The San Francisco 49ers have a 34-35 record against the AFC West in the regular-season and playoffs all-time.
| TEAM | DATE | REC | TM | OPP | RESULT | W% | TD | 1DWN | OFF | OPP OFF | 3DWN% | 4DWN% | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | 49ers | 10/25/1970 | 1-0 | vs | W 19-14 | 1.000 | 1 | 16 | 362 | 283 | ||||
| 2 | | 49ers | 12/20/1970 | 1-0 | @ | W 38-7 | 1.000 | 5 | 16 | 296 | 358 | ||||
| 3 | | 49ers | 12/6/1971 | 0-1 | vs | L 17-26 | .000 | 2 | 18 | 331 | 427 | ||||
| 4 | | 49ers | 9/17/1972 | 1-0 | vs | W 34-3 | 1.000 | 4 | 18 | 295 | 258 | ||||
| 5 | | 49ers | 9/23/1973 | 1-0 | @ | W 36-34 | 1.000 | 3 | 16 | 347 | 355 | ||||
| 6 | | 49ers | 10/27/1974 | 0-1 | vs | L 24-35 | .000 | 3 | 20 | 372 | 297 | ||||
| 7 | | 49ers | 10/5/1975 | 1-0 | @ | W 20-3 | 1.000 | 2 | 15 | 215 | 212 | ||||
| 8 | | 49ers | 12/5/1976 | 0-1 | @ | L 7-13 | .000 | 1 | 18 | 281 | 267 | ||||
| 9 | | 49ers | 9/30/1979 | 0-1 | @ | L 9-31 | .000 | 1 | 14 | 242 | 317 | ||||
| 10 | | 49ers | 10/7/1979 | 0-1 | vs | L 24-35 | .000 | 3 | 29 | 464 | 310 | ||||
| 11 | | 49ers | 11/4/1979 | 0-1 | @ | L 10-23 | .000 | 1 | 19 | 363 | 309 | ||||
| 12 | | 49ers | 11/18/1979 | 0-1 | vs | L 28-38 | .000 | 4 | 18 | 240 | 369 | ||||
| 13 | | 49ers | 9/12/1982 | 0-1 | vs | L 17-23 | .000 | 2 | 18 | 252 | 255 | ||||
| 14 | | 49ers | 9/19/1982 | 0-1 | @ | L 21-24 | .000 | 3 | 20 | 413 | 283 | ||||
| 15 | | 49ers | 12/11/1982 | 0-1 | vs | L 37-41 | .000 | 5 | 29 | 465 | 538 | ||||
| 16 | | 49ers | 12/26/1982 | 1-0 | @ | W 26-13 | 1.000 | 2 | 23 | 370 | 275 | ||||
| 17 | | 49ers | 9/22/1985 | 1-0 | @ | W 34-10 | 1.000 | 4 | 17 | 352 | 280 | ||||
| 18 | | 49ers | 11/11/1985 | 0-1 | @ | L 16-17 | .000 | 1 | 16 | 341 | 336 | ||||
| 19 | | 49ers | 11/17/1985 | 1-0 | vs | W 31-3 | 1.000 | 4 | 24 | 417 | 200 | ||||
| 20 | | 49ers | 11/25/1985 | 1-0 | vs | W 19-6 | 1.000 | 2 | 21 | 376 | 252 | ||||
| 21 | | 49ers | 9/25/1988 | 1-0 | @ | W 38-7 | 1.000 | 5 | 27 | 580 | 154 | ||||
| 22 | | 49ers | 10/9/1988 | 0-1 | vs | L 13-16 | .000 | 1 | 21 | 417 | 314 | ||||
| 23 | | 49ers | 11/13/1988 | 0-1 | vs | L 3-9 | .000 | 0 | 15 | 219 | 251 | ||||
| 24 | | 49ers | 11/27/1988 | 1-0 | @ | W 48-10 | 1.000 | 6 | 24 | 475 | 312 | ||||
| 25 | | 49ers | 1/28/1990 | 1-0 | @ | W 55-10 | 1.000 | 8 | 28 | 461 | 167 | ||||
| Average | .493 | 2.7 | 20.2 | 357.1 | 321.7 | ||||||||||
| Total | 34-35 | .493 | 188 | 1,395 | 24,638 | 22,198 | |||||||||
More 49ers Stats
Team Leaders 
PASS
2,151
Jones
RUSH
1,039
McCaffrey
REC
849
McCaffrey
Team Rankings
PPG
26.1
9th
OPP PPG
21.3
11th
RUSH YDS/G
104.3
24th
PASS YDS/G
259.2
5th
NFL 2025 Leaders
NFL 2025 Rankings
NFL Fantasy 2025
NFL 2025 Betting
NFL 2025 Standings
| AFC East | W | L | T | PCT |
|---|---|---|---|---|
 Patriots - x | 12 | 3 | 0 | .800 |
 Bills - x | 11 | 4 | 0 | .733 |
 Dolphins - e | 6 | 9 | 0 | .400 |
 Jets - e | 3 | 12 | 0 | .200 |
| AFC North | W | L | T | PCT |
9 | 6 | 0 | .600 | |
7 | 8 | 0 | .467 | |
 Bengals - e | 5 | 10 | 0 | .333 |
 Browns - e | 3 | 12 | 0 | .200 |
| AFC South | W | L | T | PCT |
 Jaguars - x | 11 | 4 | 0 | .733 |
10 | 5 | 0 | .667 | |
8 | 7 | 0 | .533 | |
 Titans - e | 3 | 12 | 0 | .200 |
| AFC West | W | L | T | PCT |
 Broncos - x | 12 | 3 | 0 | .800 |
 Chargers - x | 11 | 4 | 0 | .733 |
 Chiefs - e | 6 | 9 | 0 | .400 |
 Raiders - e | 2 | 13 | 0 | .133 |
Steelers
Ravens
Texans
Colts| NFC East | W | L | T | PCT |
|---|---|---|---|---|
 Eagles - y | 10 | 5 | 0 | .667 |
 Cowboys - e | 6 | 8 | 1 | .433 |
 Commanders - e | 4 | 11 | 0 | .267 |
 Giants - e | 2 | 13 | 0 | .133 |
| NFC North | W | L | T | PCT |
 Bears - x | 11 | 4 | 0 | .733 |
9 | 5 | 1 | .633 | |
8 | 7 | 0 | .533 | |
 Vikings - e | 7 | 8 | 0 | .467 |
| NFC South | W | L | T | PCT |
8 | 7 | 0 | .533 | |
7 | 8 | 0 | .467 | |
 Falcons - e | 6 | 9 | 0 | .400 |
 Saints - e | 5 | 10 | 0 | .333 |
| NFC West | W | L | T | PCT |
 Seahawks - x | 12 | 3 | 0 | .800 |
 49ers - x | 11 | 4 | 0 | .733 |
 Rams - x | 11 | 4 | 0 | .733 |
 Cardinals - e | 3 | 12 | 0 | .200 |
Packers
Lions
Panthers
Buccaneers
