Brandon Marshall has made the most receptions in a Week-16 game against the Bills, with 10 receptions on December 21, 2008.

Interpreted as:

most week 16 catches by a player against bills

	NAME	REC	DATE	TM		OPP	TRG	REC YDS	AVG	REC TD	RUSH YDS	ATT	YPC	RUSH TD
1	Brandon Marshall B. Marshall	10	12/21/2008	DEN	vs	BUF	16	129	12.9	0	0	0		0
2	Chad Johnson C. Johnson	9	12/24/2005	CIN	vs	BUF	15	117	13.0	1	0	0		0
3	Terry Kirby T. Kirby	9	12/19/1993	MIA	vs	BUF		148	16.4	1	6	1	6.0	0
4	Roddy White R. White	8	12/27/2009	ATL	vs	BUF	14	139	17.4	2	0	0		0
5	Lenvil Elliott L. Elliott	8	12/21/1980	SF	vs	BUF		66	8.3	0	47	12	3.9	0
6	Gerald Everett G. Everett	7	12/23/2023	LAC	vs	BUF	8	42	6.0	0	0	0		0
7	T.J. Houshmandzadeh	7	12/24/2005	CIN	vs	BUF	10	70	10.0	0	0	0		0
8	Laveranues Coles L. Coles	7	12/30/2001	NYJ	vs	BUF	11	99	14.1	0	20	1	20.0	0
9	Keyshawn Johnson K. Johnson	7	12/19/1998	NYJ	@	BUF		66	9.4	0	25	1	25.0	0
10	Mark Clayton M. Clayton	7	12/23/1990	MIA	@	BUF		89	12.7	1	0	0		0
11	William Andrews W. Andrews	7	12/18/1983	ATL	vs	BUF		49	7.0	1	158	28	5.6	2
12	Jakobi Meyers J. Meyers	6	12/26/2021	NE	vs	BUF	8	59	9.8	0	0	0		0
13	Julian Edelman J. Edelman	6	12/23/2018	NE	vs	BUF	10	70	11.7	1	0	0		0
14	Terry Glenn T. Glenn	6	12/17/2000	NE	@	BUF	11	70	11.7	0	0	0		0
15	Keenan McCardell K. McCardell	6	12/14/1997	JAX	@	BUF		94	15.7	0	0	0		0
16	Mark Ingram M. Ingram	6	12/19/1993	MIA	vs	BUF		80	13.3	2	0	0		0
17	Jim Jensen J. Jensen	6	12/23/1990	MIA	@	BUF		42	7.0	0	0	0		0
18	Al Toon A. Toon	6	12/23/1989	NYJ	vs	BUF		67	11.2	0	0	0		0
19	Tony Nathan T. Nathan	6	12/22/1985	MIA	vs	BUF		45	7.5	0	54	11	4.9	1
20	Earl Cooper E. Cooper	6	12/21/1980	SF	vs	BUF		28	4.7	0	90	15	6.0	1
21	Quinshon Judkins Q. Judkins	5	12/21/2025	CLE	vs	BUF	6	29	5.8	0	22	8	2.8	0
22	Kayshon Boutte K. Boutte	5	12/22/2024	NE	@	BUF	7	95	19.0	1	0	0		0
23	Joshua Palmer J. Palmer	5	12/23/2023	LAC	vs	BUF	8	47	9.4	0	0	0		0
24	Cole Kmet C. Kmet	5	12/24/2022	CHI	vs	BUF	6	27	5.4	0	0	0		0
25	Julian Edelman J. Edelman	5	12/21/2019	NE	vs	BUF	6	72	14.4	0	0	0		0

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Results may be incomplete. StatMuse has complete game-level data for receptions going back to the 1960 season.

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