most losses by a qb while throwing for 300 yards in a career

Drew Brees has lost the most career games by a quarterback when throwing for 300+ yards, with 42 losses.

Interpreted as:
most regular-season losses by a qb while throwing for 300 or more yards in a career
NAMELYDSGPCMPATTPCTAVGYDS/GTDINTRTGTD%INT%SCKSCKY
1Drew Brees
D. Brees
42
43,967
123
3,585
5,129
69.9
8.6
357.5
328
108
108.6
6.4
2.1
174
1,201
2Matt Ryan
M. Ryan
37
26,296
76
2,216
3,201
69.2
8.2
346.0
154
54
103.0
4.8
1.7
159
1,083
3Philip Rivers
P. Rivers
34
25,525
73
1,969
2,908
67.7
8.8
349.7
162
76
102.8
5.6
2.6
132
770
4Eli Manning
E. Manning
32
18,135
51
1,415
2,192
64.6
8.3
355.6
114
68
94.8
5.2
3.1
80
528
5Peyton Manning
P. Manning
32
32,408
93
2,563
3,802
67.4
8.5
348.5
238
98
103.9
6.3
2.6
116
790
6Carson Palmer
C. Palmer
29
18,037
52
1,402
2,184
64.2
8.3
346.9
111
55
96.4
5.1
2.5
122
869
7Ben Roethlisberger
B. Roethlisberger
28
24,563
68
1,948
2,894
67.3
8.5
361.2
159
72
101.5
5.5
2.5
153
999
8Matthew Stafford
M. Stafford
26
24,188
68
1,869
2,866
65.2
8.4
355.7
159
54
102.2
5.5
1.9
126
890
9Dan Marino
D. Marino
26
22,430
63
1,653
2,673
61.8
8.4
356.0
167
85
96.2
6.2
3.2
76
609
10Kirk Cousins
K. Cousins
25
19,061
54
1,555
2,200
70.7
8.7
353.0
130
37
109.8
5.9
1.7
110
830
11Dan Fouts
D. Fouts
25
17,846
51
1,254
2,020
62.1
8.8
349.9
108
79
92.2
5.3
3.9
12Warren Moon
W. Moon
23
17,291
49
1,283
2,077
61.8
8.3
352.9
100
70
90.3
4.8
3.4
105
758
13Aaron Rodgers
A. Rodgers
22
24,177
70
1,859
2,757
67.4
8.8
345.4
197
28
114.4
7.1
1.0
172
1,162
14Tom Brady
T. Brady
22
40,096
113
3,228
4,728
68.3
8.5
354.8
302
68
109.6
6.4
1.4
191
1,177
15Vinny Testaverde
V. Testaverde
22
10,502
30
785
1,324
59.3
7.9
350.1
61
52
83.5
4.6
3.9
59
462
16Brett Favre
B. Favre
21
21,089
62
1,648
2,536
65.0
8.3
340.1
149
63
100.1
5.9
2.5
99
701
17Jameis Winston
J. Winston
20
11,576
32
874
1,390
62.9
8.3
361.8
69
48
91.3
5.0
3.5
74
457
18Kurt Warner
K. Warner
19
17,958
52
1,381
2,038
67.8
8.8
345.3
113
62
101.1
5.5
3.0
120
799
19Joe Flacco
J. Flacco
18
14,611
43
1,196
1,881
63.6
7.8
339.8
93
40
95.1
4.9
2.1
84
576
20Trent Green
T. Green
18
10,500
30
759
1,165
65.2
9.0
350.0
66
25
103.9
5.7
2.1
69
389
21Kerry Collins
K. Collins
18
10,280
31
777
1,312
59.2
7.8
331.6
62
38
87.8
4.7
2.9
60
408
22Jared Goff
J. Goff
17
16,832
48
1,324
1,932
68.5
8.7
350.7
115
24
110.2
6.0
1.2
69
487
23Carson Wentz
C. Wentz
17
8,526
26
726
1,099
66.1
7.8
327.9
52
25
95.8
4.7
2.3
66
437
24Tony Romo
T. Romo
17
15,583
46
1,185
1,773
66.8
8.8
338.8
112
48
104.2
6.3
2.7
86
599
25Andrew Luck
A. Luck
16
11,633
33
927
1,497
61.9
7.8
352.5
87
39
94.6
5.8
2.6
66
418
StatMuse has game-level data for passing yards going back to the 1950 season.

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Team Leaders

PASS

2,384

Shough

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RUSH

471

Kamara

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REC

1,163

Olave

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Team Rankings

PPG

18.0

28th

OPP PPG

22.5

16th

RUSH YDS/G

94.3

28th

PASS YDS/G

236.9

10th

2025 Division Standings
TEAMWLTPCT
8
9
0
.471
8
9
0
.471
8
9
0
.471
Saints Saints
6
11
0
.353
Schedule
DATEMATCHUPTIME (ET)
Sun
9/13
@
1:00 PM
Sun
9/20
@
1:00 PM
Sun
9/27
@
4:25 PM
Mon
10/5
@
8:15 PM
Sun
10/11
@
1:00 PM
Last Game
NO Saints

6 - 11

17

Final

19

ATL Falcons

8 - 9

Sun 4 Jan 2026

NFL 2025 Leaders

NFL 2025 Rankings

NFL Fantasy 2025

NFL 2025 Betting

NFL 2025 Standings

AFC EastWLTPCT
14
3
0
.824
Bills Bills - w
12
5
0
.706
7
10
0
.412
Jets Jets - e
3
14
0
.176
AFC NorthWLTPCT
10
7
0
.588
8
9
0
.471
6
11
0
.353
5
12
0
.294
AFC SouthWLTPCT
13
4
0
.765
12
5
0
.706
Colts Colts - e
8
9
0
.471
3
14
0
.176
AFC WestWLTPCT
14
3
0
.824
11
6
0
.647
6
11
0
.353
3
14
0
.176
NFC EastWLTPCT
11
6
0
.647
7
9
1
.441
5
12
0
.294
4
13
0
.235
NFC NorthWLTPCT
Bears Bears - y
11
6
0
.647
9
7
1
.559
9
8
0
.529
Lions Lions - e
9
8
0
.529
NFC SouthWLTPCT
8
9
0
.471
8
9
0
.471
8
9
0
.471
6
11
0
.353
NFC WestWLTPCT
14
3
0
.824
Rams Rams - w
12
5
0
.706
49ers 49ers - w
12
5
0
.706
3
14
0
.176

NFL 2025 Scores & Schedule

Scores

DATEMATCHUPSCORE
Sun
10/12
@
29-27
Sun
10/12
@
27-30
Sun
10/12
@
25-19
Sun
10/12
@
10-20
Sun
10/12
@
18-27

Schedule

DATEMATCHUPTIME (ET)
Wed
9/9
@
8:20 PM
Thu
9/10
@
8:35 PM
Sun
9/13
@
1:00 PM
Sun
9/13
@
1:00 PM
Sun
9/13
@
1:00 PM