Matthew Stafford has a passer rating of 86.0 with 2,781 yards, 15 touchdowns and 8 interceptions in 11 games against the 49ers in his career.
| NAME | DATE | TM | OPP | CMP | ATT | PCT | YDS | AVG | TD | INT | RTG | TD% | INT% | SCK | SCKY | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | M. Stafford | 10/16/2011 |  DET | vs |  SF | 28 | 50 | 56.0 | 293 | 5.9 | 2 | 0 | 86.5 | 4.0 | 0.0 | 5 | 49 |
| 2 | | M. Stafford | 9/16/2012 | DET | @ | SF | 19 | 32 | 59.4 | 230 | 7.2 | 1 | 1 | 78.9 | 3.1 | 3.1 | 2 | 16 |
| 3 | | M. Stafford | 12/27/2015 | DET | vs | SF | 29 | 37 | 78.4 | 301 | 8.1 | 2 | 0 | 118.6 | 5.4 | 0.0 | 2 | 17 |
| 4 | | M. Stafford | 9/16/2018 | DET | @ | SF | 34 | 53 | 64.2 | 347 | 6.5 | 3 | 0 | 101.7 | 5.7 | 0.0 | 2 | 18 |
| 5 |  | M. Stafford | 11/15/2021 |  LAR | @ | SF | 26 | 41 | 63.4 | 243 | 5.9 | 1 | 2 | 67.4 | 2.4 | 4.9 | 2 | 19 |
| 6 | | M. Stafford | 1/9/2022 | LAR | vs | SF | 21 | 32 | 65.6 | 238 | 7.4 | 3 | 2 | 93.0 | 9.4 | 6.3 | 5 | 37 |
| 7 | | M. Stafford | 10/3/2022 | LAR | @ | SF | 32 | 48 | 66.7 | 254 | 5.3 | 0 | 1 | 71.0 | 0.0 | 2.1 | 7 | 54 |
| 8 | | M. Stafford | 10/30/2022 | LAR | vs | SF | 22 | 33 | 66.7 | 187 | 5.7 | 1 | 0 | 91.4 | 3.0 | 0.0 | 2 | 20 |
| 9 | | M. Stafford | 9/17/2023 | LAR | vs | SF | 34 | 55 | 61.8 | 307 | 5.6 | 1 | 2 | 67.8 | 1.8 | 3.6 | 1 | 10 |
| 10 | | M. Stafford | 9/22/2024 | LAR | vs | SF | 16 | 25 | 64.0 | 221 | 8.8 | 1 | 0 | 105.6 | 4.0 | 0.0 | 3 | 23 |
| 11 | | M. Stafford | 12/12/2024 | LAR | @ | SF | 16 | 27 | 59.3 | 160 | 5.9 | 0 | 0 | 76.2 | 0.0 | 0.0 | 0 | 0 |
| Average | 25.2 | 39.4 | 64.0 | 252.8 | 6.4 | 1.4 | 0.7 | 86.0 | 3.5 | 1.8 | 2.8 | 23.9 | ||||||
| Total | 277 | 433 | 64.0 | 2,781 | 6.4 | 15 | 8 | 86.0 | 3.5 | 1.8 | 31 | 263 |
More Rams Stats
Team Rankings
PPG
25.0
13th
OPP PPG
20.3
10th
RUSH YDS/G
120.8
13th
PASS YDS/G
278.5
3rd
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NO 
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NFL 2025 Division Standings
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
 Eagles | 4 | 0 | 0 | 1.000 |
 Commanders | 2 | 2 | 0 | .500 |
| NFC North | W | L | T | PCT |
| Lions | 3 | 1 | 0 | .750 |
 Packers | 2 | 1 | 1 | .625 |
| NFC South | W | L | T | PCT |
 Buccaneers | 3 | 1 | 0 | .750 |
 Falcons | 2 | 2 | 0 | .500 |
| NFC West | W | L | T | PCT |
| 49ers | 3 | 1 | 0 | .750 |
 Seahawks | 3 | 1 | 0 | .750 |
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