The San Francisco 49ers put up the most points by a team in a Week-1 game in 2021, with 41 points versus the Lions on September 12, 2021.
| TEAM | PTS | DATE | TM | OPP | RESULT | PASS TD | RUSH TD | RET TD | TD | FGM | XPM | XP2 | SFTY | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | 49ers | 41 | 9/12/2021 |  SF | @ |  DET | W 41-33 | 2 | 2 | 1 | 5 | 2 | 5 | 0 | 0 |
| 2 |  | Cardinals | 38 | 9/12/2021 |  ARI | @ |  TEN | W 38-13 | 4 | 1 | 0 | 5 | 1 | 5 | 0 | 0 |
| 3 |  | Saints | 38 | 9/12/2021 |  NO | vs |  GB | W 38-3 | 5 | 0 | 0 | 5 | 1 | 5 | 0 | 0 |
| 4 |  | Texans | 37 | 9/12/2021 |  HOU | vs |  JAX | W 37-21 | 2 | 2 | 0 | 4 | 3 | 4 | 0 | 0 |
| 5 |  | Rams | 34 | 9/12/2021 |  LAR | vs |  CHI | W 34-14 | 3 | 1 | 0 | 4 | 2 | 4 | 0 | 0 |
| 6 |  | Raiders | 33 | 9/13/2021 |  LV | vs |  BAL | W 33-27 | 2 | 2 | 0 | 4 | 2 | 3 | 0 | 0 |
| 7 |  | Lions | 33 | 9/12/2021 | DET | vs | SF | L 33-41 | 3 | 1 | 0 | 4 | 1 | 2 | 2 | 0 |
| 8 |  | Chiefs | 33 | 9/12/2021 |  KC | vs |  CLE | W 33-29 | 3 | 1 | 0 | 4 | 2 | 3 | 0 | 0 |
| 9 |  | Eagles | 32 | 9/12/2021 |  PHI | @ |  ATL | W 32-6 | 3 | 1 | 0 | 4 | 1 | 3 | 1 | 0 |
| 10 |  | Buccaneers | 31 | 9/9/2021 |  TB | vs |  DAL | W 31-29 | 4 | 0 | 0 | 4 | 1 | 4 | 0 | 0 |
| 11 |  | Browns | 29 | 9/12/2021 | CLE | @ | KC | L 29-33 | 0 | 4 | 0 | 4 | 0 | 3 | 1 | 0 |
| 12 |  | Cowboys | 29 | 9/9/2021 | DAL | @ | TB | L 29-31 | 3 | 0 | 0 | 3 | 3 | 2 | 0 | 0 |
| 13 |  | Seahawks | 28 | 9/12/2021 |  SEA | @ |  IND | W 28-16 | 4 | 0 | 0 | 4 | 0 | 4 | 0 | 0 |
| 14 |  | Ravens | 27 | 9/13/2021 | BAL | @ | LV | L 27-33 | 1 | 2 | 0 | 3 | 2 | 3 | 0 | 0 |
| 15 |  | Bengals | 27 | 9/12/2021 |  CIN | vs |  MIN | W 27-24 | 2 | 1 | 0 | 3 | 2 | 3 | 0 | 0 |
| 16 |  | Broncos | 27 | 9/12/2021 |  DEN | @ |  NYG | W 27-13 | 2 | 1 | 0 | 3 | 2 | 3 | 0 | 0 |
| 17 |  | Vikings | 24 | 9/12/2021 | MIN | @ | CIN | L 24-27 | 2 | 1 | 0 | 3 | 1 | 3 | 0 | 0 |
| 18 |  | Steelers | 23 | 9/12/2021 |  PIT | @ |  BUF | W 23-16 | 1 | 0 | 1 | 2 | 3 | 2 | 0 | 0 |
| 19 |  | Jaguars | 21 | 9/12/2021 | JAX | @ | HOU | L 21-37 | 3 | 0 | 0 | 3 | 0 | 3 | 0 | 0 |
| 20 |  | Chargers | 20 | 9/12/2021 |  LAC | @ |  WAS | W 20-16 | 1 | 1 | 0 | 2 | 2 | 2 | 0 | 0 |
| 21 |  | Panthers | 19 | 9/12/2021 |  CAR | vs |  NYJ | W 19-14 | 1 | 1 | 0 | 2 | 2 | 1 | 0 | 0 |
| 22 |  | Dolphins | 17 | 9/12/2021 |  MIA | @ |  NE | W 17-16 | 1 | 1 | 0 | 2 | 1 | 2 | 0 | 0 |
| 23 |  | Washington Football Team | 16 | 9/12/2021 | WAS | vs | LAC | L 16-20 | 1 | 0 | 0 | 1 | 3 | 1 | 0 | 0 |
| 24 |  | Colts | 16 | 9/12/2021 | IND | vs | SEA | L 16-28 | 2 | 0 | 0 | 2 | 1 | 1 | 0 | 0 |
| 25 |  | Bills | 16 | 9/12/2021 | BUF | vs | PIT | L 16-23 | 1 | 0 | 0 | 1 | 3 | 1 | 0 | 0 |
More 49ers Stats
Team Rankings
PPG
22.4
15th
OPP PPG
22.9
18th
RUSH YDS/G
133.5
8th
PASS YDS/G
240.9
15th
NFL 2024 Leaders
NFL 2024 Rankings
NFL Fantasy 2024
NFL 2024 Betting
NFL 2024 Division Standings
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
| Eagles | 11 | 2 | 0 | .846 |
 Commanders | 8 | 5 | 0 | .615 |
| NFC North | W | L | T | PCT |
| Lions | 12 | 1 | 0 | .923 |
| Vikings | 11 | 2 | 0 | .846 |
| NFC South | W | L | T | PCT |
| Buccaneers | 7 | 6 | 0 | .538 |
| Falcons | 6 | 7 | 0 | .462 |
| NFC West | W | L | T | PCT |
| Seahawks | 8 | 5 | 0 | .615 |
| Rams | 8 | 6 | 0 | .571 |
CHI 
