Dak Prescott has averaged the most passing yards per game with 4+ games played in a season, with 371.2 per game in 2020.

most passing yards per game in a season with at least 4 games played
Interpreted as:
most passing yards per game by a player in a season with at least 4 games played
2020Prescott2021Brady2013Manning2011Brees2015Roethlisberger2011Brady2016Brees2015Brees2012Brees2013Brees2021Carr2018Roethlisberger1982Fouts2019Winston2018Mahomes1984Marino2021Stafford2008Brees2020Mahomes2021Herbert2011Stafford1990Moon2019Stafford371.2353.4342.3342.3328.2327.2325.5324.7323.6322.6321.0320.6320.3319.3318.6317.8317.4316.8316.0315.2314.9312.6312.4
NAMESEASONTMGPYDS/GCMPATTPCTYDSAVGTDTD%INTINT%SCKSCKYRATE
Dak PrescottDak Prescott2020DALDAL5371.215122268.01,8568.494.141.8106699.6
Tom BradyTom Brady2021TBTB5353.414922566.21,7677.9156.720.9961108.5
Peyton ManningPeyton Manning2013DENDEN16342.345065968.35,4778.3558.3101.518120115.1
Drew BreesDrew Brees2011NONO16342.346865771.25,4768.3467.0142.124158110.6
Ben RoethlisbergerBen Roethlisberger2015PITPIT12328.231946968.03,9388.4214.5163.42014194.5
Tom BradyTom Brady2011NENE16327.240161165.65,2358.6396.4122.032173105.6
Drew BreesDrew Brees2016NONO16325.547167370.05,2087.7375.5152.227184101.7
Drew BreesDrew Brees2015NONO15324.742862768.34,8707.8325.1111.831235101.0
Drew BreesDrew Brees2012NONO16323.642267063.05,1777.7436.4192.82619096.3
Drew BreesDrew Brees2013NONO16322.644665068.65,1627.9396.0121.837244104.7
Derek CarrDerek Carr2021LVLV5321.013120563.91,6057.883.942.01511392.8
Ben RoethlisbergerBen Roethlisberger2018PITPIT16320.645267567.05,1297.6345.0162.42416696.5
Dan FoutsDan Fouts1982SDSD9320.320433061.82,8838.7175.2113.3129493.3
Jameis WinstonJameis Winston2019TBTB16319.338062660.75,1098.2335.3304.84728284.3
Patrick MahomesPatrick Mahomes2018KCKC16318.638358066.05,0978.8508.6122.126171113.8
Dan MarinoDan Marino1984MIAMIA16317.836256464.25,0849.0488.5173.013120108.9
Matthew StaffordMatthew Stafford2021LARLAR5317.411717268.01,5879.2127.031.7436113.2
Drew BreesDrew Brees2008NONO16316.841363565.05,0698.0345.4172.7139296.2
Patrick MahomesPatrick Mahomes2020KCKC15316.039058866.34,7408.1386.561.022147108.2
Justin HerbertJustin Herbert2021LACLAC5315.213920767.11,5767.6136.331.4961104.7
Matthew StaffordMatthew Stafford2011DETDET16314.942166363.55,0387.6416.2162.43625797.2
Warren MoonWarren Moon1990HOUHOU15312.636258462.04,6898.0335.7132.23625296.8
Matthew StaffordMatthew Stafford2019DETDET8312.418729164.32,4998.6196.551.718137106.0
Kurt WarnerKurt Warner2000STLSTL11311.723534767.73,4299.9216.1185.22011598.3
Matthew StaffordMatthew Stafford2012DETDET16310.443572759.84,9676.8202.8172.32921279.8
StatMuse has season-level data for passing yards per game going back to the 1932 season.

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