Reggie Bush had his fewest rushing yards in a game on December 24, 2016 and on October 30, 2016, with -8 yards.

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reggie bush least rushing uards
Interpreted as:
Reggie Bush least rushing in a regular-season game uards
12/24/2016Bush10/30/2016Bush11/5/2006Bush9/11/2016Bush12/19/2010Bush10/11/2015Bush1/1/2017Bush11/27/2016Bush11/20/2016Bush11/7/2016Bush9/15/2016Bush11/1/2015Bush10/4/2015Bush12/27/2010Bush12/6/2009Bush11/30/2008Bush10/23/2016Bush11/25/2010Bush12/4/2016Bush10/9/2016Bush11/2/2009Bush12/11/2016Bush9/20/2010Bush-8-8-5-4-4-100000000001133344
Results may be incomplete. StatMuse has complete game-level data for rushing yards going back to the 1960 season.