Cookie Gilchrist has earned the most PPR fantasy points by a Bills running back in a game, with 54.3 points against the Jets on December 8, 1963.
Interpreted as:
most ppr points scored by a bills running back player in a single regular-season game| NAME | FPTS (PPR) | DATE | TM | OPP | FPTS | FPTS (Half PPR) | RUSH YDS | ATT | YPC | RUSH TD | REC YDS | REC | TRG | AVG | REC TD | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | C. Gilchrist | 54.3 | 12/8/1963 | vs | 54.3 | 54.3 | 243 | 36 | 6.8 | 5 | 0 | 0 | 0 | ||||
| 2 | | J. Cribbs | 47.8 | 11/1/1981 | vs | 42.8 | 45.3 | 85 | 23 | 3.7 | 0 | 163 | 5 | 32.6 | 3 | |||
| 3 | | T. Thomas | 46.8 | 9/1/1991 | vs | 38.8 | 42.8 | 165 | 25 | 6.6 | 1 | 103 | 8 | 12.9 | 1 | |||
| 4 | | T. Henry | 41.8 | 9/8/2002 | vs | 35.8 | 38.8 | 149 | 31 | 4.8 | 3 | 29 | 6 | 8 | 4.8 | 0 | ||
| 5 |  | O.J. Simpson | 41.3 | 12/7/1975 | @ | 33.3 | 37.3 | 96 | 18 | 5.3 | 1 | 117 | 8 | 14.6 | 1 | |||
| 6 | | T. Thomas | 40.6 | 9/6/1992 | vs | 37.6 | 39.1 | 103 | 22 | 4.7 | 3 | 33 | 3 | 11.0 | 1 | |||
| 7 | | O.J. Simpson | 40.4 | 11/9/1975 | vs | 37.4 | 38.9 | 123 | 19 | 6.5 | 1 | 71 | 3 | 23.7 | 2 | |||
| 8 | | J. Braxton | 40.3 | 11/27/1975 | @ | 37.3 | 38.8 | 160 | 34 | 4.7 | 3 | 33 | 3 | 11.0 | 0 | |||
| 9 | | W. McGahee | 40.2 | 11/28/2004 | @ | 38.2 | 39.2 | 116 | 28 | 4.1 | 4 | 26 | 2 | 4 | 13.0 | 0 | ||
| 10 | | R. Hooks | 40 | 9/9/1979 | vs | 37 | 38.5 | 70 | 5 | 14.0 | 4 | 60 | 3 | 20.0 | 0 | |||
| 11 | | O.J. Simpson | 39.3 | 11/25/1976 | @ | 39.3 | 39.3 | 273 | 29 | 9.4 | 2 | 0 | 0 | 0 | ||||
| 12 | | C.J. Spiller | 37.7 | 12/18/2011 | vs | 28.7 | 33.2 | 91 | 12 | 7.6 | 1 | 76 | 9 | 11 | 8.4 | 1 | ||
| 13 | | W. Carlton | 37.2 | 10/23/1960 | vs | 32.2 | 34.7 | 32 | 11 | 2.9 | 0 | 110 | 5 | 22.0 | 3 | |||
| 14 | | A. Smith | 37.1 | 9/21/1997 | vs | 34.1 | 35.6 | 129 | 12 | 10.8 | 3 | 32 | 3 | 10.7 | 0 | |||
| 15 | | O.J. Simpson | 37.1 | 11/23/1975 | vs | 33.1 | 35.1 | 69 | 27 | 2.6 | 2 | 22 | 4 | 5.5 | 2 | |||
| 16 | | O.J. Simpson | 36.9 | 9/16/1973 | @ | 36.9 | 36.9 | 250 | 29 | 8.6 | 2 | 0 | 0 | 0 | ||||
| 17 | | T. Thomas | 36.4 | 9/15/1991 | @ | 23.4 | 29.9 | 62 | 11 | 5.6 | 0 | 112 | 13 | 8.6 | 1 | |||
| 18 | | T. Thomas | 36.4 | 10/1/1989 | vs | 32.4 | 34.4 | 105 | 21 | 5.0 | 1 | 99 | 4 | 24.8 | 1 | |||
| 19 |  | J. Cook III | 36.1 | 12/17/2023 | vs | 34.1 | 35.1 | 179 | 25 | 7.2 | 1 | 42 | 2 | 3 | 21.0 | 1 | ||
| 20 | | O.J. Simpson | 35.8 | 11/17/1975 | @ | 33.8 | 34.8 | 197 | 17 | 11.6 | 2 | 21 | 2 | 10.5 | 0 | |||
| 21 | | G. Bell | 35.8 | 11/18/1984 | vs | 33.8 | 34.8 | 206 | 27 | 7.6 | 1 | 12 | 2 | 6.0 | 1 | |||
| 22 | | T. Thomas | 35.7 | 12/20/1992 | @ | 29.7 | 32.7 | 115 | 24 | 4.8 | 2 | 62 | 6 | 10.3 | 0 | |||
| 23 | | T. Miller | 35.5 | 11/26/1978 | vs | 33.5 | 34.5 | 208 | 21 | 9.9 | 2 | 7 | 2 | 3.5 | 0 | |||
| 24 | | T. Thomas | 35.3 | 11/4/1990 | @ | 30.3 | 32.8 | 58 | 17 | 3.4 | 2 | 65 | 5 | 13.0 | 1 | |||
| 25 | | C. Gilchrist | 35.3 | 12/8/1962 | @ | 35.3 | 35.3 | 143 | 17 | 8.4 | 2 | 0 | 0 | 0 | ||||
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| AFC East | W | L | T | PCT |
|---|---|---|---|---|
 Patriots - y | 14 | 3 | 0 | .824 |
 Bills - w | 12 | 5 | 0 | .706 |
 Dolphins - e | 7 | 10 | 0 | .412 |
 Jets - e | 3 | 14 | 0 | .176 |
| AFC North | W | L | T | PCT |
 Steelers - y | 10 | 7 | 0 | .588 |
 Ravens - e | 8 | 9 | 0 | .471 |
 Bengals - e | 6 | 11 | 0 | .353 |
 Browns - e | 5 | 12 | 0 | .294 |
| AFC South | W | L | T | PCT |
 Jaguars - y | 13 | 4 | 0 | .765 |
 Texans - w | 12 | 5 | 0 | .706 |
 Colts - e | 8 | 9 | 0 | .471 |
 Titans - e | 3 | 14 | 0 | .176 |
| AFC West | W | L | T | PCT |
 Broncos - z* | 14 | 3 | 0 | .824 |
 Chargers - w | 11 | 6 | 0 | .647 |
 Chiefs - e | 6 | 11 | 0 | .353 |
 Raiders - e | 3 | 14 | 0 | .176 |
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
 Eagles - y | 11 | 6 | 0 | .647 |
 Cowboys - e | 7 | 9 | 1 | .441 |
 Commanders - e | 5 | 12 | 0 | .294 |
 Giants - e | 4 | 13 | 0 | .235 |
| NFC North | W | L | T | PCT |
 Bears - y | 11 | 6 | 0 | .647 |
 Packers - w | 9 | 7 | 1 | .559 |
 Vikings - e | 9 | 8 | 0 | .529 |
 Lions - e | 9 | 8 | 0 | .529 |
| NFC South | W | L | T | PCT |
 Panthers - y | 8 | 9 | 0 | .471 |
 Buccaneers - e | 8 | 9 | 0 | .471 |
 Falcons - e | 8 | 9 | 0 | .471 |
 Saints - e | 6 | 11 | 0 | .353 |
| NFC West | W | L | T | PCT |
 Seahawks - z* | 14 | 3 | 0 | .824 |
 Rams - w | 12 | 5 | 0 | .706 |
 49ers - w | 12 | 5 | 0 | .706 |
 Cardinals - e | 3 | 14 | 0 | .176 |