The San Francisco 49ers had their most interception-return yards in a game against the St. Louis Rams on November 26, 1995, with 171 yards.

Interpreted as:

most yards interceptions in a regular-season game for the 49ers

	TEAM	INT YDS	DATE	TM		OPP	RESULT	TKL	AST	COMB	SCK	SCKY	INT	INT TD	FF	FR	FR TD
1	49ers	171	11/26/1995	SF	vs	STL	W 41-13				1.0	2	4	1		1	0
2	49ers	163	10/26/1986	SF	@	GB	W 31-17				3.0	33	3	2		1	0
3	49ers	126	10/4/1981	SF	@	WAS	W 30-17				2.0	20	4	1		2	1
4	49ers	117	11/22/1993	SF	vs	NO	W 42-7				4.0	26	4	1		0	0
5	49ers	115	12/3/2000	SF	@	SD	W 45-17				2.0	12	4	1		1	0
6	49ers	115	10/16/1994	SF	@	ATL	W 42-3				6.0	40	4	1		2	1
7	49ers	113	9/14/1997	SF	vs	NO	W 33-7				1.0	9	6	0		2	0
8	49ers	110	12/15/1997	SF	vs	DEN	W 34-17				1.0	9	2	1		1	1
9	49ers	106	11/28/1971	SF	@	NYJ	W 24-21				0.0	0	2	0		1	0
10	49ers	104	9/8/1983	SF	@	MIN	W 48-17				4.0	33	5	1		1	0
11	49ers	100	12/24/2017	SF	vs	JAX	W 44-33	55	15	70	1.0	2	3	1	0	0	0
12	49ers	98	9/16/1984	SF	vs	NO	W 30-20				2.0	13	5	0		0	0
13	49ers	97	10/28/2001	SF	@	CHI	L 31-37	67	4	71	0.0	0	2	1	1	1	1
14	49ers	96	11/9/1986	SF	vs	STL	W 43-17				1.0	7	3	1		1	0
15	49ers	96	11/24/1968	SF	@	PIT	W 45-28				1.0	7	5	2		0	0
16	49ers	94	1/2/2011	SF	vs	ARI	W 38-7	56	22	78	6.0	41	2	1	2	0	0
17	49ers	94	12/11/1966	SF	vs	CHI	W 41-14				4.0	42	3	1		1	1
18	49ers	92	11/25/2012	SF	@	NO	W 31-21	45	20	65	5.0	36	2	2	0	0	0
19	49ers	91	11/6/1994	SF	@	WAS	W 37-22				3.0	18	2	1		1	0
20	49ers	91	10/1/1961	SF	@	DET	W 49-0				2.0	18	4	0		2	0
21	49ers	90	11/12/2009	SF	vs	CHI	W 10-6	45	16	61	0.0	0	5	0	0	0	0
22	49ers	90	12/11/1994	SF	@	SD	W 38-15				2.0	15	2	1		0	0
23	49ers	89	12/23/2013	SF	vs	ATL	W 34-24	56	13	69	1.0	7	2	1	0	0	0
24	49ers	89	12/19/1983	SF	vs	DAL	W 42-17				3.0	25	3	1		2	0
25	49ers	88	11/1/1970	SF	vs	GB	W 26-10				2.0	20	4	0		2	0

Unlock 2x data

Results may be incomplete. StatMuse has complete team, game-level data for interception yards going back to the 1960 season.

More 49ers Stats

Team Leaders

PASS

2,167

Purdy

RUSH

1,202

McCaffrey

REC

924

McCaffrey

Team Rankings

PPG

25.7

10th

OPP PPG

21.8

13th

RUSH YDS/G

106.9

24th

PASS YDS/G

254.0

6th

2025 Division Standings

TEAM	W	L	PCT
Seahawks	14	3	.824
Rams	12	5	.706
49ers	12	5	.706
Cardinals	3	14	.176

Last Game

49ers

1 - 1

Final

Seahawks

1 - 0

Sat 17 Jan 2026

NFL 2025 Leaders

Pass Yards Leaders

4,707

Stafford

4,564

Goff

4,552

Prescott

Rush Yards Leaders

1,621

Cook

1,595

Henry

1,585

Taylor

Rec Yards Leaders

1,793

Smith-Njigba

1,715

Nacua

1,429

Pickens

Pass TD Leaders

46

Stafford

34

Goff

31

Maye

Rush TD Leaders

18

Taylor

16

Henry

14

Allen

Rec TD Leaders

14

Adams

11

McBride

11

St. Brown

QB Rating Leaders

113.5

Maye

109.2

Stafford

105.5

Goff

Sack Leaders

23.0

Garrett

16.5

Burns

15.0

Hunter

NFL 2025 Rankings

PPG Rankings

30.5

28.8

28.4

28.3

27.9

Opp PPG Rankings

17.2

17.4

18.3

18.8

19.1

19.3

Total Yards Rankings

394.6

391.9

379.4

376.3

373.2

369.5

Rush Yards Rankings

159.6

156.6

144.5

134.7

129.1

128.9

Pass Yards Rankings

278.5

276.9

268.6

262.3

256.1

254.0

Sack Leaders

68.0

57.0

53.0

49.0

48.0

NFL Fantasy 2025

Fantasy RB Rankings

316.3

Taylor

314.6

McCaffrey

291.8

Robinson

Fantasy WR Rankings

246

Nacua

240.9

Smith-Njigba

207

St. Brown

Fantasy TE Rankings

189.9

McBride

125.1

Goedert

122.8

Pitts

Fantasy K Rankings

202

Myers

194

Fairbairn

187.6

Aubrey

NFL 2025 Betting

Best Record ATS

15-5

12-6

14-7

12-6-1

12-7

11-7

Worst Record ATS

5-12

5-12-1

6-11

7-10

NFL 2025 Standings

AFC East	W	L	T	PCT
Patriots - y	14	3	0	.824
Bills - w	12	5	0	.706
Dolphins - e	7	10	0	.412
Jets - e	3	14	0	.176
AFC North	W	L	T	PCT
Steelers - y	10	7	0	.588
Ravens - e	8	9	0	.471
Bengals - e	6	11	0	.353
Browns - e	5	12	0	.294
AFC South	W	L	T	PCT
Jaguars - y	13	4	0	.765
Texans - w	12	5	0	.706
Colts - e	8	9	0	.471
Titans - e	3	14	0	.176
AFC West	W	L	T	PCT
Broncos - z*	14	3	0	.824
Chargers - w	11	6	0	.647
Chiefs - e	6	11	0	.353
Raiders - e	3	14	0	.176

NFC East	W	L	T	PCT
Eagles - y	11	6	0	.647
Cowboys - e	7	9	1	.441
Commanders - e	5	12	0	.294
Giants - e	4	13	0	.235
NFC North	W	L	T	PCT
Bears - y	11	6	0	.647
Packers - w	9	7	1	.559
Vikings - e	9	8	0	.529
Lions - e	9	8	0	.529
NFC South	W	L	T	PCT
Panthers - y	8	9	0	.471
Buccaneers - e	8	9	0	.471
Falcons - e	8	9	0	.471
Saints - e	6	11	0	.353
NFC West	W	L	T	PCT
Seahawks - z*	14	3	0	.824
Rams - w	12	5	0	.706
49ers - w	12	5	0	.706
Cardinals - e	3	14	0	.176