Matthew Stafford has the most passing yards for the Lions in a Week-2 game, with 347 yards versus the 49ers on September 16, 2018.

	NAME	YDS	DATE	TM		OPP	CMP	ATT	PCT	AVG	TD	INT	RTG	TD%	INT%	SCK	SCKY
1	Matthew Stafford M. Stafford	347	9/16/2018	DET	@	SF	34	53	64.2	6.5	3	0	101.7	5.7	0.0	2	18
2	Bob Gagliano B. Gagliano	344	9/17/1989	DET	@	NYG	21	31	67.7	11.1	1	3	75.9	3.2	9.7	4	29
3	Shaun Hill S. Hill	335	9/19/2010	DET	vs	PHI	25	45	55.6	7.4	2	2	75.7	4.4	4.4	2	6
4	Jared Goff J. Goff	334	9/14/2025	DET	vs	CHI	23	28	82.1	11.9	5	0	156.0	17.9	0.0	0	0
5	Scott Mitchell S. Mitchell	331	9/7/1997	DET	vs	TB	29	50	58.0	6.6	2	1	83.0	4.0	2.0	2	9
6	Jared Goff J. Goff	323	9/17/2023	DET	vs	SEA	28	35	80.0	9.2	3	1	121.8	8.6	2.9	2	7
7	Jared Goff J. Goff	307	9/15/2024	DET	vs	TB	34	55	61.8	5.6	0	2	61.7	0.0	3.6	0	0
8	Matthew Stafford M. Stafford	294	9/18/2011	DET	vs	KC	23	39	59.0	7.5	4	1	106.1	10.3	2.6	0	0
9	Matthew Stafford M. Stafford	291	9/14/2014	DET	@	CAR	27	48	56.3	6.1	1	1	72.5	2.1	2.1	4	38
10	Matthew Stafford M. Stafford	286	9/20/2015	DET	@	MIN	32	53	60.4	5.4	2	1	79.6	3.8	1.9	1	1
11	Scott Mitchell S. Mitchell	279	9/10/1995	DET	@	MIN	27	47	57.4	5.9	1	1	72.9	2.1	2.1	4	7
12	Bill Munson B. Munson	279	9/22/1968	DET	vs	CHI	15	23	65.2	12.1	3	1	128.4	13.0	4.3
13	Matthew Stafford M. Stafford	278	9/15/2013	DET	@	ARI	24	36	66.7	7.7	2	0	108.3	5.6	0.0	1	5
14	Jon Kitna J. Kitna	276	9/14/2008	DET	vs	GB	21	41	51.2	6.7	2	3	58.6	4.9	7.3	5	20
15	Milt Plum M. Plum	272	9/23/1962	DET	vs	SF	16	22	72.7	12.4	4	0	153.8	18.2	0.0
16	Rodney Peete R. Peete	271	9/8/1991	DET	vs	GB	25	38	65.8	7.1	1	0	95.4	2.6	0.0	0	0
17	Matthew Stafford M. Stafford	260	9/18/2016	DET	vs	TEN	22	40	55.0	6.5	1	1	72.9	2.5	2.5	4	22
18	Jared Goff J. Goff	256	9/18/2022	DET	vs	WAS	20	34	58.8	7.5	4	0	121.7	11.8	0.0	3	22
19	Chuck Long C. Long	255	9/20/1987	DET	@	RAI	21	35	60.0	7.3	1	2	68.2	2.9	5.7	2	11
20	Gary Danielson G. Danielson	250	9/9/1984	DET	@	ATL	21	32	65.6	7.8	2	0	110.2	6.3	0.0	1	9
21	Jared Goff J. Goff	246	9/20/2021	DET	@	GB	26	36	72.2	6.8	2	1	97.7	5.6	2.8	1	10
22	Gary Danielson G. Danielson	246	9/14/1980	DET	@	GB	11	17	64.7	14.5	1	0	127.7	5.9	0.0
23	Matthew Stafford M. Stafford	245	9/15/2019	DET	vs	LAC	22	30	73.3	8.2	2	2	91.7	6.7	6.7	0	0
24	Jon Kitna J. Kitna	245	9/16/2007	DET	vs	MIN	22	32	68.8	7.7	1	1	88.7	3.1	3.1	1	16
25	Matthew Stafford M. Stafford	244	9/20/2020	DET	@	GB	20	33	60.6	7.4	2	1	91.0	6.1	3.0	4	26

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Results may be incomplete. StatMuse has complete game-level data for passing yards going back to the 1950 season.

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TEAM	W	L	T	PCT
Bears	11	6	0	.647
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Smith-Njigba

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NFL 2025 Standings

AFC East	W	L	T	PCT
Patriots - y	14	3	0	.824
Bills - w	12	5	0	.706
Dolphins - e	7	10	0	.412
Jets - e	3	14	0	.176
AFC North	W	L	T	PCT
Steelers - y	10	7	0	.588
Ravens - e	8	9	0	.471
Bengals - e	6	11	0	.353
Browns - e	5	12	0	.294
AFC South	W	L	T	PCT
Jaguars - y	13	4	0	.765
Texans - w	12	5	0	.706
Colts - e	8	9	0	.471
Titans - e	3	14	0	.176
AFC West	W	L	T	PCT
Broncos - z*	14	3	0	.824
Chargers - w	11	6	0	.647
Chiefs - e	6	11	0	.353
Raiders - e	3	14	0	.176

NFC East	W	L	T	PCT
Eagles - y	11	6	0	.647
Cowboys - e	7	9	1	.441
Commanders - e	5	12	0	.294
Giants - e	4	13	0	.235
NFC North	W	L	T	PCT
Bears - y	11	6	0	.647
Packers - w	9	7	1	.559
Vikings - e	9	8	0	.529
Lions - e	9	8	0	.529
NFC South	W	L	T	PCT
Panthers - y	8	9	0	.471
Buccaneers - e	8	9	0	.471
Falcons - e	8	9	0	.471
Saints - e	6	11	0	.353
NFC West	W	L	T	PCT
Seahawks - z*	14	3	0	.824
Rams - w	12	5	0	.706
49ers - w	12	5	0	.706
Cardinals - e	3	14	0	.176