Patrick Mahomes had his most passing yards in a game against the Rams on November 19, 2018, with 478 yards.
Interpreted as:
mahomes most passing yards in regular-season game| NAME | YDS | DATE | TM | OPP | CMP | ATT | PCT | AVG | TD | INT | RTG | TD% | INT% | SCK | SCKY | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | P. Mahomes | 478 | 11/19/2018 |  KC | @ |  LAR | 33 | 46 | 71.7 | 10.4 | 6 | 3 | 117.6 | 13.0 | 6.5 | 3 | 30 |
| 2 | | P. Mahomes | 462 | 11/29/2020 | KC | @ |  TB | 37 | 49 | 75.5 | 9.4 | 3 | 0 | 124.7 | 6.1 | 0.0 | 2 | 6 |
| 3 | | P. Mahomes | 446 | 11/6/2022 | KC | vs |  TEN | 43 | 68 | 63.2 | 6.6 | 1 | 1 | 80.9 | 1.5 | 1.5 | 4 | 24 |
| 4 | | P. Mahomes | 446 | 11/10/2019 | KC | @ | TEN | 36 | 50 | 72.0 | 8.9 | 3 | 0 | 119.3 | 6.0 | 0.0 | 2 | 13 |
| 5 | | P. Mahomes | 443 | 9/15/2019 | KC | @ |  OAK | 30 | 44 | 68.2 | 10.1 | 4 | 0 | 131.2 | 9.1 | 0.0 | 2 | 7 |
| 6 | | P. Mahomes | 424 | 10/22/2023 | KC | vs |  LAC | 32 | 42 | 76.2 | 10.1 | 4 | 1 | 129.5 | 9.5 | 2.4 | 1 | 9 |
| 7 | | P. Mahomes | 423 | 10/23/2022 | KC | @ |  SF | 25 | 34 | 73.5 | 12.4 | 3 | 1 | 132.4 | 8.8 | 2.9 | 1 | 6 |
| 8 | | P. Mahomes | 416 | 11/1/2020 | KC | vs |  NYJ | 31 | 42 | 73.8 | 9.9 | 5 | 0 | 144.4 | 11.9 | 0.0 | 0 | 0 |
| 9 | | P. Mahomes | 410 | 12/16/2021 | KC | @ | LAC | 31 | 47 | 66.0 | 8.7 | 3 | 1 | 105.8 | 6.4 | 2.1 | 1 | 0 |
| 10 | | P. Mahomes | 406 | 11/14/2021 | KC | @ | LV | 35 | 50 | 70.0 | 8.1 | 5 | 0 | 127.6 | 10.0 | 0.0 | 0 | 0 |
| 11 | | P. Mahomes | 397 | 10/17/2021 | KC | @ |  WAS | 32 | 47 | 68.1 | 8.4 | 2 | 2 | 90.5 | 4.3 | 4.3 | 3 | 7 |
| 12 | | P. Mahomes | 393 | 12/13/2020 | KC | @ |  MIA | 24 | 34 | 70.6 | 11.6 | 2 | 3 | 91.9 | 5.9 | 8.8 | 3 | 39 |
| 13 | | P. Mahomes | 385 | 9/28/2020 | KC | @ |  BAL | 31 | 42 | 73.8 | 9.2 | 4 | 0 | 133.5 | 9.5 | 0.0 | 0 | 0 |
| 14 | | P. Mahomes | 378 | 9/8/2019 | KC | @ |  JAX | 25 | 33 | 75.8 | 11.5 | 3 | 0 | 143.2 | 9.1 | 0.0 | 0 | 0 |
| 15 | | P. Mahomes | 377 | 12/9/2018 | KC | vs | BAL | 35 | 53 | 66.0 | 7.1 | 2 | 1 | 91.5 | 3.8 | 1.9 | 3 | 29 |
| 16 | | P. Mahomes | 375 | 11/4/2018 | KC | @ |  CLE | 23 | 32 | 71.9 | 11.7 | 3 | 1 | 129.0 | 9.4 | 3.1 | 2 | 15 |
| 17 | | P. Mahomes | 374 | 9/22/2019 | KC | vs | BAL | 27 | 37 | 73.0 | 10.1 | 3 | 0 | 132.0 | 8.1 | 0.0 | 1 | 11 |
| 18 | | P. Mahomes | 372 | 11/8/2020 | KC | vs |  CAR | 30 | 45 | 66.7 | 8.3 | 4 | 0 | 121.7 | 8.9 | 0.0 | 2 | 11 |
| 19 | | P. Mahomes | 360 | 9/11/2022 | KC | @ |  ARI | 30 | 39 | 76.9 | 9.2 | 5 | 0 | 144.2 | 12.8 | 0.0 | 0 | 0 |
| 20 | | P. Mahomes | 358 | 10/21/2018 | KC | vs |  CIN | 28 | 39 | 71.8 | 9.2 | 4 | 1 | 123.7 | 10.3 | 2.6 | 2 | 5 |
| 21 | | P. Mahomes | 352 | 12/11/2022 | KC | @ |  DEN | 28 | 42 | 66.7 | 8.4 | 3 | 3 | 86.6 | 7.1 | 7.1 | 2 | 10 |
| 22 | | P. Mahomes | 352 | 10/14/2018 | KC | @ |  NE | 23 | 36 | 63.9 | 9.8 | 4 | 2 | 110.0 | 11.1 | 5.6 | 0 | 0 |
| 23 | | P. Mahomes | 348 | 11/22/2020 | KC | @ | LV | 34 | 45 | 75.6 | 7.7 | 2 | 1 | 102.8 | 4.4 | 2.2 | 0 | 0 |
| 24 | | P. Mahomes | 343 | 9/19/2021 | KC | @ | BAL | 24 | 31 | 77.4 | 11.1 | 3 | 1 | 131.5 | 9.7 | 3.2 | 0 | 0 |
| 25 | | P. Mahomes | 340 | 10/11/2020 | KC | vs | LV | 22 | 43 | 51.2 | 7.9 | 2 | 1 | 83.5 | 4.7 | 2.3 | 3 | 7 |
Results may be incomplete. StatMuse has complete game-level data for passing yards going back to the 1950 season.
More Chiefs Stats
Team Rankings
PPG
24.3
14th
OPP PPG
19.0
7th
RUSH YDS/G
110.5
19th
PASS YDS/G
234.8
12th
BUF 
NFL 2025 Leaders
NFL 2025 Rankings
NFL Fantasy 2025
NFL 2025 Betting
NFL 2025 Division Standings
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
 Eagles | 4 | 0 | 0 | 1.000 |
 Commanders | 2 | 2 | 0 | .500 |
| NFC North | W | L | T | PCT |
 Lions | 3 | 1 | 0 | .750 |
 Packers | 2 | 1 | 1 | .625 |
| NFC South | W | L | T | PCT |
| Buccaneers | 3 | 1 | 0 | .750 |
 Falcons | 2 | 2 | 0 | .500 |
| NFC West | W | L | T | PCT |
| 49ers | 4 | 1 | 0 | .800 |
 Seahawks | 3 | 1 | 0 | .750 |
Steelers 
Colts 
DAL 
NYJ 
MIN 
HOU 
NYG 
NO 
