The San Francisco 49ers have a record of 21-15 against the Cardinals at home all-time.

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Regular season

	TEAM	DATE	REC	TM		OPP	RESULT	W%	TD	1DWN	OFF	OPP OFF	3DWN%	4DWN%
1	49ers	11/18/1951	0-1	SF	vs	CHC	L 21-27	.000	3	26	379	437
2	49ers	9/29/1957	0-1	SF	vs	CHC	L 10-20	.000	1	16	324	346
3	49ers	9/27/1964	0-1	SF	vs	STL	L 13-23	.000	1	14	235	296
4	49ers	9/22/1968	1-0	SF	vs	STL	W 35-17	1.000	5	22	395	228
5	49ers	10/6/1974	0-1	SF	vs	STL	L 9-34	.000	1	12	306	407
6	49ers	11/12/1978	0-1	SF	vs	STL	L 10-16	.000	1	16	264	335
7	49ers	9/14/1980	1-0	SF	vs	STL	W 24-21	1.000	3	19	392	342
8	49ers	11/9/1986	1-0	SF	vs	STL	W 43-17	1.000	5	23	460	364
9	49ers	10/18/1987	1-0	SF	vs	STL	W 34-28	1.000	5	28	448	324
10	49ers	11/17/1991	1-0	SF	vs	PHX	W 14-10	1.000	2	22	257	176	60.0
11	49ers	10/24/1993	1-0	SF	vs	PHX	W 28-14	1.000	4	26	428	429	50.0
12	49ers	10/1/2000	1-0	SF	vs	ARI	W 27-20	1.000	3	18	345	365	43.8
13	49ers	10/27/2002	1-0	SF	vs	ARI	W 38-28	1.000	5	18	357	420	50.0	100.0
14	49ers	12/7/2003	1-0	SF	vs	ARI	W 50-14	1.000	7	30	496	210	50.0	0.0
15	49ers	10/10/2004	1-0	SF	vs	ARI	W 31-28	1.000	3	28	448	320	40.0	100.0
16	49ers	12/4/2005	0-1	SF	vs	ARI	L 10-17	.000	1	11	220	404	22.2
17	49ers	12/24/2006	0-1	SF	vs	ARI	L 20-26	.000	2	14	223	372	22.2	100.0
18	49ers	9/10/2007	1-0	SF	vs	ARI	W 20-17	1.000	2	16	194	261	25.0	100.0
19	49ers	9/7/2008	0-1	SF	vs	ARI	L 13-23	.000	1	13	291	285	37.5
20	49ers	12/14/2009	1-0	SF	vs	ARI	W 24-9	1.000	3	18	327	245	50.0
21	49ers	1/2/2011	1-0	SF	vs	ARI	W 38-7	1.000	5	16	362	279	18.2
22	49ers	11/20/2011	1-0	SF	vs	ARI	W 23-7	1.000	2	25	431	229	38.1	100.0
23	49ers	12/30/2012	1-0	SF	vs	ARI	W 27-13	1.000	3	20	407	262	28.6	100.0
24	49ers	10/13/2013	1-0	SF	vs	ARI	W 32-20	1.000	3	20	387	403	28.6	100.0
25	49ers	12/28/2014	1-0	SF	vs	ARI	W 20-17	1.000	2	18	395	397	41.7
	Average							.583	2.9	20.5	355.3	324.8
	Total		21-15					.583	103	739	12,791	11,691

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More 49ers Stats

Team Leaders

PASS

492

Purdy

RUSH

91

McCaffrey

REC

103

Evans

Team Rankings

PPG

31.0

4th

OPP PPG

10.0

3rd

RUSH YDS/G

134.5

8th

PASS YDS/G

246.0

10th

2026 Division Standings

TEAM	W	L	PCT
49ers	2	0	1.000
Seahawks	2	0	1.000
Cardinals	1	1	.500
Rams	1	1	.500

Schedule

DATE	MATCHUP			TIME (ET)
Sun 9/27	ARI	@	SF	4:05 PM
Sun 10/4	DEN	@	SF	4:25 PM
Sun 10/11	SF	@	SEA	4:25 PM
Mon 10/19	WAS	@	SF	8:15 PM
Sun 10/25	SF	@	ATL	1:00 PM

Last Game

Dolphins

0 - 2

Final

49ers

2 - 0

Sun 20 Sep 2026

NFL 2026 Leaders

Pass Yards Leaders

844

Love

662

Shough

648

Young

Rush Yards Leaders

349

Robinson

290

Walker

212

Henry

Rec Yards Leaders

284

Watson

277

Smith-Njigba

274

London

Pass TD Leaders

6

Young

6

Love

6

Prescott

Rush TD Leaders

4

Taylor

4

Allen

4

Henry

Rec TD Leaders

4

Smith-Njigba

4

Watson

4

St. Brown

QB Rating Leaders

127.3

Lock

125.9

Dart

125.8

Allen

Sack Leaders

4.0

Rousseau

3.5

Watt

3.0

Hutchinson

NFL 2026 Rankings

PPG Rankings

38.5

35.5

32.0

31.0

Opp PPG Rankings

8.0

8.5

10.0

12.5

13.5

15.0

Total Yards Rankings

457.5

427.5

424.5

409.0

385.5

Rush Yards Rankings

212.5

186.0

173.0

157.0

155.0

144.5

Pass Yards Rankings

331.0

324.0

313.5

291.0

283.0

281.3

Sack Leaders

8.0

7.0

NFL Fantasy 2026

Fantasy RB Rankings

64.7

Robinson

49

Henry

48.9

Walker

Fantasy WR Rankings

52.4

Watson

51.7

Smith-Njigba

44.9

St. Brown

Fantasy TE Rankings

28.5

Kincaid

25.6

McBride

23.2

Kelce

Fantasy K Rankings

31

McPherson

27

McLaughlin

24

Butker

NFL 2026 Betting

Best Record ATS

2-0

Worst Record ATS

0-2

NFL 2026 Standings

NFC East	W	L	T	PCT
Eagles	2	0	0	1.000
Giants	1	1	0	.500
Cowboys	1	1	0	.500
Commanders	0	2	0	.000
NFC North	W	L	T	PCT
Vikings	2	0	0	1.000
Lions	1	1	0	.500
Bears	1	1	0	.500
Packers	1	2	0	.333
NFC South	W	L	T	PCT
Panthers	1	1	0	.500
Saints	1	1	0	.500
Falcons	1	2	0	.333
Buccaneers	0	2	0	.000
NFC West	W	L	T	PCT
Seahawks	2	0	0	1.000
49ers	2	0	0	1.000
Rams	1	1	0	.500
Cardinals	1	1	0	.500

AFC East	W	L	T	PCT
Bills	2	0	0	1.000
Patriots	1	1	0	.500
Jets	1	1	0	.500
Dolphins	0	2	0	.000
AFC North	W	L	T	PCT
Bengals	2	0	0	1.000
Ravens	1	1	0	.500
Steelers	1	1	0	.500
Browns	1	1	0	.500
AFC South	W	L	T	PCT
Jaguars	1	1	0	.500
Titans	0	2	0	.000
Texans	0	2	0	.000
Colts	0	2	0	.000
AFC West	W	L	T	PCT
Chiefs	2	0	0	1.000
Raiders	2	0	0	1.000
Broncos	1	1	0	.500
Chargers	0	2	0	.000