The Buffalo Bills had their most all-purpose yards in a game in 2022 versus the Steelers on October 9, 2022, with 552 yards.
| TEAM | YDS | DATE | TM | OPP | RESULT | TD | PASS YDS | SCKY | PASS TD | RUSH YDS | RUSH TD | RET YDS | RET TD | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | Bills | 552 | 10/9/2022 | vs | W 38-3 | 5 | 432 | 0 | 4 | 120 | 1 | 36 | 0 | ||
| 2 | | Bills | 497 | 9/25/2022 | @ | L 19-21 | 2 | 400 | 18 | 2 | 115 | 0 | 49 | 0 | ||
| 3 | | Bills | 486 | 11/13/2022 | vs | L 30-33 | 3 | 330 | 19 | 1 | 175 | 2 | 182 | 0 | ||
| 4 | | Bills | 446 | 12/17/2022 | vs | W 32-29 | 4 | 304 | 8 | 4 | 150 | 0 | 76 | 0 | ||
| 5 | | Bills | 443 | 10/16/2022 | @ | W 24-20 | 3 | 329 | 11 | 3 | 125 | 0 | 32 | 0 | ||
| 6 | | Bills | 426 | 12/24/2022 | @ | W 35-13 | 5 | 172 | 0 | 2 | 254 | 3 | 96 | 0 | ||
| 7 | | Bills | 414 | 9/19/2022 | vs | W 41-7 | 5 | 317 | 4 | 4 | 101 | 0 | 41 | 1 | ||
| 8 | | Bills | 413 | 9/8/2022 | @ | W 31-10 | 4 | 297 | 5 | 3 | 121 | 1 | 20 | 0 | ||
| 9 | | Bills | 401 | 11/24/2022 | @ | W 28-25 | 3 | 253 | 16 | 2 | 164 | 1 | 26 | 0 | ||
| 10 | | Bills | 369 | 10/30/2022 | vs | W 27-17 | 3 | 218 | 2 | 2 | 153 | 1 | 89 | 0 | ||
| 11 | | Bills | 357 | 11/20/2022 | vs | W 31-23 | 2 | 197 | 11 | 1 | 171 | 1 | 113 | 0 | ||
| 12 | | Bills | 355 | 12/1/2022 | @ | W 24-10 | 3 | 223 | 0 | 2 | 132 | 1 | 30 | 0 | ||
| 13 | | Bills | 327 | 1/8/2023 | vs | W 35-23 | 5 | 254 | 17 | 3 | 90 | 0 | 241 | 2 | ||
| 14 | | Bills | 326 | 10/2/2022 | @ | W 23-20 | 2 | 213 | 12 | 1 | 125 | 1 | 53 | 0 | ||
| 15 | | Bills | 317 | 11/6/2022 | @ | L 17-20 | 2 | 205 | 22 | 0 | 134 | 2 | 18 | 0 | ||
| 16 | | Bills | 232 | 12/11/2022 | vs | W 20-12 | 2 | 147 | 17 | 1 | 102 | 1 | 82 | 0 |
CHI
NYJMore Bills Stats
Team Leaders 
PASS
3,668
Allen
RUSH
1,621
Cook
REC
719
Shakir
Team Rankings
PPG
28.3
4th
OPP PPG
21.5
12th
RUSH YDS/G
159.6
1st
PASS YDS/G
234.2
13th
NFL 2025 Leaders
NFL 2025 Rankings
NFL Fantasy 2025
NFL 2025 Betting
NFL 2025 Standings
| AFC East | W | L | T | PCT |
|---|---|---|---|---|
 Patriots - y | 14 | 3 | 0 | .824 |
 Bills - w | 12 | 5 | 0 | .706 |
 Dolphins - e | 7 | 10 | 0 | .412 |
 Jets - e | 3 | 14 | 0 | .176 |
| AFC North | W | L | T | PCT |
 Steelers - y | 10 | 7 | 0 | .588 |
 Ravens - e | 8 | 9 | 0 | .471 |
 Bengals - e | 6 | 11 | 0 | .353 |
 Browns - e | 5 | 12 | 0 | .294 |
| AFC South | W | L | T | PCT |
 Jaguars - y | 13 | 4 | 0 | .765 |
 Texans - w | 12 | 5 | 0 | .706 |
 Colts - e | 8 | 9 | 0 | .471 |
 Titans - e | 3 | 14 | 0 | .176 |
| AFC West | W | L | T | PCT |
 Broncos - z* | 14 | 3 | 0 | .824 |
 Chargers - w | 11 | 6 | 0 | .647 |
 Chiefs - e | 6 | 11 | 0 | .353 |
 Raiders - e | 3 | 14 | 0 | .176 |
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
 Eagles - y | 11 | 6 | 0 | .647 |
 Cowboys - e | 7 | 9 | 1 | .441 |
 Commanders - e | 5 | 12 | 0 | .294 |
 Giants - e | 4 | 13 | 0 | .235 |
| NFC North | W | L | T | PCT |
 Bears - y | 11 | 6 | 0 | .647 |
 Packers - w | 9 | 7 | 1 | .559 |
 Vikings - e | 9 | 8 | 0 | .529 |
 Lions - e | 9 | 8 | 0 | .529 |
| NFC South | W | L | T | PCT |
 Panthers - y | 8 | 9 | 0 | .471 |
 Buccaneers - e | 8 | 9 | 0 | .471 |
 Falcons - e | 8 | 9 | 0 | .471 |
 Saints - e | 6 | 11 | 0 | .353 |
| NFC West | W | L | T | PCT |
 Seahawks - z* | 14 | 3 | 0 | .824 |
 Rams - w | 12 | 5 | 0 | .706 |
 49ers - w | 12 | 5 | 0 | .706 |
 Cardinals - e | 3 | 14 | 0 | .176 |
