The San Francisco 49ers have a 22-15 record against the Cardinals at home all-time.

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Regular season

	TEAM	DATE	REC	TM		OPP	RESULT	W%	TD	1DWN	OFF	OPP OFF	3DWN%	4DWN%
1	49ers	11/18/1951	0-1	SF	vs	CHC	L 21-27	.000	3	26	379	437
2	49ers	9/29/1957	0-1	SF	vs	CHC	L 10-20	.000	1	16	324	346
3	49ers	9/27/1964	0-1	SF	vs	STL	L 13-23	.000	1	14	235	296
4	49ers	9/22/1968	1-0	SF	vs	STL	W 35-17	1.000	5	22	395	228
5	49ers	10/6/1974	0-1	SF	vs	STL	L 9-34	.000	1	12	306	407
6	49ers	11/12/1978	0-1	SF	vs	STL	L 10-16	.000	1	16	264	335
7	49ers	9/14/1980	1-0	SF	vs	STL	W 24-21	1.000	3	19	392	342
8	49ers	11/9/1986	1-0	SF	vs	STL	W 43-17	1.000	5	23	460	364
9	49ers	10/18/1987	1-0	SF	vs	STL	W 34-28	1.000	5	28	448	324
10	49ers	11/17/1991	1-0	SF	vs	PHX	W 14-10	1.000	2	22	257	176	60.0
11	49ers	10/24/1993	1-0	SF	vs	PHX	W 28-14	1.000	4	26	428	429	50.0
12	49ers	10/1/2000	1-0	SF	vs	ARI	W 27-20	1.000	3	18	345	365	43.8
13	49ers	10/27/2002	1-0	SF	vs	ARI	W 38-28	1.000	5	18	357	420	50.0	100.0
14	49ers	12/7/2003	1-0	SF	vs	ARI	W 50-14	1.000	7	30	496	210	50.0	0.0
15	49ers	10/10/2004	1-0	SF	vs	ARI	W 31-28	1.000	3	28	448	320	40.0	100.0
16	49ers	12/4/2005	0-1	SF	vs	ARI	L 10-17	.000	1	11	220	404	22.2
17	49ers	12/24/2006	0-1	SF	vs	ARI	L 20-26	.000	2	14	223	372	22.2	100.0
18	49ers	9/10/2007	1-0	SF	vs	ARI	W 20-17	1.000	2	16	194	261	25.0	100.0
19	49ers	9/7/2008	0-1	SF	vs	ARI	L 13-23	.000	1	13	291	285	37.5
20	49ers	12/14/2009	1-0	SF	vs	ARI	W 24-9	1.000	3	18	327	245	50.0
21	49ers	1/2/2011	1-0	SF	vs	ARI	W 38-7	1.000	5	16	362	279	18.2
22	49ers	11/20/2011	1-0	SF	vs	ARI	W 23-7	1.000	2	25	431	229	38.1	100.0
23	49ers	12/30/2012	1-0	SF	vs	ARI	W 27-13	1.000	3	20	407	262	28.6	100.0
24	49ers	10/13/2013	1-0	SF	vs	ARI	W 32-20	1.000	3	20	387	403	28.6	100.0
25	49ers	12/28/2014	1-0	SF	vs	ARI	W 20-17	1.000	2	18	395	397	41.7
	Average							.595	2.9	20.6	357.5	325.8
	Total		22-15					.595	108	762	13,228	12,056

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More 49ers Stats

Team Leaders

PASS

789

Purdy

RUSH

166

McCaffrey

REC

174

Kittle

Team Rankings

PPG

32.7

2nd

OPP PPG

16.7

3rd

RUSH YDS/G

136.3

6th

PASS YDS/G

263.0

9th

2026 Division Standings

TEAM	W	L	PCT
49ers	3	0	1.000
Seahawks	2	1	.667
Cardinals	1	2	.333
Rams	1	2	.333

Schedule

DATE	MATCHUP			TIME (ET)
Sun 10/4	DEN	@	SF	4:25 PM
Sun 10/11	SF	@	SEA	4:25 PM
Mon 10/19	WAS	@	SF	8:15 PM
Sun 10/25	SF	@	ATL	1:00 PM
Sun 11/8	LV	@	SF	4:05 PM

Last Game

Cardinals

1 - 2

Final

49ers

3 - 0

Sun 27 Sep 2026

NFL 2026 Leaders

Pass Yards Leaders

939

Young

917

Shough

872

Stafford

Rush Yards Leaders

360

Walker

349

Robinson

346

Cook

Rec Yards Leaders

405

Smith-Njigba

375

Olave

358

Adams

Pass TD Leaders

9

Purdy

9

Cousins

8

Shough

Rush TD Leaders

6

Allen

6

Henry

4

Gibbs

Rec TD Leaders

6

Smith-Njigba

5

St. Brown

4

Watson

QB Rating Leaders

133.1

Purdy

127.3

Lock

116.1

Goff

Sack Leaders

6.0

Rousseau

4.0

Anderson

4.0

Graham

NFL 2026 Rankings

PPG Rankings

33.7

32.7

31.0

30.7

29.7

Opp PPG Rankings

12.0

13.7

16.7

17.0

Total Yards Rankings

417.7

416.3

408.0

401.7

399.3

398.7

Rush Yards Rankings

184.3

173.0

167.3

155.0

153.3

136.3

Pass Yards Rankings

313.0

305.7

295.0

281.3

276.0

270.7

Sack Leaders

14.0

12.0

11.0

10.0

9.0

NFL Fantasy 2026

Fantasy RB Rankings

80.3

Gibbs

69.9

Henry

68.2

Walker

Fantasy WR Rankings

77.1

Smith-Njigba

52.8

St. Brown

52.4

Watson

Fantasy TE Rankings

35.4

Kittle

35.1

Kelce

33.3

Johnson

Fantasy K Rankings

42

McPherson

39

McLaughlin

38

Shrader

NFL 2026 Betting

Best Record ATS

3-0

2-0-1

2-1

Worst Record ATS

0-3

NFL 2026 Standings

NFC East	W	L	T	PCT
Eagles	2	1	0	.667
Giants	2	1	0	.667
Cowboys	1	2	0	.333
Commanders	1	2	0	.333
NFC North	W	L	T	PCT
Vikings	3	0	0	1.000
Lions	2	1	0	.667
Bears	2	1	0	.667
Packers	1	2	0	.333
NFC South	W	L	T	PCT
Panthers	1	2	0	.333
Saints	1	2	0	.333
Falcons	1	2	0	.333
Buccaneers	0	3	0	.000
NFC West	W	L	T	PCT
49ers	3	0	0	1.000
Seahawks	2	1	0	.667
Rams	1	2	0	.333
Cardinals	1	2	0	.333

AFC East	W	L	T	PCT
Bills	3	0	0	1.000
Jets	1	2	0	.333
Patriots	1	2	0	.333
Dolphins	0	3	0	.000
AFC North	W	L	T	PCT
Steelers	2	1	0	.667
Ravens	2	1	0	.667
Browns	2	1	0	.667
Bengals	2	1	0	.667
AFC South	W	L	T	PCT
Jaguars	2	1	0	.667
Colts	1	2	0	.333
Titans	0	3	0	.000
Texans	0	3	0	.000
AFC West	W	L	T	PCT
Chiefs	3	0	0	1.000
Raiders	3	0	0	1.000
Broncos	2	1	0	.667
Chargers	0	3	0	.000