The San Francisco 49ers had a 6-4 record against the spread in the NFC against the AFC West at home between the 2002 and 2021 seasons.

	TEAM	ATS	ATS COV %	ATS AVG	O/U REC	O/U AVG	GP	W	L	TD	PTS	PPG	OPP PTS	OPP PPG	1DWN	3DWN%	4DWN%
1	49ers	6-4	60	+2.1	3-7	+0.7	10	7	3	27	236	23.6	202	20.2	191	44.4	28.6
2	Cardinals	2-7-1	20	-4	7-3	+5	10	4	6	23	208	20.8	259	25.9	171	32.4	71.4
3	Rams	6-3-1	60	+8.8	4-5-1	+1.3	10	8	2	33	287	28.7	203	20.3	217	36.9	60.0
4	Seahawks	6-4	60	-0.7	5-5	+3.7	10	6	4	27	243	24.3	245	24.5	212	38.7	50.0
5	Buccaneers	6-4-1	50	+2.4	8-4	+8.5	12	6	6	43	339	28.3	298	24.8	232	37.1	50.0
6	Bears	5-4-1	50	-0.5	3-7	-3.9	10	6	4	18	191	19.1	182	18.2	193	36.4	46.2
7	Packers	8-2	80	+9.3	7-2-1	+10.5	10	9	1	46	363	36.3	201	20.1	210	43.9	16.7
8	Vikings	7-3	70	+7.3	8-2	+6.9	10	8	2	37	298	29.8	202	20.2	215	40.0	62.5
9	Lions	7-3	70	+10.4	4-6	-6.1	10	7	3	29	258	25.8	148	14.8	199	39.1	66.7
10	Falcons	5-5	50	+4.7	4-5-1	+2.4	10	7	3	34	299	29.9	204	20.4	211	48.1	20.0
11	Panthers	4-6	40	-1	4-6	-2.4	10	4	6	24	227	22.7	198	19.8	200	41.8	44.4
12	Saints	4-6	40	+0.4	5-5	+3.6	10	5	5	34	282	28.2	259	25.9	210	39.8	55.6
13	Eagles	2-7	20	-0.8	6-4	+4.9	10	6	4	32	277	27.7	239	23.9	221	38.9	45.5
14	Giants	4-6	40	+0.8	4-5-1	-1.1	10	6	4	26	232	23.2	208	20.8	210	40.6	40.0
15	Washington Football Team	4-6	40	-2.4	3-7	-4.9	10	4	6	19	186	18.6	211	21.1	164	39.2	28.6
16	Cowboys	3-6-1	30	-5.1	5-5	+4.3	10	4	6	33	255	25.5	265	26.5	206	44.2	28.6

StatMuse has team, game-level data for spread records going back to the 1979 season.

More 49ers Stats

Team Leaders

PASS

2,167

Purdy

RUSH

1,202

McCaffrey

REC

924

McCaffrey

Team Rankings

PPG

25.7

10th

OPP PPG

21.8

13th

RUSH YDS/G

106.9

24th

PASS YDS/G

254.0

6th

2025 Division Standings

TEAM	W	L	PCT
Seahawks	14	3	.824
Rams	12	5	.706
49ers	12	5	.706
Cardinals	3	14	.176

Last Game

49ers

1 - 1

Final

Seahawks

1 - 0

Sat 17 Jan 2026

NFL 2025 Leaders

Pass Yards Leaders

4,707

Stafford

4,564

Goff

4,552

Prescott

Rush Yards Leaders

1,621

Cook

1,595

Henry

1,585

Taylor

Rec Yards Leaders

1,793

Smith-Njigba

1,715

Nacua

1,429

Pickens

Pass TD Leaders

46

Stafford

34

Goff

31

Maye

Rush TD Leaders

18

Taylor

16

Henry

14

Allen

Rec TD Leaders

14

Adams

11

McBride

11

St. Brown

QB Rating Leaders

113.5

Maye

109.2

Stafford

105.5

Goff

Sack Leaders

23.0

Garrett

16.5

Burns

15.0

Hunter

NFL 2025 Rankings

PPG Rankings

30.5

28.8

28.4

28.3

27.9

Opp PPG Rankings

17.2

17.4

18.3

18.8

19.1

19.3

Total Yards Rankings

394.6

391.9

379.4

376.3

373.2

369.5

Rush Yards Rankings

159.6

156.6

144.5

134.7

129.1

128.9

Pass Yards Rankings

278.5

276.9

268.6

262.3

256.1

254.0

Sack Leaders

68.0

57.0

53.0

49.0

48.0

NFL Fantasy 2025

Fantasy RB Rankings

316.3

Taylor

314.6

McCaffrey

291.8

Robinson

Fantasy WR Rankings

246

Nacua

240.9

Smith-Njigba

207

St. Brown

Fantasy TE Rankings

189.9

McBride

125.1

Goedert

122.8

Pitts

Fantasy K Rankings

202

Myers

194

Fairbairn

187.6

Aubrey

NFL 2025 Betting

Best Record ATS

15-5

12-6

14-7

12-6-1

12-7

11-7

Worst Record ATS

5-12

5-12-1

6-11

7-10

NFL 2025 Standings

AFC East	W	L	T	PCT
Patriots - y	14	3	0	.824
Bills - w	12	5	0	.706
Dolphins - e	7	10	0	.412
Jets - e	3	14	0	.176
AFC North	W	L	T	PCT
Steelers - y	10	7	0	.588
Ravens - e	8	9	0	.471
Bengals - e	6	11	0	.353
Browns - e	5	12	0	.294
AFC South	W	L	T	PCT
Jaguars - y	13	4	0	.765
Texans - w	12	5	0	.706
Colts - e	8	9	0	.471
Titans - e	3	14	0	.176
AFC West	W	L	T	PCT
Broncos - z*	14	3	0	.824
Chargers - w	11	6	0	.647
Chiefs - e	6	11	0	.353
Raiders - e	3	14	0	.176

NFC East	W	L	T	PCT
Eagles - y	11	6	0	.647
Cowboys - e	7	9	1	.441
Commanders - e	5	12	0	.294
Giants - e	4	13	0	.235
NFC North	W	L	T	PCT
Bears - y	11	6	0	.647
Packers - w	9	7	1	.559
Vikings - e	9	8	0	.529
Lions - e	9	8	0	.529
NFC South	W	L	T	PCT
Panthers - y	8	9	0	.471
Buccaneers - e	8	9	0	.471
Falcons - e	8	9	0	.471
Saints - e	6	11	0	.353
NFC West	W	L	T	PCT
Seahawks - z*	14	3	0	.824
Rams - w	12	5	0	.706
49ers - w	12	5	0	.706
Cardinals - e	3	14	0	.176