Tom Brady had the most passing yards in 2021, with 5,316 yards.

	NAME	YDS	SEASON	TM	GP	CMP	ATT	PCT	AVG	YDS/G	TD	INT	RATE	TD%	INT%	SCK	SCKY
1	Tom Brady T. Brady	5,316	2021	TB	17	485	719	67.5	7.4	312.7	43	12	102.1	6.0	1.7	22	144
2	Justin Herbert J. Herbert	5,014	2021	LAC	17	443	672	65.9	7.5	294.9	38	15	97.7	5.7	2.2	31	214
3	Matthew Stafford M. Stafford	4,886	2021	LAR	17	404	601	67.2	8.1	287.4	41	17	102.9	6.8	2.8	30	243
4	Patrick Mahomes P. Mahomes	4,839	2021	KC	17	436	658	66.3	7.4	284.6	37	13	98.5	5.6	2.0	28	146
5	Derek Carr D. Carr	4,804	2021	LV	17	428	626	68.4	7.7	282.6	23	14	94.0	3.7	2.2	40	241
6	Joe Burrow J. Burrow	4,611	2021	CIN	16	366	520	70.4	8.9	288.2	34	14	108.3	6.5	2.7	51	370
7	Dak Prescott D. Prescott	4,483	2021	DAL	16	411	597	68.8	7.5	280.2	37	10	104.4	6.2	1.7	30	144
8	Josh Allen J. Allen	4,407	2021	BUF	17	409	646	63.3	6.8	259.2	36	15	92.2	5.6	2.3	26	164
9	Kirk Cousins K. Cousins	4,221	2021	MIN	16	372	561	66.3	7.5	263.8	33	7	103.1	5.9	1.2	28	197
10	Aaron Rodgers A. Rodgers	4,115	2021	GB	16	366	531	68.9	7.7	257.2	37	4	111.9	7.0	0.8	30	188
11	Matt Ryan M. Ryan	3,968	2021	ATL	17	375	560	67.0	7.1	233.4	20	12	90.4	3.6	2.1	40	274
12	Jimmy Garoppolo J. Garoppolo	3,810	2021	SF	15	301	441	68.3	8.6	254.0	20	12	98.7	4.5	2.7	29	201
13	Mac Jones M. Jones	3,801	2021	NE	17	352	521	67.6	7.3	223.6	22	13	92.5	4.2	2.5	28	241
14	Kyler Murray K. Murray	3,787	2021	ARI	14	333	481	69.2	7.9	270.5	24	10	100.6	5.0	2.1	31	286
15	Ben Roethlisberger B. Roethlisberger	3,740	2021	PIT	16	390	605	64.5	6.2	233.8	22	10	86.8	3.6	1.7	38	232
16	Ryan Tannehill R. Tannehill	3,734	2021	TEN	17	357	531	67.2	7.0	219.6	21	14	89.6	4.0	2.6	47	327
17	Trevor Lawrence T. Lawrence	3,641	2021	JAX	17	359	602	59.6	6.0	214.2	12	17	71.9	2.0	2.8	32	238
18	Carson Wentz C. Wentz	3,563	2021	IND	17	322	516	62.4	6.9	209.6	27	7	94.6	5.2	1.4	32	227
19	Taylor Heinicke T. Heinicke	3,419	2021	WAS	16	321	494	65.0	6.9	213.7	20	15	85.9	4.0	3.0	38	278
20	Jared Goff J. Goff	3,245	2021	DET	14	332	494	67.2	6.6	231.8	19	8	91.5	3.8	1.6	35	280
21	Jalen Hurts J. Hurts	3,144	2021	PHI	15	265	432	61.3	7.3	209.6	16	9	87.2	3.7	2.1	26	150
22	Russell Wilson R. Wilson	3,113	2021	SEA	14	259	400	64.8	7.8	222.4	25	6	103.1	6.3	1.5	33	266
23	Teddy Bridgewater T. Bridgewater	3,052	2021	DEN	14	285	426	66.9	7.2	218.0	18	7	94.9	4.2	1.6	31	211
24	Baker Mayfield B. Mayfield	3,010	2021	CLE	14	253	418	60.5	7.2	215.0	17	13	83.1	4.1	3.1	43	269
25	Lamar Jackson L. Jackson	2,882	2021	BAL	12	246	382	64.4	7.5	240.2	16	13	87.0	4.2	3.4	38	190