Patrick Mahomes rushed for his most yards in a game versus the Eagles on September 14, with 66 yards.
Interpreted as:
Patrick Mahomes most rushing yards in a regular-season game| NAME | RUSH YDS | DATE | TM | OPP | ATT | YPC | RUSH TD | REC YDS | REC | TRG | AVG | REC TD | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | P. Mahomes | 66 | 9/14/2025 |  KC | vs |  PHI | 7 | 9.4 | 1 | 0 | 0 | 0 | 0 | |
| 2 | | P. Mahomes | 63 | 11/6/2022 | KC | vs |  TEN | 6 | 10.5 | 1 | 0 | 0 | 0 | 0 | |
| 3 | | P. Mahomes | 61 | 10/10/2021 | KC | vs |  BUF | 8 | 7.6 | 0 | 0 | 0 | 0 | 0 | |
| 4 | | P. Mahomes | 60 | 10/6/2025 | KC | @ |  JAX | 6 | 10.0 | 1 | 0 | 0 | 0 | 0 | |
| 5 | | P. Mahomes | 60 | 11/24/2024 | KC | @ |  CAR | 5 | 12.0 | 0 | 0 | 0 | 0 | 0 | |
| 6 | | P. Mahomes | 59 | 11/18/2019 | KC | @ |  LAC | 5 | 11.8 | 0 | 0 | 0 | 0 | 0 | |
| 7 | | P. Mahomes | 57 | 9/5/2025 | KC | @ | LAC | 6 | 9.5 | 1 | 0 | 0 | 0 | 0 | |
| 8 | | P. Mahomes | 54 | 1/8/2022 | KC | @ |  DEN | 9 | 6.0 | 0 | 0 | 0 | 0 | 0 | |
| 9 | | P. Mahomes | 54 | 9/20/2020 | KC | @ | LAC | 6 | 9.0 | 0 | 0 | 0 | 0 | 0 | |
| 10 | | P. Mahomes | 54 | 9/29/2019 | KC | @ |  DET | 6 | 9.0 | 0 | 0 | 0 | 0 | 0 | |
| 11 | | P. Mahomes | 53 | 12/25/2023 | KC | vs |  LV | 10 | 5.3 | 0 | 0 | 0 | 0 | 0 | |
| 12 | | P. Mahomes | 52 | 12/2/2018 | KC | @ | OAK | 9 | 5.8 | 0 | 0 | 0 | 0 | 0 | |
| 13 | | P. Mahomes | 51 | 10/1/2023 | KC | @ |  NYJ | 7 | 7.3 | 0 | 0 | 0 | 0 | 0 | |
| 14 | | P. Mahomes | 45 | 9/7/2023 | KC | vs | DET | 6 | 7.5 | 0 | 0 | 0 | 0 | 0 | |
| 15 | | P. Mahomes | 45 | 9/26/2021 | KC | vs | LAC | 4 | 11.3 | 0 | 0 | 0 | 0 | 0 | |
| 16 | | P. Mahomes | 45 | 10/21/2018 | KC | vs |  CIN | 4 | 11.3 | 0 | 0 | 0 | 0 | 0 | |
| 17 | | P. Mahomes | 39 | 10/20/2024 | KC | @ |  SF | 5 | 7.8 | 1 | 0 | 0 | 0 | 0 | |
| 18 | | P. Mahomes | 39 | 11/13/2022 | KC | vs | JAX | 7 | 5.6 | 0 | 0 | 0 | 0 | 0 | |
| 19 | | P. Mahomes | 38 | 11/20/2023 | KC | vs | PHI | 6 | 6.3 | 0 | 0 | 0 | 0 | 0 | |
| 20 | | P. Mahomes | 37 | 12/20/2020 | KC | @ |  NO | 7 | 5.3 | 0 | 0 | 0 | 0 | 0 | |
| 21 | | P. Mahomes | 36 | 11/27/2022 | KC | vs |  LAR | 4 | 9.0 | 0 | 0 | 0 | 0 | 0 | |
| 22 | | P. Mahomes | 36 | 10/19/2020 | KC | @ | BUF | 10 | 3.6 | 0 | 0 | 0 | 0 | 0 | |
| 23 | | P. Mahomes | 35 | 10/24/2021 | KC | @ | TEN | 6 | 5.8 | 0 | 0 | 0 | 0 | 0 | |
| 24 | | P. Mahomes | 34 | 10/2/2022 | KC | @ |  TB | 4 | 8.5 | 0 | 0 | 0 | 0 | 0 | |
| 25 | | P. Mahomes | 33 | 12/21/2024 | KC | vs |  HOU | 5 | 6.6 | 1 | 0 | 0 | 0 | 0 | |
Results may be incomplete. StatMuse has complete game-level data for rushing yards going back to the 1960 season.
More Chiefs Stats
Team Rankings
PPG
26.8
7th
OPP PPG
16.4
2nd
RUSH YDS/G
126.5
9th
PASS YDS/G
262.4
5th
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