Since 1980, the San Francisco 49ers, the Denver Broncos and the New England Patriots are tied for the most Week-1 wins, with 29 wins.
| TEAM | W | GP | L | T | TD | PTS | PPG | OPP PTS | OPP PPG | 1DWN | 3DWN% | 4DWN% | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | 49ers | 29 | 46 | 17 | 0 | 119 | 1,077 | 23.4 | 929 | 20.2 | 918 | ||
| 2 |  | Broncos | 29 | 46 | 17 | 0 | 116 | 1,055 | 22.9 | 889 | 19.3 | 922 | ||
| 3 |  | Patriots | 29 | 45 | 16 | 0 | 127 | 1,083 | 24.1 | 910 | 20.2 | 941 | ||
| 4 |  | Packers | 28 | 46 | 18 | 0 | 122 | 1,027 | 22.3 | 994 | 21.6 | 843 | ||
| 5 |  | Chiefs | 28 | 46 | 18 | 0 | 127 | 1,101 | 23.9 | 973 | 21.2 | 845 | ||
| 6 |  | Eagles | 27 | 46 | 19 | 0 | 127 | 1,083 | 23.5 | 909 | 19.8 | 933 | ||
| 7 |  | Steelers | 26 | 46 | 19 | 1 | 106 | 955 | 20.8 | 975 | 21.2 | 842 | ||
| 8 |  | Vikings | 26 | 46 | 20 | 0 | 115 | 1,006 | 21.9 | 880 | 19.1 | 853 | ||
| 9 |  | Cowboys | 25 | 46 | 21 | 0 | 123 | 1,066 | 23.2 | 921 | 20.0 | 955 | ||
| 10 |  | Chargers | 25 | 45 | 20 | 0 | 119 | 1,045 | 23.2 | 902 | 20.0 | 908 | ||
| 11 |  | Dolphins | 25 | 44 | 19 | 0 | 117 | 993 | 22.6 | 930 | 21.1 | 790 | ||
| 12 |  | Lions | 24 | 46 | 21 | 1 | 126 | 1,082 | 23.5 | 1,125 | 24.5 | 862 | ||
| 13 |  | Bears | 23 | 46 | 23 | 0 | 107 | 960 | 20.9 | 889 | 19.3 | 877 | ||
| 14 |  | Rams | 23 | 46 | 23 | 0 | 94 | 918 | 20.0 | 1,030 | 22.4 | 839 | ||
| 15 |  | Bills | 23 | 46 | 23 | 0 | 109 | 961 | 20.9 | 882 | 19.2 | 900 | ||
| 16 |  | Commanders | 22 | 46 | 24 | 0 | 111 | 973 | 21.2 | 967 | 21.0 | 902 | ||
| 17 |  | Raiders | 22 | 46 | 24 | 0 | 106 | 926 | 20.1 | 997 | 21.7 | 852 | ||
| 18 |  | Titans | 21 | 46 | 25 | 0 | 107 | 960 | 20.9 | 1,009 | 21.9 | 859 | ||
| 19 |  | Falcons | 21 | 46 | 25 | 0 | 104 | 962 | 20.9 | 1,031 | 22.4 | 890 | ||
| 20 |  | Saints | 21 | 46 | 25 | 0 | 118 | 1,066 | 23.2 | 1,102 | 24.0 | 866 | ||
| 21 |  | Seahawks | 21 | 46 | 25 | 0 | 96 | 834 | 18.1 | 893 | 19.4 | 787 | ||
| 22 |  | Buccaneers | 21 | 45 | 24 | 0 | 96 | 821 | 18.2 | 945 | 21.0 | 776 | ||
| 23 |  | Giants | 20 | 46 | 26 | 0 | 109 | 912 | 19.8 | 1,091 | 23.7 | 794 | ||
| 24 |  | Jets | 20 | 46 | 26 | 0 | 116 | 983 | 21.4 | 1,080 | 23.5 | 840 | ||
| 25 |  | Bengals | 19 | 45 | 26 | 0 | 93 | 861 | 19.1 | 979 | 21.8 | 821 | ||
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More 49ers Stats
Team Leaders 
PASS
2,167
Purdy
RUSH
1,202
McCaffrey
REC
924
McCaffrey
Team Rankings
PPG
25.7
10th
OPP PPG
21.8
13th
RUSH YDS/G
106.9
24th
PASS YDS/G
254.0
6th
NFL 2025 Leaders
NFL 2025 Rankings
NFL Fantasy 2025
NFL 2025 Betting
NFL 2025 Standings
| AFC East | W | L | T | PCT |
|---|---|---|---|---|
 Patriots - y | 14 | 3 | 0 | .824 |
 Bills - w | 12 | 5 | 0 | .706 |
 Dolphins - e | 7 | 10 | 0 | .412 |
 Jets - e | 3 | 14 | 0 | .176 |
| AFC North | W | L | T | PCT |
 Steelers - y | 10 | 7 | 0 | .588 |
 Ravens - e | 8 | 9 | 0 | .471 |
 Bengals - e | 6 | 11 | 0 | .353 |
 Browns - e | 5 | 12 | 0 | .294 |
| AFC South | W | L | T | PCT |
 Jaguars - y | 13 | 4 | 0 | .765 |
 Texans - w | 12 | 5 | 0 | .706 |
 Colts - e | 8 | 9 | 0 | .471 |
 Titans - e | 3 | 14 | 0 | .176 |
| AFC West | W | L | T | PCT |
 Broncos - z* | 14 | 3 | 0 | .824 |
 Chargers - w | 11 | 6 | 0 | .647 |
 Chiefs - e | 6 | 11 | 0 | .353 |
 Raiders - e | 3 | 14 | 0 | .176 |
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
 Eagles - y | 11 | 6 | 0 | .647 |
 Cowboys - e | 7 | 9 | 1 | .441 |
 Commanders - e | 5 | 12 | 0 | .294 |
 Giants - e | 4 | 13 | 0 | .235 |
| NFC North | W | L | T | PCT |
 Bears - y | 11 | 6 | 0 | .647 |
 Packers - w | 9 | 7 | 1 | .559 |
 Vikings - e | 9 | 8 | 0 | .529 |
 Lions - e | 9 | 8 | 0 | .529 |
| NFC South | W | L | T | PCT |
 Panthers - y | 8 | 9 | 0 | .471 |
 Buccaneers - e | 8 | 9 | 0 | .471 |
 Falcons - e | 8 | 9 | 0 | .471 |
 Saints - e | 6 | 11 | 0 | .353 |
| NFC West | W | L | T | PCT |
 Seahawks - z* | 14 | 3 | 0 | .824 |
 Rams - w | 12 | 5 | 0 | .706 |
 49ers - w | 12 | 5 | 0 | .706 |
 Cardinals - e | 3 | 14 | 0 | .176 |