The New Orleans Saints had the highest point differential by a team in a Week-1 game in 2021, with a 35-point differential against the Packers on September 12, 2021.
| TEAM | DIFF | DATE | TM | OPP | RESULT | TD | 1DWN | OFF | OPP OFF | 3DWN% | 4DWN% | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | Saints | 35 | 9/12/2021 | vs | W 38-3 | 5 | 22 | 322 | 229 | 50.0 | 100.0 | ||
| 2 |  | Eagles | 26 | 9/12/2021 | @ | W 32-6 | 4 | 24 | 434 | 260 | 46.2 | 0.0 | ||
| 3 |  | Cardinals | 25 | 9/12/2021 | @ | W 38-13 | 5 | 22 | 416 | 248 | 53.8 | |||
| 4 |  | Rams | 20 | 9/12/2021 | vs | W 34-14 | 4 | 18 | 386 | 322 | 54.5 | 100.0 | ||
| 5 |  | Texans | 16 | 9/12/2021 | vs | W 37-21 | 4 | 22 | 449 | 395 | 57.1 | |||
| 6 |  | Broncos | 14 | 9/12/2021 | @ | W 27-13 | 3 | 24 | 420 | 314 | 46.7 | 100.0 | ||
| 7 |  | Seahawks | 12 | 9/12/2021 | @ | W 28-16 | 4 | 18 | 381 | 336 | 44.4 | |||
| 8 |  | 49ers | 8 | 9/12/2021 | @ | W 41-33 | 5 | 21 | 442 | 430 | 33.3 | |||
| 9 |  | Steelers | 7 | 9/12/2021 | @ | W 23-16 | 2 | 16 | 252 | 371 | 33.3 | |||
| 10 |  | Raiders | 6 | 9/13/2021 | vs | W 33-27 | 4 | 26 | 491 | 406 | 46.7 | 0.0 | ||
| 11 |  | Panthers | 5 | 9/12/2021 | vs | W 19-14 | 2 | 18 | 381 | 252 | 28.6 | 0.0 | ||
| 12 |  | Chargers | 4 | 9/12/2021 | @ | W 20-16 | 2 | 27 | 424 | 259 | 73.7 | |||
| 13 |  | Chiefs | 4 | 9/12/2021 | vs | W 33-29 | 4 | 21 | 397 | 457 | 69.2 | |||
| 14 |  | Bengals | 3 | 9/12/2021 | vs | W 27-24 | 3 | 20 | 366 | 403 | 21.4 | 66.7 | ||
| 15 |  | Buccaneers | 2 | 9/9/2021 | vs | W 31-29 | 4 | 24 | 431 | 451 | 45.5 | |||
| 16 |  | Dolphins | 1 | 9/12/2021 | @ | W 17-16 | 2 | 16 | 259 | 393 | 36.4 | |||
| 17 |  | Patriots | -1 | 9/12/2021 | vs | L 16-17 | 1 | 24 | 393 | 259 | 68.8 | |||
| 18 |  | Cowboys | -2 | 9/9/2021 | @ | L 29-31 | 3 | 30 | 451 | 431 | 52.9 | |||
| 19 |  | Vikings | -3 | 9/12/2021 | @ | L 24-27 | 3 | 24 | 403 | 366 | 37.5 | 100.0 | ||
| 20 |  | Washington Football Team | -4 | 9/12/2021 | vs | L 16-20 | 1 | 15 | 259 | 424 | 30.0 | 100.0 | ||
| 21 |  | Browns | -4 | 9/12/2021 | @ | L 29-33 | 4 | 24 | 457 | 397 | 28.6 | 75.0 | ||
| 22 |  | Jets | -5 | 9/12/2021 | @ | L 14-19 | 2 | 16 | 252 | 381 | 30.8 | 50.0 | ||
| 23 |  | Ravens | -6 | 9/13/2021 | @ | L 27-33 | 3 | 20 | 406 | 491 | 25.0 | 50.0 | ||
| 24 |  | Bills | -7 | 9/12/2021 | vs | L 16-23 | 1 | 22 | 371 | 252 | 44.4 | 33.3 | ||
| 25 |  | Lions | -8 | 9/12/2021 | vs | L 33-41 | 4 | 31 | 430 | 442 | 26.7 | 40.0 | ||
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More Saints Stats
Team Leaders 
PASS
2,384
Shough
RUSH
471
Kamara
REC
1,163
Olave
Team Rankings
PPG
18.0
28th
OPP PPG
22.5
16th
RUSH YDS/G
94.3
28th
PASS YDS/G
236.9
10th
2025 Division Standings
| TEAM | W | L | T | PCT |
|---|---|---|---|---|
8 | 9 | 0 | .471 | |
8 | 9 | 0 | .471 | |
8 | 9 | 0 | .471 | |
 Saints | 6 | 11 | 0 | .353 |
NFL 2025 Leaders
NFL 2025 Rankings
NFL Fantasy 2025
NFL 2025 Betting
NFL 2025 Standings
| AFC East | W | L | T | PCT |
|---|---|---|---|---|
 Patriots - y | 14 | 3 | 0 | .824 |
 Bills - w | 12 | 5 | 0 | .706 |
 Dolphins - e | 7 | 10 | 0 | .412 |
 Jets - e | 3 | 14 | 0 | .176 |
| AFC North | W | L | T | PCT |
 Steelers - y | 10 | 7 | 0 | .588 |
 Ravens - e | 8 | 9 | 0 | .471 |
 Bengals - e | 6 | 11 | 0 | .353 |
 Browns - e | 5 | 12 | 0 | .294 |
| AFC South | W | L | T | PCT |
 Jaguars - y | 13 | 4 | 0 | .765 |
 Texans - w | 12 | 5 | 0 | .706 |
 Colts - e | 8 | 9 | 0 | .471 |
 Titans - e | 3 | 14 | 0 | .176 |
| AFC West | W | L | T | PCT |
 Broncos - z* | 14 | 3 | 0 | .824 |
 Chargers - w | 11 | 6 | 0 | .647 |
 Chiefs - e | 6 | 11 | 0 | .353 |
 Raiders - e | 3 | 14 | 0 | .176 |
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
 Eagles - y | 11 | 6 | 0 | .647 |
 Cowboys - e | 7 | 9 | 1 | .441 |
 Commanders - e | 5 | 12 | 0 | .294 |
 Giants - e | 4 | 13 | 0 | .235 |
| NFC North | W | L | T | PCT |
 Bears - y | 11 | 6 | 0 | .647 |
 Packers - w | 9 | 7 | 1 | .559 |
 Vikings - e | 9 | 8 | 0 | .529 |
 Lions - e | 9 | 8 | 0 | .529 |
| NFC South | W | L | T | PCT |
 Panthers - y | 8 | 9 | 0 | .471 |
 Buccaneers - e | 8 | 9 | 0 | .471 |
 Falcons - e | 8 | 9 | 0 | .471 |
| Saints - e | 6 | 11 | 0 | .353 |
| NFC West | W | L | T | PCT |
 Seahawks - z* | 14 | 3 | 0 | .824 |
 Rams - w | 12 | 5 | 0 | .706 |
 49ers - w | 12 | 5 | 0 | .706 |
 Cardinals - e | 3 | 14 | 0 | .176 |