Between the 1970 and 1979 seasons, O.J. Simpson rushed for the most yards by a running back, with 10,539 yards.
| NAME | RUSH YDS | GP | ATT | YPC | RUSH YDS/G | RUSH TD | REC YDS | REC | TRG | AVG | REC YDS/G | REC TD | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | O.J. Simpson | 10,539 | 122 | 2,223 | 4.7 | 86.4 | 59 | 1,799 | 173 | 10.4 | 14.7 | 11 | |
| 2 |  | F. Harris | 8,563 | 111 | 2,012 | 4.3 | 77.1 | 72 | 1,311 | 174 | 7.5 | 11.8 | 4 | |
| 3 | | L. Csonka | 6,975 | 124 | 1,622 | 4.3 | 56.3 | 56 | 519 | 74 | 7.0 | 4.2 | 2 | |
| 4 |  | W. Payton | 6,926 | 73 | 1,548 | 4.5 | 94.9 | 59 | 1,424 | 156 | 9.1 | 19.5 | 4 | |
| 5 | | J. Riggins | 6,822 | 111 | 1,666 | 4.1 | 61.5 | 42 | 1,891 | 216 | 8.8 | 17.0 | 12 | |
| 6 | | L. Mitchell | 6,518 | 109 | 1,668 | 3.9 | 59.8 | 30 | 3,182 | 374 | 8.5 | 29.2 | 17 | |
| 7 | | L. McCutcheon | 6,186 | 89 | 1,435 | 4.3 | 69.5 | 23 | 1,683 | 184 | 9.1 | 18.9 | 12 | |
| 8 | | C. Foreman | 5,887 | 93 | 1,533 | 3.8 | 63.3 | 52 | 3,057 | 336 | 9.1 | 32.9 | 23 | |
| 9 | | G. Pruitt | 5,255 | 87 | 1,087 | 4.8 | 60.4 | 25 | 1,942 | 208 | 9.3 | 22.3 | 8 | |
| 10 | | J. Brockington | 5,185 | 95 | 1,347 | 3.8 | 54.6 | 30 | 1,297 | 157 | 8.3 | 13.7 | 4 | |
| 11 | | S. Cunningham | 5,163 | 90 | 1,290 | 4.0 | 57.4 | 39 | 1,813 | 198 | 9.2 | 20.1 | 6 | |
| 12 | | C. Hill | 5,107 | 114 | 1,243 | 4.1 | 44.8 | 34 | 2,096 | 207 | 10.1 | 18.4 | 15 | |
| 13 | | L. Brown | 4,987 | 88 | 1,328 | 3.8 | 56.7 | 31 | 2,183 | 204 | 10.7 | 24.8 | 20 | |
| 14 | | D. Williams | 4,927 | 84 | 1,125 | 4.4 | 58.7 | 31 | 1,208 | 121 | 10.0 | 14.4 | 6 | |
| 15 | | M. van Eeghen | 4,919 | 88 | 1,214 | 4.1 | 55.9 | 28 | 1,148 | 126 | 9.1 | 13.0 | 3 | |
| 16 | | F. Little | 4,629 | 84 | 1,207 | 3.8 | 55.1 | 33 | 1,858 | 170 | 10.9 | 22.1 | 7 | |
| 17 | | M. Lane | 4,489 | 110 | 1,158 | 3.9 | 40.8 | 29 | 2,725 | 278 | 9.8 | 24.8 | 7 | |
| 18 | | E. Podolak | 4,451 | 100 | 1,157 | 3.8 | 44.5 | 34 | 2,456 | 288 | 8.5 | 24.6 | 6 | |
| 19 | | M. Hubbard | 4,425 | 89 | 930 | 4.8 | 49.7 | 23 | 598 | 83 | 7.2 | 6.7 | 1 | |
| 20 | | J. Otis | 4,350 | 116 | 1,160 | 3.8 | 37.5 | 19 | 549 | 90 | 6.1 | 4.7 | 3 | |
| 21 | | R. Newhouse | 4,187 | 111 | 1,005 | 4.2 | 37.7 | 24 | 860 | 111 | 7.7 | 7.7 | 5 | |
| 22 | | D. Hampton | 4,171 | 79 | 1,068 | 3.9 | 52.8 | 21 | 940 | 104 | 9.0 | 11.9 | 4 | |
| 23 | | M. Morris | 4,023 | 85 | 781 | 5.2 | 47.3 | 30 | 478 | 48 | 10.0 | 5.6 | 1 | |
| 24 | | O. Armstrong | 3,983 | 87 | 917 | 4.3 | 45.8 | 21 | 1,279 | 124 | 10.3 | 14.7 | 7 | |
| 25 | | A. Taylor | 3,949 | 81 | 1,047 | 3.8 | 48.8 | 24 | 1,437 | 160 | 9.0 | 17.7 | 6 | |
StatMuse has season-level data for rushing yards going back to the 1932 season.
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RUSH YDS/G
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