Ryan Fitzpatrick had his most rushing yards in a game versus the Jets on October 3, 2010, with 74 yards.
Interpreted as:
Ryan Fitzpatrick most rushing yds in a regular-season game| NAME | RUSH YDS | DATE | TM | OPP | ATT | YPC | RUSH TD | REC YDS | REC | TRG | AVG | REC TD | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | R. Fitzpatrick | 74 | 10/3/2010 | vs | 7 | 10.6 | 0 | 0 | 0 | 0 | 0 | |||
| 2 |  | R. Fitzpatrick | 65 | 12/8/2019 | @ | 7 | 9.3 | 0 | 0 | 0 | 0 | 0 | |||
| 3 |  | R. Fitzpatrick | 54 | 12/1/2013 | @ | 8 | 6.8 | 1 | 0 | 0 | 0 | 0 | |||
| 4 |  | R. Fitzpatrick | 52 | 11/2/2008 | vs | 3 | 17.3 | 0 | 0 | 0 | 0 | 0 | |||
| 5 | | R. Fitzpatrick | 50 | 10/6/2013 | vs | 6 | 8.3 | 1 | 0 | 1 | 1 | 0.0 | 0 | ||
| 6 | | R. Fitzpatrick | 50 | 11/29/2009 | vs | 7 | 7.1 | 1 | 0 | 0 | 0 | 0 | |||
| 7 |  | R. Fitzpatrick | 49 | 11/2/2014 | vs | 6 | 8.2 | 0 | 0 | 0 | 0 | 0 | |||
| 8 | | R. Fitzpatrick | 49 | 12/12/2010 | vs | 4 | 12.3 | 0 | 0 | 0 | 0 | 0 | |||
| 9 | | R. Fitzpatrick | 47 | 10/4/2020 | vs | 6 | 7.8 | 1 | 0 | 0 | 0 | 0 | |||
| 10 | | R. Fitzpatrick | 45 | 11/24/2019 | @ | 5 | 9.0 | 1 | 0 | 0 | 0 | 0 | |||
| 11 | | R. Fitzpatrick | 43 | 10/31/2010 | @ | 6 | 7.2 | 0 | 0 | 0 | 0 | 0 | |||
| 12 | | R. Fitzpatrick | 42 | 10/26/2008 | @ | 7 | 6.0 | 0 | 0 | 0 | 0 | 0 | |||
| 13 | | R. Fitzpatrick | 41 | 9/28/2008 | vs | 4 | 10.3 | 0 | 0 | 0 | 0 | 0 | |||
| 14 | | R. Fitzpatrick | 38 | 9/24/2020 | @ | 7 | 5.4 | 1 | 0 | 1 | 1 | 0.0 | 0 | ||
| 15 |  | R. Fitzpatrick | 36 | 9/9/2018 | @ | 12 | 3.0 | 1 | 0 | 0 | 0 | 0 | |||
| 16 | | R. Fitzpatrick | 36 | 1/1/2012 | @ | 5 | 7.2 | 0 | 0 | 0 | 0 | 0 | |||
| 17 | | R. Fitzpatrick | 35 | 11/11/2018 | vs | 8 | 4.4 | 0 | 0 | 0 | 0 | 0 | |||
| 18 |  | R. Fitzpatrick | 34 | 10/4/2015 | @ | 9 | 3.8 | 0 | 0 | 0 | 0 | 0 | |||
| 19 | | R. Fitzpatrick | 34 | 9/21/2014 | @ | 7 | 4.9 | 1 | 0 | 0 | 0 | 0 | |||
| 20 | | R. Fitzpatrick | 34 | 9/16/2012 | vs | 4 | 8.5 | 0 | 0 | 0 | 0 | 0 | |||
| 21 | | R. Fitzpatrick | 34 | 11/27/2011 | @ | 5 | 6.8 | 0 | 0 | 0 | 0 | 0 | |||
| 22 | | R. Fitzpatrick | 33 | 12/15/2019 | @ | 4 | 8.3 | 0 | 0 | 0 | 0 | 0 | |||
| 23 | | R. Fitzpatrick | 33 | 10/13/2013 | @ | 6 | 5.5 | 0 | 0 | 0 | 0 | 0 | |||
| 24 | | R. Fitzpatrick | 32 | 12/3/2009 | vs | 5 | 6.4 | 0 | 0 | 0 | 0 | 0 | |||
| 25 | | R. Fitzpatrick | 31 | 10/18/2015 | vs | 4 | 7.8 | 1 | 0 | 0 | 0 | 0 | |||
NYJ
NYJ
WASResults may be incomplete. StatMuse has complete game-level data for rushing yards going back to the 1960 season.
More Bills Stats
Team Leaders 
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3,668
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Team Rankings
PPG
28.3
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OPP PPG
21.5
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RUSH YDS/G
159.6
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PASS YDS/G
234.2
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NFL 2025 Rankings
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NFL 2025 Standings
| AFC East | W | L | T | PCT |
|---|---|---|---|---|
 Patriots - y | 14 | 3 | 0 | .824 |
 Bills - w | 12 | 5 | 0 | .706 |
 Dolphins - e | 7 | 10 | 0 | .412 |
 Jets - e | 3 | 14 | 0 | .176 |
| AFC North | W | L | T | PCT |
 Steelers - y | 10 | 7 | 0 | .588 |
 Ravens - e | 8 | 9 | 0 | .471 |
 Bengals - e | 6 | 11 | 0 | .353 |
 Browns - e | 5 | 12 | 0 | .294 |
| AFC South | W | L | T | PCT |
 Jaguars - y | 13 | 4 | 0 | .765 |
 Texans - w | 12 | 5 | 0 | .706 |
 Colts - e | 8 | 9 | 0 | .471 |
 Titans - e | 3 | 14 | 0 | .176 |
| AFC West | W | L | T | PCT |
 Broncos - z* | 14 | 3 | 0 | .824 |
 Chargers - w | 11 | 6 | 0 | .647 |
 Chiefs - e | 6 | 11 | 0 | .353 |
 Raiders - e | 3 | 14 | 0 | .176 |
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
 Eagles - y | 11 | 6 | 0 | .647 |
 Cowboys - e | 7 | 9 | 1 | .441 |
 Commanders - e | 5 | 12 | 0 | .294 |
 Giants - e | 4 | 13 | 0 | .235 |
| NFC North | W | L | T | PCT |
 Bears - y | 11 | 6 | 0 | .647 |
 Packers - w | 9 | 7 | 1 | .559 |
 Vikings - e | 9 | 8 | 0 | .529 |
 Lions - e | 9 | 8 | 0 | .529 |
| NFC South | W | L | T | PCT |
 Panthers - y | 8 | 9 | 0 | .471 |
 Buccaneers - e | 8 | 9 | 0 | .471 |
 Falcons - e | 8 | 9 | 0 | .471 |
 Saints - e | 6 | 11 | 0 | .353 |
| NFC West | W | L | T | PCT |
 Seahawks - z* | 14 | 3 | 0 | .824 |
 Rams - w | 12 | 5 | 0 | .706 |
 49ers - w | 12 | 5 | 0 | .706 |
 Cardinals - e | 3 | 14 | 0 | .176 |
