Morten Andersen had the most games with exactly 0 interceptions, with 382 games.

most games with no interceptions
Interpreted as:
most regular-season games with no defensive interceptions by a player
AndersenVinatieriAndersonFeaglesHansonDawsonRiceFavreCarneyBradyKasayStoverMatthewsBreesLechlerJanikowskiLandetaJunkinMarshallSmithJohnsonWitten382365353352327305303302302301301297296287286284284281281277273271
NAMEGPINTTKLASTCOMBSCKSCKYINT YDSINT TDFFFRFR TD
Morten AndersenMorten Andersen38201120.00000
Adam VinatieriAdam Vinatieri3650114150.00000
Gary AndersonGary Anderson35300000.00000
Jeff FeaglesJeff Feagles35208190.00000
Jason HansonJason Hanson3270175220.00000
Phil DawsonPhil Dawson3050123150.00000
Jerry RiceJerry Rice30307070.00001
Brett FavreBrett Favre30206170.00000
John CarneyJohn Carney30201010.00000
Tom BradyTom Brady3010130130.00000
John KasayJohn Kasay30102020.00000
Matt StoverMatt Stover29708080.00000
Bruce MatthewsBruce Matthews29600000.00000
Drew BreesDrew Brees2870160160.00000340
Shane LechlerShane Lechler2860192210.00000
Sebastian JanikowskiSebastian Janikowski2840180180.00000
Sean LandetaSean Landeta28400000.00000
Trey JunkinTrey Junkin28102020.00000
Jim MarshallJim Marshall2810001
Bruce SmithBruce Smith27708528113198.50061
Norm JohnsonNorm Johnson27300.0000
Jason WittenJason Witten2710390390.0000020
Tony GonzalezTony Gonzalez2700250250.00000
Peyton ManningPeyton Manning26609090.00000
Andy LeeAndy Lee264092110.0000010
StatMuse has game-level data for interceptions going back to the 1960 season.

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