7 players were tied for the most tackles for loss in a game in 2022, with 4 tackles. The first three are Eric Kendricks on December 17, 2022, Daron Payne on November 6, 2022 and Za'Darius Smith on October 30, 2022.

Interpreted as:

most tfl by a player single regular-season game 2022

	NAME	TFL	DATE	TM		OPP	TKL	AST	COMB	SCK	SCKY	INT	INT YDS	INT TD	FF	FR	FR TD
1	Eric Kendricks E. Kendricks	4	12/17/2022	MIN	vs	IND	7	5	12	1.0	8	0	0	0	0	0	0
2	Daron Payne D. Payne	4	11/6/2022	WAS	vs	MIN	4	2	6	1.0	9	0	0	0	0	0	0
3	Za'Darius Smith Z. Smith	4	10/30/2022	MIN	vs	ARI	7	0	7	3.0	22	0	0	0	0	0	0
4	Jonathan Allen J. Allen	4	10/2/2022	WAS	@	DAL	5	3	8	1.0	6	0	0	0	0	0	0
5	Maxx Crosby M. Crosby	4	10/2/2022	LV	vs	DEN	4	0	4	2.0	16	0	0	0	0	0	0
6	Deatrich Wise Jr. D. Wise Jr.	4	9/25/2022	NE	vs	BAL	5	1	6	3.0	12	0	0	0	0	0	0
7	Frankie Luvu F. Luvu	4	9/18/2022	CAR	@	NYG	10	0	10	0.0	0	0	0	0	0	0	0
8	Justin Jones J. Jones	3	1/8/2023	CHI	vs	MIN	3	0	3	0.0	0	0	0	0	0	0	0
9	Quincy Williams Q. Williams	3	1/8/2023	NYJ	@	MIA	9	1	10	1.0	12	0	0	0	0	0	0
10	J.J. Watt	3	1/8/2023	ARI	@	SF	3	2	5	2.0	16	0	0	0	0	0	0
11	Frankie Luvu F. Luvu	3	1/1/2023	CAR	@	TB	10	3	13	1.0	7	0	0	0	0	0	0
12	Carl Granderson C. Granderson	3	12/24/2022	NO	@	CLE	5	1	6	1.0	7	0	0	0	0	0	0
13	Ogbo Okoronkwo O. Okoronkwo	3	12/24/2022	HOU	@	TEN	5	0	5	2.0	11	0	0	0	0	0	0
14	Cameron Heyward C. Heyward	3	12/24/2022	PIT	vs	LV	4	3	7	2.0	18	0	0	0	0	0	0
15	Josh Sweat J. Sweat	3	12/18/2022	PHI	@	CHI	5	1	6	2.0	21	0	0	0	0	0	0
16	Christian Harris C. Harris	3	12/18/2022	HOU	vs	KC	7	6	13	0.0	0	0	0	0	0	0	0
17	Dawuane Smoot D. Smoot	3	12/18/2022	JAX	vs	DAL	4	1	5	0.0	0	0	0	0	0	0	0
18	J.J. Watt	3	12/18/2022	ARI	@	DEN	4	1	5	3.0	20	0	0	0	1	0	0
19	Kayvon Thibodeaux K. Thibodeaux	3	12/18/2022	NYG	@	WAS	9	3	12	1.0	9	0	0	0	1	1	1
20	Joshua Uche J. Uche	3	12/12/2022	NE	@	ARI	4	1	5	3.0	17	0	0	0	0	0	0
21	Brandon Graham B. Graham	3	12/11/2022	PHI	@	NYG	4	0	4	3.0	15	0	0	0	1	0	0
22	Myles Garrett M. Garrett	3	12/11/2022	CLE	@	CIN	4	2	6	2.0	12	0	0	0	0	0	0
23	Bud Dupree B. Dupree	3	12/11/2022	TEN	vs	JAX	5	1	6	0.0	0	0	0	0	0	0	0
24	Quinnen Williams Q. Williams	3	12/4/2022	NYJ	@	MIN	4	1	5	1.0	8	0	0	0	0	0	0
25	Bobby Wagner B. Wagner	3	12/4/2022	LAR	vs	SEA	4	3	7	2.0	8	1	0	0	0	0	0

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StatMuse has game-level data for tackles for loss going back to the 2001 season.

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7 players were tied for the most tackles for loss in a game in 2022, with 4 tackles. The first three are Eric Kendricks on December 17, 2022, Daron Payne on November 6, 2022 and Za'Darius Smith on October 30, 2022.

Interpreted as:

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