 | 0 | .176 |
| AFC North | W | L | T | PCT |
 Steelers - y | 10 | 7 | 0 | .588 |
 Ravens - e | 8 | 9 | 0 | .471 |
 Bengals - e | 6 | 11 | 0 | .353 |
 Browns - e | 5 | 12 | 0 | .294 |
| AFC South | W | L | T | PCT |
 Jaguars - y | 13 | 4 | 0 | .765 |
 Texans - w | 12 | 5 | 0 | .706 |
 Colts - e | 8 | 9 | 0 | .471 |
 Titans - e | 3 | 14 | 0 | .176 |
| AFC West | W | L | T | PCT |
 Broncos - z* | 14 | 3 | 0 | .824 |
 Chargers - w | 11 | 6 | 0 | .647 |
 Chiefs - e | 6 | 11 | 0 | .353 |
 Raiders - e | 3 | 14 | 0 | .176 |
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
 Eagles - y | 11 | 6 | 0 | .647 |
 Cowboys - e | 7 | 9 | 1 | .441 |
 Commanders - e | 5 | 12 | 0 | .294 |
 Giants - e | 4 | 13 | 0 | .235 |
| NFC North | W | L | T | PCT |
 Bears - y | 11 | 6 | 0 | .647 |
 Packers - w | 9 | 7 | 1 | .559 |
 Vikings - e | 9 | 8 | 0 | .529 |
 Lions - e | 9 | 8 | 0 | .529 |
| NFC South | W | L | T | PCT |
 Panthers - y | 8 | 9 | 0 | .471 |
 Buccaneers - e | 8 | 9 | 0 | .471 |
 Falcons - e | 8 | 9 | 0 | .471 |
 Saints - e | 6 | 11 | 0 | .353 |
| NFC West | W | L | T | PCT |
 Seahawks - z* | 14 | 3 | 0 | .824 |
 Rams - w | 12 | 5 | 0 | .706 |
 49ers - w | 12 | 5 | 0 | .706 |
 Cardinals - e | 3 | 14 | 0 | .176 |
