The New England Patriots have an 80-52-1 record in the regular season and playoffs against the Bills all-time.
| TEAM | DATE | REC | TM | OPP | RESULT | W% | TD | 1DWN | OFF | OPP OFF | 3DWN% | 4DWN% | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | Patriots | 9/23/1960 | 0-1 | vs | L 0-13 | .000 | 0 | 18 | 284 | 233 | ||||
| 2 | | Patriots | 12/4/1960 | 0-1 | @ | L 14-38 | .000 | 2 | 13 | 167 | 271 | ||||
| 3 | | Patriots | 9/23/1961 | 1-0 | @ | W 23-21 | 1.000 | 2 | 15 | 329 | 175 | ||||
| 4 | | Patriots | 10/22/1961 | 1-0 | vs | W 52-21 | 1.000 | 7 | 18 | 437 | 275 | ||||
| 5 | | Patriots | 11/3/1962 | 0-0-1 | @ | T 28-28 | .500 | 4 | 18 | 375 | 240 | ||||
| 6 | | Patriots | 11/23/1962 | 1-0 | vs | W 21-10 | 1.000 | 3 | 15 | 319 | 255 | ||||
| 7 | | Patriots | 10/26/1963 | 0-1 | @ | L 21-28 | .000 | 3 | 15 | 305 | 350 | ||||
| 8 | | Patriots | 12/1/1963 | 1-0 | vs | W 17-7 | 1.000 | 2 | 10 | 250 | 239 | ||||
| 9 | | Patriots | 12/28/1963 | 1-0 | @ | W 26-8 | 1.000 | 2 | 16 | 375 | 286 | ||||
| 10 | | Patriots | 11/15/1964 | 1-0 | @ | W 36-28 | 1.000 | 5 | 14 | 254 | 386 | ||||
| 11 | | Patriots | 12/20/1964 | 0-1 | vs | L 14-24 | .000 | 2 | 15 | 319 | 380 | ||||
| 12 | | Patriots | 9/11/1965 | 0-1 | @ | L 7-24 | .000 | 1 | 13 | 215 | 348 | ||||
| 13 | | Patriots | 11/7/1965 | 0-1 | vs | L 7-23 | .000 | 1 | 15 | 264 | 161 | ||||
| 14 | | Patriots | 10/8/1966 | 1-0 | @ | W 20-10 | 1.000 | 2 | 12 | 286 | 321 | ||||
| 15 | | Patriots | 12/4/1966 | 1-0 | vs | W 14-3 | 1.000 | 2 | 12 | 226 | 314 | ||||
| 16 | | Patriots | 9/24/1967 | 1-0 | @ | W 23-0 | 1.000 | 2 | 13 | 265 | 241 | ||||
| 17 | | Patriots | 12/9/1967 | 0-1 | vs | L 16-44 | .000 | 2 | 9 | 150 | 252 | ||||
| 18 | | Patriots | 9/8/1968 | 1-0 | @ | W 16-7 | 1.000 | 1 | 9 | 195 | 191 | ||||
| 19 | | Patriots | 10/20/1968 | 1-0 | vs | W 23-6 | 1.000 | 2 | 11 | 299 | 203 | ||||
| 20 | | Patriots | 10/11/1969 | 0-1 | @ | L 16-23 | .000 | 2 | 14 | 248 | 364 | ||||
| 21 | | Patriots | 11/23/1969 | 1-0 | vs | W 35-21 | 1.000 | 5 | 16 | 373 | 425 | ||||
| 22 | | Patriots | 11/1/1970 | 0-1 | vs | L 10-45 | .000 | 1 | 19 | 251 | 364 | ||||
| 23 | | Patriots | 11/29/1970 | 1-0 | @ | W 14-10 | 1.000 | 2 | 10 | 167 | 325 | ||||
| 24 | | Patriots | 11/14/1971 | 1-0 | vs | W 38-33 | 1.000 | 5 | 9 | 299 | 217 | ||||
| 25 | | Patriots | 11/28/1971 | 0-1 | @ | L 20-27 | .000 | 2 | 15 | 294 | 264 | ||||
| Average | .605 | 2.6 | 18.6 | 321.8 | 312.9 | ||||||||||
| Total | 80-52-1 | .605 | 346 | 2,475 | 42,798 | 41,614 | |||||||||
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More Patriots Stats
Team Leaders 
PASS
386
Maye
RUSH
94
Stevenson
REC
96
Doubs
Team Rankings
PPG
15.0
26th
OPP PPG
8.0
1st
RUSH YDS/G
122.5
10th
PASS YDS/G
193.0
25th
Jets
Dolphins
JAX
LV
CHI
NFL 2026 Leaders
NFL 2026 Rankings
NFL Fantasy 2026
NFL 2026 Betting
NFL 2026 Standings
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
2 | 0 | 0 | 1.000 | |
1 | 1 | 0 | .500 | |
1 | 1 | 0 | .500 | |
0 | 2 | 0 | .000 | |
| NFC North | W | L | T | PCT |
2 | 0 | 0 | 1.000 | |
1 | 1 | 0 | .500 | |
1 | 1 | 0 | .500 | |
1 | 1 | 0 | .500 | |
| NFC South | W | L | T | PCT |
1 | 1 | 0 | .500 | |
1 | 1 | 0 | .500 | |
0 | 2 | 0 | .000 | |
0 | 2 | 0 | .000 | |
| NFC West | W | L | T | PCT |
2 | 0 | 0 | 1.000 | |
2 | 0 | 0 | 1.000 | |
1 | 1 | 0 | .500 | |
1 | 1 | 0 | .500 |
Eagles
Giants
Cowboys
Commanders
Vikings
Lions
Packers
Panthers
Saints
Buccaneers
Falcons
Seahawks
49ers
Rams
Cardinals| AFC East | W | L | T | PCT |
|---|---|---|---|---|
2 | 0 | 0 | 1.000 | |
1 | 1 | 0 | .500 | |
1 | 1 | 0 | .500 | |
0 | 2 | 0 | .000 | |
| AFC North | W | L | T | PCT |
2 | 0 | 0 | 1.000 | |
1 | 1 | 0 | .500 | |
1 | 1 | 0 | .500 | |
1 | 1 | 0 | .500 | |
| AFC South | W | L | T | PCT |
1 | 1 | 0 | .500 | |
0 | 2 | 0 | .000 | |
0 | 2 | 0 | .000 | |
0 | 2 | 0 | .000 | |
| AFC West | W | L | T | PCT |
2 | 0 | 0 | 1.000 | |
2 | 0 | 0 | 1.000 | |
1 | 1 | 0 | .500 | |
0 | 2 | 0 | .000 |
Bengals
Ravens
Steelers
Browns
Titans
Texans
Colts
Chiefs
Broncos
Chargers