who has the most sacks in a game since 2000

Since 2000, Khalil Mack, Adrian Clayborn and Osi Umenyiora are tied for the most sacks in a game, with 6 sacks.

Interpreted as:
Who has the most defensive sacks in a regular-season game since 2000?
NAMESCKDATETMOPPTKLASTCOMBSCKYINTINT YDSINT TDFFFRFR TD
1Khalil Mack
K. Mack
6.0
10/1/2023
vs
8
2
10
45
0
0
0
2
0
0
2Adrian Clayborn
A. Clayborn
6.0
11/12/2017
vs
6
0
6
32
0
0
0
2
1
0
3Osi Umenyiora
O. Umenyiora
6.0
9/30/2007
vs
6
0
6
38
0
0
0
2
0
0
4Aldon Smith
A. Smith
5.5
11/19/2012
vs
6
1
7
45
0
0
0
2
0
0
5Myles Garrett
M. Garrett
5.0
10/26/2025
@
6
0
6
33
0
0
0
1
0
0
6Chandler Jones
C. Jones
5.0
9/12/2021
@
6
0
6
46
0
0
0
2
0
0
7Haason Reddick
H. Reddick
5.0
12/13/2020
@
5
0
5
43
0
0
0
3
0
0
8Khalil Mack
K. Mack
5.0
12/13/2015
@
6
1
7
32
0
0
0
1
0
0
9Antwan Odom
A. Odom
5.0
9/20/2009
@
6
0
6
31
0
0
0
0
0
0
10Vonnie Holliday
V. Holliday
5.0
12/22/2002
vs
5
2
7
28
0
0
0
3
0
0
11Aidan Hutchinson
A. Hutchinson
4.5
9/15/2024
vs
4
1
5
37
0
0
0
1
0
0
12Myles Garrett
M. Garrett
4.5
9/26/2021
vs
6
1
7
24.5
0
0
0
0
0
0
13Justin Houston
J. Houston
4.5
9/19/2013
@
6
1
7
28
0
0
0
1
2
0
14Mario Williams
M. Williams
4.5
9/15/2013
vs
5
1
6
24.5
0
0
0
0
0
0
15Cameron Wake
C. Wake
4.5
9/30/2012
@
4
1
5
30.5
0
0
0
0
0
0
16Jared Allen
J. Allen
4.5
10/5/2009
vs
6
1
7
19.5
0
0
0
1
0
0
17Myles Garrett
M. Garrett
4.0
11/16/2025
vs
5
0
5
17
0
0
0
0
0
0
18Will McDonald IV
W. McDonald IV
4.0
11/9/2025
vs
4
1
5
32
0
0
0
0
0
0
19Tuli Tuipulotu
T. Tuipulotu
4.0
9/28/2025
@
7
3
10
19
0
0
0
1
0
0
20Trey Hendrickson
T. Hendrickson
4.0
11/3/2024
vs
4
0
4
37
0
0
0
1
0
0
21T.J. Watt
T.J. Watt
4.0
1/3/2022
vs
5
0
5
25
0
0
0
0
0
0
22Aaron Donald
A. Donald
4.0
10/11/2020
@
4
0
4
23
0
0
0
1
0
0
23Chandler Jones
C. Jones
4.0
12/22/2019
@
4
2
6
36
0
0
0
2
0
0
24Cameron Jordan
C. Jordan
4.0
11/28/2019
@
5
1
6
19
0
0
0
0
0
0
25Maxx Crosby
M. Crosby
4.0
11/17/2019
vs
4
1
5
42
0
0
0
1
0
0
StatMuse has game-level data for sacks going back to the 1982 season.

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