11 players were tied for the fewest interceptions with more than 0 intercepted passes in 2021, with 1 interception. The first three are Case Keenum, Colt McCoy and Geno Smith.
| NAME | INT | SEASON | TM | GP | CMP | ATT | PCT | YDS | AVG | YDS/G | TD | RTG | TD% | INT% | SCK | SCKY | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | C. Keenum | 1 | 2021 |  CLE | 7 | 47 | 72 | 65.3 | 462 | 6.4 | 66.0 | 3 | 91.3 | 4.2 | 1.4 | 5 | 29 |
| 2 |  | C. McCoy | 1 | 2021 |  ARI | 8 | 74 | 99 | 74.7 | 740 | 7.5 | 92.5 | 3 | 101.4 | 3.0 | 1.0 | 6 | 40 |
| 3 |  | G. Smith | 1 | 2021 |  SEA | 4 | 65 | 95 | 68.4 | 702 | 7.4 | 175.5 | 5 | 103.0 | 5.3 | 1.1 | 13 | 117 |
| 4 |  | M. Trubisky | 1 | 2021 |  BUF | 6 | 6 | 8 | 75.0 | 43 | 5.4 | 7.2 | 0 | 47.4 | 0.0 | 12.5 | 0 | 0 |
| 5 |  | C. Rush | 1 | 2021 |  DAL | 5 | 30 | 47 | 63.8 | 422 | 9.0 | 84.4 | 3 | 105.1 | 6.4 | 2.1 | 3 | 19 |
| 6 |  | M. Rudolph | 1 | 2021 |  PIT | 2 | 35 | 58 | 60.3 | 277 | 4.8 | 138.5 | 1 | 70.8 | 1.7 | 1.7 | 0 | 0 |
| 7 | | J. Wolford | 1 | 2021 |  LAR | 3 | 1 | 4 | 25.0 | 5 | 1.3 | 1.7 | 0 | 0.0 | 0.0 | 25.0 | 1 | 8 |
| 8 |  | D. Montgomery | 1 | 2021 |  CHI | 13 | 0 | 1 | 0.0 | 0 | 0.0 | 0.0 | 0 | 0.0 | 0.0 | 100.0 | 0 | 0 |
| 9 |  | G. Minshew | 1 | 2021 |  PHI | 4 | 41 | 60 | 68.3 | 439 | 7.3 | 109.8 | 4 | 104.8 | 6.7 | 1.7 | 5 | 31 |
| 10 | | J. Eason | 1 | 2021 |  IND | 1 | 2 | 5 | 40.0 | 25 | 5.0 | 25.0 | 0 | 16.7 | 0.0 | 20.0 | 0 | 0 |
| 11 | | F. Franks | 1 | 2021 |  ATL | 9 | 0 | 1 | 0.0 | 0 | 0.0 | 0.0 | 0 | 0.0 | 0.0 | 100.0 | 0 | 0 |
| 12 | | J. Johnson | 2 | 2021 | TOT | 4 | 57 | 85 | 67.1 | 638 | 7.5 | 159.5 | 5 | 99.0 | 5.9 | 2.4 | 3 | 23 |
| 13 |  | J. Rosen | 2 | 2021 | ATL | 4 | 2 | 11 | 18.2 | 19 | 1.7 | 4.8 | 0 | 0.0 | 0.0 | 18.2 | 0 | 0 |
| 14 |  | D. Lock | 2 | 2021 |  DEN | 6 | 67 | 111 | 60.4 | 787 | 7.1 | 131.2 | 2 | 80.4 | 1.8 | 1.8 | 9 | 52 |
| 15 | | I. Book | 2 | 2021 |  NO | 1 | 12 | 20 | 60.0 | 135 | 6.8 | 135.0 | 0 | 40.6 | 0.0 | 10.0 | 8 | 54 |
| 16 |  | T. Lance | 2 | 2021 |  SF | 6 | 41 | 71 | 57.7 | 603 | 8.5 | 100.5 | 5 | 97.3 | 7.0 | 2.8 | 4 | 15 |
| 17 |  | T. Siemian | 3 | 2021 | NO | 6 | 108 | 188 | 57.4 | 1,154 | 6.1 | 192.3 | 11 | 88.4 | 5.9 | 1.6 | 9 | 64 |
| 18 |  | J. Winston | 3 | 2021 | NO | 7 | 95 | 161 | 59.0 | 1,170 | 7.3 | 167.1 | 14 | 102.8 | 8.7 | 1.9 | 11 | 69 |
| 19 | | P.J. Walker | 3 | 2021 |  CAR | 5 | 36 | 66 | 54.5 | 362 | 5.5 | 72.4 | 1 | 56.5 | 1.5 | 4.5 | 7 | 47 |
| 20 |  | J. Love | 3 | 2021 |  GB | 6 | 36 | 62 | 58.1 | 411 | 6.6 | 68.5 | 2 | 68.7 | 3.2 | 4.8 | 3 | 23 |
| 21 | | J. Fromm | 3 | 2021 |  NYG | 3 | 27 | 60 | 45.0 | 210 | 3.5 | 70.0 | 1 | 38.9 | 1.7 | 5.0 | 6 | 33 |
| 22 |  | A. Rodgers | 4 | 2021 | GB | 16 | 366 | 531 | 68.9 | 4,115 | 7.7 | 257.2 | 37 | 111.9 | 7.0 | 0.8 | 30 | 188 |
| 23 |  | J. Brissett | 4 | 2021 |  MIA | 11 | 141 | 225 | 62.7 | 1,283 | 5.7 | 116.6 | 5 | 78.1 | 2.2 | 1.8 | 19 | 132 |
| 24 | | T. Huntley | 4 | 2021 |  BAL | 7 | 122 | 188 | 64.9 | 1,081 | 5.8 | 154.4 | 3 | 76.6 | 1.6 | 2.1 | 18 | 107 |
| 25 |  | C. Newton | 5 | 2021 | CAR | 8 | 69 | 126 | 54.8 | 684 | 5.4 | 85.5 | 4 | 64.4 | 3.2 | 4.0 | 10 | 83 |
StatMuse has season-level data for intercepted passes going back to the 1932 season.
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