The Arizona Cardinals had the lowest spread by a team in a game in 2021, at -20 points versus the Texans on October 24, 2021.
| TEAM | DATE | TM | OPP | RESULT | SPREAD | ATS DIFF | O/U | O/U DIFF | TD | 1DWN | OFF | OPP OFF | 3DWN% | 4DWN% | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | Cardinals | 10/24/2021 | -2298 | vs | +1086 | W 31-5 | -20 | +6 (Y) | 47.5 | -11.5 (U) | 4 | 24 | 397 | 160 | 50.0 | 100.0 | ||
| 2 |  | Bills | 10/3/2021 | -1784 | vs | +957 | W 40-0 | -19 | +21 (Y) | 47.5 | -7.5 (U) | 4 | 26 | 450 | 109 | 41.7 | 50.0 | ||
| 3 |  | Patriots | 1/2/2022 | -1308 | vs | +775 | W 50-10 | -17 | +23 (Y) | 41.5 | +18.5 (O) | 7 | 32 | 471 | 253 | 80.0 | |||
| 4 |  | Rams | 10/31/2021 | -1269 | @ | +764 | W 38-22 | -16.5 | -0.5 (N) | 47 | +13 (O) | 5 | 26 | 467 | 323 | 36.4 | 0.0 | ||
| 5 | | Rams | 10/24/2021 | -1367 | vs | +807 | W 28-19 | -16.5 | -7.5 (N) | 50.5 | -3.5 (U) | 3 | 22 | 374 | 415 | 69.2 | 0.0 | ||
| 6 | | Bills | 1/9/2022 | -1163 | vs | +714 | W 27-10 | -16 | +1 (Y) | 43 | -6 (U) | 3 | 25 | 424 | 63 | 44.4 | 0.0 | ||
| 7 | | Bills | 10/31/2021 | -1046 | vs | +681 | W 26-11 | -15 | 0 (P) | 48.5 | -11.5 (U) | 3 | 24 | 351 | 262 | 46.2 | 0.0 | ||
| 8 |  | Buccaneers | 1/2/2022 | -858 | @ | +586 | W 28-24 | -14.5 | -10.5 (N) | 47.5 | +4.5 (O) | 3 | 26 | 467 | 374 | 60.0 | 100.0 | ||
| 9 | | Bills | 12/19/2021 | -834 | vs | +557 | W 31-14 | -14.5 | +2.5 (Y) | 43 | +2 (O) | 4 | 21 | 312 | 275 | 42.9 | 100.0 | ||
| 10 | | Bills | 11/7/2021 | -1144 | @ | +704 | L 6-9 | -14.5 | -17.5 (N) | 48.5 | -33.5 (U) | 0 | 17 | 301 | 218 | 40.0 | 0.0 | ||
| 11 |  | Colts | 1/9/2022 | -995 | @ | +636 | L 11-26 | -14 | -29 (N) | 43 | -6 (U) | 1 | 13 | 233 | 318 | 33.3 | 40.0 | ||
| 12 | | Bills | 1/2/2022 | -947 | vs | +625 | W 29-15 | -14 | 0 (P) | 46 | -2 (U) | 4 | 28 | 351 | 265 | 58.3 | 100.0 | ||
| 13 | | Rams | 12/5/2021 | -811 | vs | +553 | W 37-7 | -14 | +16 (Y) | 48 | -4 (U) | 4 | 24 | 418 | 197 | 41.7 | 100.0 | ||
| 14 |  | 49ers | 1/2/2022 | -740 | vs | +507 | W 23-7 | -13.5 | +2.5 (Y) | 44.5 | -14.5 (U) | 2 | 19 | 416 | 222 | 38.5 | 0.0 | ||
| 15 |  | Browns | 11/21/2021 | -658 | vs | +469 | W 13-10 | -13.5 | -10.5 (N) | 42.5 | -19.5 (U) | 2 | 22 | 349 | 245 | 38.5 | |||
| 16 | | Bills | 11/14/2021 | -777 | @ | +533 | W 45-17 | -13.5 | +14.5 (Y) | 48.5 | +13.5 (O) | 6 | 26 | 489 | 366 | 57.1 | |||
| 17 | | Browns | 9/19/2021 | -739 | vs | +516 | W 31-21 | -13.5 | -3.5 (N) | 48.5 | +3.5 (O) | 4 | 22 | 355 | 302 | 44.4 | |||
| 18 |  | Chargers | 12/26/2021 | -670 | @ | +470 | L 29-41 | -13 | -25 (N) | 45.5 | +24.5 (O) | 3 | 25 | 417 | 437 | 66.7 | |||
| 19 | | Cardinals | 12/19/2021 | -710 | @ | +497 | L 12-30 | -13 | -31 (N) | 48 | -6 (U) | 1 | 23 | 394 | 338 | 46.7 | 33.3 | ||
| 20 |  | Packers | 1/2/2022 | -735 | vs | +509 | W 37-10 | -12.5 | +14.5 (Y) | 42.5 | +4.5 (O) | 4 | 29 | 481 | 206 | 53.8 | 0.0 | ||
| 21 |  | Broncos | 12/12/2021 | -645 | vs | +455 | W 38-10 | -12.5 | +15.5 (Y) | 42 | +6 (O) | 5 | 25 | 358 | 316 | 66.7 | 100.0 | ||
| 22 | | Buccaneers | 9/19/2021 | -771 | vs | +540 | W 48-25 | -12.5 | +10.5 (Y) | 52 | +21 (O) | 7 | 21 | 341 | 348 | 33.3 | 50.0 | ||
| 23 |  | Chiefs | 1/16/2022 | -663 | vs | +463 | W 42-21 | -12 | +9 (Y) | 46.5 | +16.5 (O) | 6 | 26 | 478 | 257 | 66.7 | |||
| 24 | | Buccaneers | 10/24/2021 | -689 | vs | +492 | W 38-3 | -12 | +23 (Y) | 47 | -6 (U) | 5 | 28 | 408 | 311 | 33.3 | 50.0 | ||
| 25 | | Chiefs | 1/8/2022 | -603 | @ | +437 | W 28-24 | -11.5 | -7.5 (N) | 44.5 | +7.5 (O) | 3 | 28 | 390 | 364 | 57.1 | 100.0 | ||
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More Cardinals Stats
Team Leaders 
PASS
3,366
Brissett
RUSH
333
Carter
REC
1,239
McBride
Team Rankings
PPG
20.9
23rd
OPP PPG
28.7
29th
RUSH YDS/G
93.1
31st
PASS YDS/G
256.1
5th
NFL 2025 Leaders
NFL 2025 Rankings
NFL Fantasy 2025
NFL 2025 Betting
NFL 2025 Standings
| AFC East | W | L | T | PCT |
|---|---|---|---|---|
 Patriots - y | 14 | 3 | 0 | .824 |
 Bills - w | 12 | 5 | 0 | .706 |
 Dolphins - e | 7 | 10 | 0 | .412 |
 Jets - e | 3 | 14 | 0 | .176 |
| AFC North | W | L | T | PCT |
 Steelers - y | 10 | 7 | 0 | .588 |
 Ravens - e | 8 | 9 | 0 | .471 |
 Bengals - e | 6 | 11 | 0 | .353 |
 Browns - e | 5 | 12 | 0 | .294 |
| AFC South | W | L | T | PCT |
 Jaguars - y | 13 | 4 | 0 | .765 |
 Texans - w | 12 | 5 | 0 | .706 |
 Colts - e | 8 | 9 | 0 | .471 |
 Titans - e | 3 | 14 | 0 | .176 |
| AFC West | W | L | T | PCT |
 Broncos - z* | 14 | 3 | 0 | .824 |
 Chargers - w | 11 | 6 | 0 | .647 |
 Chiefs - e | 6 | 11 | 0 | .353 |
 Raiders - e | 3 | 14 | 0 | .176 |
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
 Eagles - y | 11 | 6 | 0 | .647 |
 Cowboys - e | 7 | 9 | 1 | .441 |
 Commanders - e | 5 | 12 | 0 | .294 |
 Giants - e | 4 | 13 | 0 | .235 |
| NFC North | W | L | T | PCT |
 Bears - y | 11 | 6 | 0 | .647 |
 Packers - w | 9 | 7 | 1 | .559 |
 Vikings - e | 9 | 8 | 0 | .529 |
 Lions - e | 9 | 8 | 0 | .529 |
| NFC South | W | L | T | PCT |
 Panthers - y | 8 | 9 | 0 | .471 |
 Buccaneers - e | 8 | 9 | 0 | .471 |
 Falcons - e | 8 | 9 | 0 | .471 |
 Saints - e | 6 | 11 | 0 | .353 |
| NFC West | W | L | T | PCT |
 Seahawks - z* | 14 | 3 | 0 | .824 |
 Rams - w | 12 | 5 | 0 | .706 |
 49ers - w | 12 | 5 | 0 | .706 |
 Cardinals - e | 3 | 14 | 0 | .176 |