Emmitt Smith had the most games with 50+ rushing yards, with 173 games.

Interpreted as:

Who has the most 50 or more rushing yard regular-season games?

	NAME	GP	RUSH YDS	ATT	YPC	RUSH YDS/G	RUSH TD	REC YDS	REC	TRG	AVG	REC YDS/G	REC TD
1	Emmitt Smith E. Smith	173	16,920	3,832	4.4	97.8	147	2,784	446	95	6.2	16.1	10
2	Frank Gore F. Gore	155	13,473	2,827	4.8	86.9	75	2,840	338	485	8.4	18.3	11
3	Walter Payton W. Payton	148	15,392	3,333	4.6	104.0	100	3,537	384		9.2	23.9	11
4	Curtis Martin C. Martin	135	13,102	3,099	4.2	97.1	83	2,705	386	323	7.0	20.0	10
5	Barry Sanders B. Sanders	128	14,443	2,726	5.3	112.8	93	2,328	276		8.4	18.2	9
6	Adrian Peterson A. Peterson	127	13,467	2,659	5.1	106.0	108	1,916	232	323	8.3	15.1	6
7	Jerome Bettis J. Bettis	127	12,166	2,889	4.2	95.8	69	1,087	146	71	7.4	8.6	3
8	LaDainian Tomlinson L. Tomlinson	125	12,324	2,680	4.6	98.6	132	3,516	451	622	7.8	28.1	15
9	Tony Dorsett T. Dorsett	119	11,025	2,327	4.7	92.6	70	2,657	291		9.1	22.3	11
10	Franco Harris F. Harris	119	10,562	2,353	4.5	88.8	83	1,569	203		7.7	13.2	5
11	Edgerrin James E. James	116	11,451	2,746	4.2	98.7	75	2,972	375	499	7.9	25.6	10
12	Marcus Allen M. Allen	115	9,334	2,102	4.4	81.2	84	3,159	367		8.6	27.5	14
13	Steven Jackson S. Jackson	114	10,038	2,277	4.4	88.1	57	2,908	358	484	8.1	25.5	6
14	Eric Dickerson E. Dickerson	113	12,352	2,653	4.7	109.3	82	1,738	227		7.7	15.4	4
15	Marshall Faulk M. Faulk	111	10,610	2,176	4.9	95.6	82	5,019	520	405	9.7	45.2	33
16	Derrick Henry D. Henry	110	11,883	2,260	5.3	108.0	111	1,441	143	185	10.1	13.1	5
17	Thurman Thomas T. Thomas	110	10,240	2,284	4.5	93.1	58	3,223	323	2	10.0	29.3	20
18	Fred Taylor F. Taylor	108	10,605	2,170	4.9	98.2	60	2,007	237	284	8.5	18.6	6
19	Ricky Watters R. Watters	108	9,513	2,201	4.3	88.1	67	3,241	369	159	8.8	30.0	10
20	John Riggins J. Riggins	106	9,373	2,228	4.2	88.4	88	1,206	150		8.0	11.4	8
21	Marshawn Lynch M. Lynch	101	9,003	1,958	4.6	89.1	71	1,614	201	274	8.0	16.0	8
22	Warrick Dunn W. Dunn	101	8,701	1,843	4.7	86.1	40	1,834	227	266	8.1	18.2	6
23	Eddie George E. George	100	9,268	2,396	3.9	92.7	59	1,648	197	195	8.4	16.5	7
24	Corey Dillon C. Dillon	99	9,737	2,076	4.7	98.4	68	1,406	183	201	7.7	14.2	6
25	Ottis Anderson O. Anderson	98	8,976	2,036	4.4	91.6	57	2,246	263		8.5	22.9	4

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Emmitt Smith had the most games with 50+ rushing yards, with 173 games.

Interpreted as:

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