Running backs rushed for their most yards in a game in a 21 to 13 win by the Rams against the Baltimore Colts on November 22, 1953, with 550 yards.
Interpreted as:
single regular-season game record rb rushing yards| POSITION | RUSH YDS | DATE | TM | OPP | ATT | YPC | RUSH TD | REC YDS | REC | TRG | AVG | REC TD | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Running Back | 550 | 11/22/1953 | @ | 77 | 7.1 | 3 | |||||||
| 2 | Running Back | 524 | 11/15/1959 | vs | 64 | 8.2 | 5 | |||||||
| 3 | Running Back | 501 | 10/8/1950 | @ | 77 | 6.5 | 5 | |||||||
| 4 | Running Back | 496 | 11/6/1955 | vs | 70 | 7.1 | 7 | |||||||
| 5 | Running Back | 488 | 12/6/1981 | @ | 83 | 5.9 | 5 | 31 | 6 | 5.2 | 1 | |||
| 6 | Running Back | 486 | 11/24/1957 | @ | 83 | 5.9 | 7 | |||||||
| 7 | Running Back | 482 | 12/24/2016 | @ | 72 | 6.7 | 3 | 34 | 8 | 9 | 4.3 | 0 | ||
| 8 | Running Back | 479 | 10/7/1973 | vs | 76 | 6.3 | 1 | 87 | 10 | 8.7 | 1 | |||
| 9 | Running Back | 475 | 11/25/1973 | @ | 78 | 6.1 | 1 | 87 | 11 | 7.9 | 1 | |||
| 10 | Running Back | 468 | 11/26/1978 | @ | 79 | 5.9 | 5 | 81 | 9 | 9.0 | 1 | |||
| 11 | Running Back | 463 | 11/1/2009 | vs | 49 | 9.4 | 4 | 8 | 4 | 8 | 2.0 | 0 | ||
| 12 | Running Back | 462 | 12/20/2009 | vs | 69 | 6.7 | 4 | 28 | 4 | 7 | 7.0 | 0 | ||
| 13 | Running Back | 461 | 12/28/2008 | vs | 64 | 7.2 | 5 | 85 | 7 | 11 | 12.1 | 0 | ||
| 14 | Running Back | 457 | 11/23/1950 | @ | 57 | 8.0 | 3 | |||||||
| 15 | Running Back | 455 | 11/25/1976 | @ | 77 | 5.9 | 3 | 7 | 1 | 7.0 | 0 | |||
| 16 | Running Back | 452 | 12/17/1978 | vs | 76 | 5.9 | 4 | 91 | 8 | 11.4 | 0 | |||
| 17 | Running Back | 451 | 10/30/1977 | vs | 74 | 6.1 | 3 | 25 | 4 | 6.3 | 0 | |||
| 18 | Running Back | 450 | 10/7/1979 | @ | 67 | 6.7 | 4 | 120 | 10 | 12.0 | 2 | |||
| 19 | Running Back | 449 | 9/10/1978 | @ | 78 | 5.8 | 4 | 64 | 11 | 5.8 | 0 | |||
| 20 | Running Back | 449 | 9/16/1973 | @ | 70 | 6.4 | 6 | 151 | 8 | 18.9 | 0 | |||
| 21 | Running Back | 448 | 11/1/1959 | @ | 64 | 7.0 | 4 | |||||||
| 22 | Running Back | 448 | 12/2/1951 | @ | 79 | 5.7 | 6 | |||||||
| 23 | Running Back | 447 | 11/23/1972 | vs | 67 | 6.7 | 2 | 57 | 3 | 19.0 | 0 | |||
| 24 | Running Back | 447 | 12/18/1966 | vs | 76 | 5.9 | 2 | 137 | 7 | 19.6 | 1 | |||
| 25 | Running Back | 444 | 10/30/1977 | @ | 71 | 6.3 | 2 | 139 | 8 | 17.4 | 1 | |||
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HOUResults may be incomplete. StatMuse has complete game-level data for rushing yards going back to the 1960 season.
More Colts Stats
Team Leaders 
PASS
3,101
Jones
RUSH
1,585
Taylor
REC
1,003
Pierce
Team Rankings
PPG
27.4
8th
OPP PPG
24.2
21st
RUSH YDS/G
118.1
17th
PASS YDS/G
240.3
8th
NFL 2025 Leaders
NFL 2025 Rankings
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NFL 2025 Standings
| AFC East | W | L | T | PCT |
|---|---|---|---|---|
 Patriots - y | 14 | 3 | 0 | .824 |
 Bills - w | 12 | 5 | 0 | .706 |
 Dolphins - e | 7 | 10 | 0 | .412 |
 Jets - e | 3 | 14 | 0 | .176 |
| AFC North | W | L | T | PCT |
 Steelers - y | 10 | 7 | 0 | .588 |
 Ravens - e | 8 | 9 | 0 | .471 |
 Bengals - e | 6 | 11 | 0 | .353 |
 Browns - e | 5 | 12 | 0 | .294 |
| AFC South | W | L | T | PCT |
 Jaguars - y | 13 | 4 | 0 | .765 |
 Texans - w | 12 | 5 | 0 | .706 |
 Colts - e | 8 | 9 | 0 | .471 |
 Titans - e | 3 | 14 | 0 | .176 |
| AFC West | W | L | T | PCT |
 Broncos - z* | 14 | 3 | 0 | .824 |
 Chargers - w | 11 | 6 | 0 | .647 |
 Chiefs - e | 6 | 11 | 0 | .353 |
 Raiders - e | 3 | 14 | 0 | .176 |
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
 Eagles - y | 11 | 6 | 0 | .647 |
 Cowboys - e | 7 | 9 | 1 | .441 |
 Commanders - e | 5 | 12 | 0 | .294 |
 Giants - e | 4 | 13 | 0 | .235 |
| NFC North | W | L | T | PCT |
 Bears - y | 11 | 6 | 0 | .647 |
 Packers - w | 9 | 7 | 1 | .559 |
 Vikings - e | 9 | 8 | 0 | .529 |
 Lions - e | 9 | 8 | 0 | .529 |
| NFC South | W | L | T | PCT |
 Panthers - y | 8 | 9 | 0 | .471 |
 Buccaneers - e | 8 | 9 | 0 | .471 |
 Falcons - e | 8 | 9 | 0 | .471 |
 Saints - e | 6 | 11 | 0 | .353 |
| NFC West | W | L | T | PCT |
 Seahawks - z* | 14 | 3 | 0 | .824 |
 Rams - w | 12 | 5 | 0 | .706 |
 49ers - w | 12 | 5 | 0 | .706 |
 Cardinals - e | 3 | 14 | 0 | .176 |
