Matt Flynn has the most passing touchdowns by a quarterback in a home, Week-17 game, with 6 touchdowns versus the Lions on January 1, 2012.
| NAME | TD | DATE | TM | OPP | CMP | ATT | PCT | YDS | AVG | INT | RTG | TD% | INT% | SCK | SCKY | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | M. Flynn | 6 | 1/1/2012 |  GB | vs |  DET | 31 | 44 | 70.5 | 480 | 10.9 | 1 | 136.4 | 13.6 | 2.3 | 3 | 11 |
| 2 |  | B. Mayfield | 5 | 12/29/2024 |  TB | vs |  CAR | 27 | 32 | 84.4 | 359 | 11.2 | 0 | 153.0 | 15.6 | 0.0 | 2 | 10 |
| 3 |  | L. Jackson | 5 | 12/31/2023 |  BAL | vs |  MIA | 18 | 21 | 85.7 | 321 | 15.3 | 0 | 158.3 | 23.8 | 0.0 | 1 | 9 |
| 4 |  | E. Manning | 5 | 12/30/2012 |  NYG | vs |  PHI | 13 | 21 | 61.9 | 208 | 9.9 | 0 | 134.5 | 23.8 | 0.0 | 1 | 11 |
| 5 |  | D. Brees | 5 | 1/1/2012 |  NO | vs | CAR | 28 | 35 | 80.0 | 389 | 11.1 | 1 | 140.7 | 14.3 | 2.9 | 0 | 0 |
| 6 | | R. Gannon | 5 | 12/24/2000 |  OAK | vs | CAR | 26 | 32 | 81.3 | 230 | 7.2 | 0 | 136.2 | 15.6 | 0.0 | 0 | 0 |
| 7 | | S. Beuerlein | 5 | 1/2/2000 | CAR | vs | NO | 22 | 41 | 53.7 | 322 | 7.9 | 0 | 119.1 | 12.2 | 0.0 | 6 | 34 |
| 8 |  | D. Lock | 4 | 12/29/2024 | NYG | vs |  IND | 17 | 23 | 73.9 | 309 | 13.4 | 0 | 155.3 | 17.4 | 0.0 | 0 | 0 |
| 9 |  | J. Burrow | 4 | 1/2/2022 |  CIN | vs |  KC | 30 | 39 | 76.9 | 446 | 11.4 | 0 | 148.0 | 10.3 | 0.0 | 4 | 31 |
| 10 |  | R. Wilson | 4 | 1/2/2022 |  SEA | vs | DET | 20 | 29 | 69.0 | 236 | 8.1 | 0 | 133.0 | 13.8 | 0.0 | 1 | 4 |
| 11 |  | T. Brady | 4 | 1/3/2021 | TB | vs |  ATL | 26 | 41 | 63.4 | 399 | 9.7 | 1 | 117.8 | 9.8 | 2.4 | 1 | 8 |
| 12 |  | D. Prescott | 4 | 12/29/2019 |  DAL | vs |  WAS | 23 | 33 | 69.7 | 303 | 9.2 | 0 | 138.0 | 12.1 | 0.0 | 3 | 9 |
| 13 |  | T. Brady | 4 | 12/30/2018 |  NE | vs |  NYJ | 24 | 33 | 72.7 | 250 | 7.6 | 0 | 133.8 | 12.1 | 0.0 | 1 | 6 |
| 14 |  | J. Winston | 4 | 12/30/2018 | TB | vs | ATL | 22 | 35 | 62.9 | 345 | 9.9 | 1 | 121.7 | 11.4 | 2.9 | 1 | 4 |
| 15 |  | J. Goff | 4 | 12/30/2018 |  LAR | vs |  SF | 15 | 26 | 57.7 | 199 | 7.7 | 0 | 121.6 | 15.4 | 0.0 | 0 | 0 |
| 16 |  | M. Ryan | 4 | 1/1/2017 | ATL | vs | NO | 27 | 36 | 75.0 | 331 | 9.2 | 0 | 139.9 | 11.1 | 0.0 | 1 | 8 |
| 17 | | D. Brees | 4 | 12/29/2013 | NO | vs | TB | 24 | 31 | 77.4 | 381 | 12.3 | 0 | 157.4 | 12.9 | 0.0 | 1 | 11 |
| 18 | | D. Brees | 4 | 12/30/2012 | NO | vs | CAR | 29 | 43 | 67.4 | 396 | 9.2 | 1 | 118.0 | 9.3 | 2.3 | 2 | 18 |
| 19 |  | B. Favre | 4 | 1/3/2010 |  MIN | vs | NYG | 25 | 31 | 80.6 | 316 | 10.2 | 0 | 148.7 | 12.9 | 0.0 | 0 | 0 |
| 20 |  | K. Warner | 4 | 12/28/2008 |  ARI | vs | SEA | 19 | 30 | 63.3 | 263 | 8.8 | 1 | 117.1 | 13.3 | 3.3 | 1 | 0 |
| 21 | | D. Brees | 4 | 12/28/2008 | NO | vs | CAR | 30 | 49 | 61.2 | 386 | 7.9 | 1 | 104.6 | 8.2 | 2.0 | 2 | 19 |
| 22 | | C. Redman | 4 | 12/30/2007 | ATL | vs | SEA | 17 | 27 | 63.0 | 251 | 9.3 | 0 | 132.9 | 14.8 | 0.0 | 2 | 11 |
| 23 | | E. Manning | 4 | 12/29/2007 | NYG | vs | NE | 22 | 32 | 68.8 | 251 | 7.8 | 1 | 118.6 | 12.5 | 3.1 | 1 | 14 |
| 24 | | T. Brady | 4 | 12/27/2003 | NE | vs |  BUF | 21 | 32 | 65.6 | 204 | 6.4 | 0 | 122.9 | 12.5 | 0.0 | 2 | 14 |
| 25 | | C. Pennington | 4 | 12/29/2002 | NYJ | vs | GB | 17 | 24 | 70.8 | 196 | 8.2 | 0 | 134.7 | 16.7 | 0.0 | 1 | 2 |
Results may be incomplete. StatMuse has complete game-level data for passing touchdowns going back to the 1950 season.
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