The San Francisco 49ers had their most sacks in a game on November 23, 1980, on October 11, 1976 and on December 6, 1964, with 10 sacks.

Interpreted as:

49ers with most defensive sacks in a regular-season game all-time

	TEAM	SCK	DATE	TM		OPP	RESULT	TKL	AST	COMB	SCKY	INT	INT YDS	INT TD	FF	FR	FR TD
1	49ers	10.0	11/23/1980	SF	vs	NYG	W 12-0				67	1	13	0		0	0
2	49ers	10.0	10/11/1976	SF	@	LA	W 16-0				97	0	0	0		3	0
3	49ers	10.0	12/6/1964	SF	vs	LA	W 28-7				62	2	52	0		2	0
4	49ers	9.0	10/29/1989	SF	@	NYJ	W 23-10				82	0	0	0		2	0
5	49ers	9.0	9/22/1985	SF	@	RAI	W 34-10				71	2	33	0		1	1
6	49ers	9.0	11/13/1983	SF	vs	NO	W 27-0				77	2	10	0		1	0
7	49ers	9.0	11/23/1972	SF	@	DAL	W 31-10				66	2	23	1		2	1
8	49ers	8.0	11/1/2018	SF	vs	OAK	W 34-3	46	4	50	39	0	0	0	2	0	0
9	49ers	8.0	1/3/2010	SF	@	STL	W 28-6	55	2	57	58	0	0	0	0	0	0
10	49ers	8.0	10/25/1998	SF	@	STL	W 28-10				32	3	36	0		1	0
11	49ers	8.0	11/10/1997	SF	@	PHI	W 24-12				43	1	10	0		2	1
12	49ers	8.0	11/23/1986	SF	vs	ATL	W 20-0				80	1	0	0		0	0
13	49ers	8.0	11/25/1984	SF	@	NO	W 35-3				48	1	53	1		0	0
14	49ers	8.0	9/25/1983	SF	vs	ATL	W 24-20				59	0	0	0		1	0
15	49ers	8.0	10/23/1977	SF	vs	DET	W 28-7				67	2	80	0		0	0
16	49ers	8.0	10/23/1976	SF	vs	ATL	W 15-0				85	2	18	0		1	0
17	49ers	8.0	9/26/1971	SF	@	NO	W 38-20				49	1	0	0		1	0
18	49ers	8.0	12/16/1967	SF	vs	DAL	W 24-16				54	2	22	0		2	0
19	49ers	8.0	9/24/1967	SF	vs	ATL	W 38-7				75	1	0	0		0	0
20	49ers	8.0	11/1/1959	SF	vs	DET	W 33-7				75			0		2	0
21	49ers	8.0	12/11/1954	SF	vs	BAL	W 10-7				68			0		1	0
22	49ers	8.0	9/26/1954	SF	vs	WAS	W 41-7				72			1		3	0
23	49ers	7.0	12/8/2024	SF	vs	CHI	W 38-13	40	16	56	46	0	0	0	0	1	0
24	49ers	7.0	10/3/2022	SF	vs	LAR	W 24-9	50	18	68	54	1	52	1	1	1	0
25	49ers	7.0	10/27/2019	SF	vs	CAR	W 51-13	49	9	58	58	3	70	0	0	0	0

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Results may be incomplete. StatMuse has complete team, game-level data for sacks going back to the 1952 season.

More 49ers Stats

Team Leaders

PASS

2,151

Jones

RUSH

1,039

McCaffrey

REC

849

McCaffrey

Team Rankings

PPG

26.1

9th

OPP PPG

21.3

12th

RUSH YDS/G

104.3

25th

PASS YDS/G

259.2

5th

2025 Division Standings

TEAM	W	L	PCT
Seahawks	12	3	.800
Rams	11	4	.733
49ers	11	4	.733
Cardinals	3	12	.200

Schedule

DATE	MATCHUP			TIME (ET)
Sun 12/28	CHI	@	SF	8:20 PM
Sun 1/4	SEA	@	SF	1:00 PM

Last Game

49ers

11 - 4

Final

Colts

8 - 7

Mon 22 Dec 2025

NFL 2025 Leaders

Pass Yards Leaders

4,482

Prescott

4,233

Goff

4,179

Stafford

Rush Yards Leaders

1,532

Cook

1,489

Taylor

1,267

Achane

Rec Yards Leaders

1,637

Smith-Njigba

1,592

Nacua

1,420

Pickens

Pass TD Leaders

40

Stafford

33

Goff

30

Prescott

Rush TD Leaders

17

Taylor

13

Gibbs

13

Jacobs

Rec TD Leaders

14

Adams

11

St. Brown

10

Smith-Njigba

QB Rating Leaders

112.1

Stafford

108.5

Maye

107.0

Goff

Sack Leaders

22.0

Garrett

15.0

Burns

13.5

Hutchinson

NFL 2025 Rankings

PPG Rankings

30.5

29.5

28.9

28.4

27.9

Opp PPG Rankings

16.6

18.6

19.3

19.6

19.9

Total Yards Rankings

398.6

396.7

373.1

371.5

370.1

369.4

Rush Yards Rankings

158.9

152.1

147.9

134.2

126.3

125.3

Pass Yards Rankings

287.0

278.6

264.8

263.9

259.2

258.1

Sack Leaders

64.0

50.0

49.0

48.0

45.0

43.0

NFL Fantasy 2025

Fantasy RB Rankings

298

Taylor

284.8

McCaffrey

272.6

Gibbs

Fantasy WR Rankings

225.3

Smith-Njigba

219.3

Nacua

198

Pickens

Fantasy TE Rankings

169.8

McBride

118.3

Goedert

116

Kelce

Fantasy K Rankings

184

Myers

182.6

Aubrey

163

Dicker

NFL 2025 Betting

Best Record ATS

11-4

10-4-1

10-5

Worst Record ATS

5-10

5-9-1

6-10

NFL 2025 Standings

AFC East	W	L	T	PCT
Patriots - x	12	3	0	.800
Bills - x	11	4	0	.733
Dolphins - e	6	9	0	.400
Jets - e	3	12	0	.200
AFC North	W	L	T	PCT
Steelers	9	6	0	.600
Ravens	7	8	0	.467
Bengals - e	5	10	0	.333
Browns - e	3	12	0	.200
AFC South	W	L	T	PCT
Jaguars - x	11	4	0	.733
Texans	10	5	0	.667
Colts	8	7	0	.533
Titans - e	3	12	0	.200
AFC West	W	L	T	PCT
Broncos - x	13	3	0	.813
Chargers - x	11	4	0	.733
Chiefs - e	6	10	0	.375
Raiders - e	2	13	0	.133

NFC East	W	L	T	PCT
Eagles - y	10	5	0	.667
Cowboys - e	7	8	1	.469
Commanders - e	4	12	0	.250
Giants - e	2	13	0	.133
NFC North	W	L	T	PCT
Bears - x	11	4	0	.733
Packers - x	9	5	1	.633
Vikings - e	8	8	0	.500
Lions - e	8	8	0	.500
NFC South	W	L	T	PCT
Panthers	8	7	0	.533
Buccaneers	7	8	0	.467
Falcons - e	6	9	0	.400
Saints - e	5	10	0	.333
NFC West	W	L	T	PCT
Seahawks - x	12	3	0	.800
49ers - x	11	4	0	.733
Rams - x	11	4	0	.733
Cardinals - e	3	12	0	.200

NFL 2025 Scores & Schedule

Scores

DATE	MATCHUP			SCORE
Sat 9/20	NO	@	SEA	13-44
Sat 9/20	ARI	@	SF	15-16
Sat 9/20	DAL	@	CHI	14-31
Sat 9/20	KC	@	NYG	22-9
Sun 9/21	DET	@	BAL	38-30

Schedule

DATE	MATCHUP			TIME (ET)
Sat 12/27	HOU	@	LAC	4:30 PM
Sat 12/27	BAL	@	GB	8:00 PM
Sun 12/28	TB	@	MIA	1:00 PM
Sun 12/28	NE	@	NYJ	1:00 PM
Sun 12/28	PIT	@	CLE	1:00 PM

The San Francisco 49ers had their most sacks in a game on November 23, 1980, on October 11, 1976 and on December 6, 1964, with 10 sacks.

Interpreted as:

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2,151

1,039

849

NFL 2025 Leaders

4,482

4,233

4,179

1,532

1,489

1,267

1,637

1,592

1,420

40

33

30

17

13

13

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11

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112.1

108.5

107.0

22.0

15.0

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NFL 2025 Rankings

NFL Fantasy 2025

298

284.8

272.6

225.3

219.3

198

169.8

118.3

116

184

182.6

163

NFL 2025 Betting

NFL 2025 Standings

NFL 2025 Scores & Schedule

Scores

Schedule