Johnny Unitas has the most career wins by a quarterback against the 49ers, with 18 wins.

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Regular season

	NAME	W	GP	CMP	ATT	PCT	YDS	AVG	YDS/G	TD	INT	RTG	TD%	INT%	SCK	SCKY
1	Johnny Unitas J. Unitas	18	28	397	728	54.5	5,725	7.9	204.5	40	25	84.3	5.5	3.4
2	Russell Wilson R. Wilson	17	21	389	603	64.5	4,353	7.2	207.3	36	10	98.9	6.0	1.7	58	390
3	Bart Starr B. Starr	14	26	224	364	61.5	2,908	8.0	111.8	21	14	89.9	5.8	3.8
4	Roman Gabriel R. Gabriel	13	19	225	490	45.9	3,236	6.6	170.3	25	15	72.1	5.1	3.1
5	Matt Hasselbeck M. Hasselbeck	12	18	317	494	64.2	3,665	7.4	203.6	27	17	90.4	5.5	3.4	26	128
6	Steve Bartkowski S. Bartkowski	11	18	290	492	58.9	3,416	6.9	189.8	20	14	81.8	4.1	2.8
7	Kurt Warner K. Warner	10	14	307	473	64.9	3,807	8.0	271.9	24	14	94.3	5.1	3.0	30	209
8	Norm Van Brocklin N. Van Brocklin	10	18	199	370	53.8	2,730	7.4	151.7	20	20	73.1	5.4	5.4
9	Earl Morrall E. Morrall	9	15	93	188	49.5	1,422	7.6	94.8	10	11	68.2	5.3	5.9
10	Drew Brees D. Brees	8	11	277	413	67.1	3,087	7.5	280.6	28	7	104.7	6.8	1.7	12	69
11	Brett Favre B. Favre	8	9	188	310	60.6	2,246	7.2	249.6	14	10	84.4	4.5	3.2	15	98
12	Fran Tarkenton F. Tarkenton	8	17	229	427	53.6	3,192	7.5	187.8	23	17	79.3	5.4	4.0
13	Ed Brown E. Brown	8	15	105	209	50.2	1,536	7.3	102.4	7	11	63.8	3.3	5.3
14	Zeke Bratkowski Z. Bratkowski	8	17	81	151	53.6	1,082	7.2	63.6	5	8	65.6	3.3	5.3
15	Lamar McHan L. McHan	7	8	25	58	43.1	424	7.3	53.0	3	2	71.3	5.2	3.4
16	Billy Wade B. Wade	7	20	201	385	52.2	2,640	6.9	132.0	23	19	73.5	6.0	4.9
17	Bobby Layne B. Layne	7	16	184	389	47.3	2,496	6.4	156.0	15	21	58.6	3.9	5.4
18	Aaron Rodgers A. Rodgers	6	10	232	352	65.9	2,764	7.9	276.4	21	3	106.1	6.0	0.9	25	183
19	Eli Manning E. Manning	6	9	203	330	61.5	2,244	6.8	249.3	16	9	86.5	4.8	2.7	8	52
20	Steve Beuerlein S. Beuerlein	6	10	210	338	62.1	2,671	7.9	267.1	24	9	99.4	7.1	2.7	18	128
21	Vince Ferragamo V. Ferragamo	6	8	131	217	60.4	1,732	8.0	216.5	17	8	96.4	7.8	3.7
22	Pat Haden P. Haden	6	8	83	151	55.0	1,213	8.0	151.6	10	4	92.4	6.6	2.6
23	James Harris J. Harris	6	8	77	124	62.1	1,053	8.5	131.6	5	3	92.6	4.0	2.4
24	Milt Plum M. Plum	6	9	91	189	48.1	1,382	7.3	153.6	9	8	70.9	4.8	4.2
25	Carson Wentz C. Wentz	5	6	82	126	65.1	840	6.7	140.0	8	3	95.3	6.3	2.4	9	55

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More Colts Stats

Team Leaders

PASS

376

Jones

RUSH

190

Taylor

REC

109

Downs

Team Rankings

PPG

26.5

10th

OPP PPG

37.0

32nd

RUSH YDS/G

110.5

15th

PASS YDS/G

188.0

26th

2026 Division Standings

TEAM	W	L	PCT
Jaguars	1	1	.500
Colts	0	2	.000
Titans	0	2	.000
Texans	0	2	.000

Schedule

DATE	MATCHUP			TIME (ET)
Sun 9/27	HOU	@	IND	1:00 PM
Sun 10/4	IND	@	WAS	9:30 AM
Sun 10/11	IND	@	PIT	1:00 PM
Sun 10/18	TEN	@	IND	1:00 PM
Sun 10/25	IND	@	MIN	1:00 PM

Last Game

Colts

0 - 2

Final

Chiefs

2 - 0

Sun 20 Sep 2026

NFL 2026 Leaders

Pass Yards Leaders

662

Shough

648

Young

627

Stroud

Rush Yards Leaders

290

Walker

212

Henry

208

Gibbs

Rec Yards Leaders

277

Smith-Njigba

268

Olave

225

Kincaid

Pass TD Leaders

6

Young

6

Prescott

6

Goff

Rush TD Leaders

4

Taylor

4

Allen

4

Henry

Rec TD Leaders

4

Smith-Njigba

4

St. Brown

3

Watson

QB Rating Leaders

127.3

Lock

125.9

Dart

125.8

Allen

Sack Leaders

4.0

Rousseau

3.5

Watt

3.0

Hutchinson

NFL 2026 Rankings

PPG Rankings

38.5

35.5

32.0

31.0

Opp PPG Rankings

8.0

8.5

10.0

12.5

13.5

15.0

Total Yards Rankings

457.5

427.5

424.5

409.0

385.5

Rush Yards Rankings

212.5

186.0

157.0

155.0

144.5

142.5

Pass Yards Rankings

331.0

324.0

313.5

291.0

283.0

279.5

Sack Leaders

8.0

7.0

NFL Fantasy 2026

Fantasy RB Rankings

49

Henry

48.9

Walker

47.3

Taylor

Fantasy WR Rankings

51.7

Smith-Njigba

44.9

St. Brown

37.7

Lamb

Fantasy TE Rankings

28.5

Kincaid

25.6

McBride

23.2

Kelce

Fantasy K Rankings

31

McPherson

27

McLaughlin

24

Butker

NFL 2026 Betting

Best Record ATS

2-0

Worst Record ATS

0-2

NFL 2026 Standings

NFC East	W	L	T	PCT
Eagles	2	0	0	1.000
Giants	1	1	0	.500
Cowboys	1	1	0	.500
Commanders	0	2	0	.000
NFC North	W	L	T	PCT
Vikings	2	0	0	1.000
Lions	1	1	0	.500
Bears	1	1	0	.500
Packers	1	1	0	.500
NFC South	W	L	T	PCT
Panthers	1	1	0	.500
Saints	1	1	0	.500
Buccaneers	0	2	0	.000
Falcons	0	2	0	.000
NFC West	W	L	T	PCT
Seahawks	2	0	0	1.000
49ers	2	0	0	1.000
Rams	1	1	0	.500
Cardinals	1	1	0	.500

AFC East	W	L	T	PCT
Bills	2	0	0	1.000
Patriots	1	1	0	.500
Jets	1	1	0	.500
Dolphins	0	2	0	.000
AFC North	W	L	T	PCT
Bengals	2	0	0	1.000
Ravens	1	1	0	.500
Steelers	1	1	0	.500
Browns	1	1	0	.500
AFC South	W	L	T	PCT
Jaguars	1	1	0	.500
Titans	0	2	0	.000
Texans	0	2	0	.000
Colts	0	2	0	.000
AFC West	W	L	T	PCT
Chiefs	2	0	0	1.000
Raiders	2	0	0	1.000
Broncos	1	1	0	.500
Chargers	0	2	0	.000