Khalil Mack has the most sacks + tackles for loss in a game, with 11 against the Raiders on October 1, 2023.
Interpreted as:
Most defensive sacks+tfls by a player in a regular-season game ever| NAME | SCK+TFL | SCK | TFL | DATE | TM | OPP | TKL | AST | COMB | SCKY | INT | INT YDS | INT TD | FF | FR | FR TD | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | K. Mack | 11 | 6.0 | 5 | 10/1/2023 |  LAC | vs |  LV | 8 | 2 | 10 | 45 | 0 | 0 | 0 | 2 | 0 | 0 |
| 2 |  | M. Garrett | 10 | 5.0 | 5 | 10/26/2025 |  CLE | @ |  NE | 6 | 0 | 6 | 33 | 0 | 0 | 0 | 1 | 0 | 0 |
| 3 |  | A. Donald | 10 | 4.0 | 6 | 10/21/2018 |  LAR | @ |  SF | 8 | 1 | 9 | 29 | 0 | 0 | 0 | 1 | 1 | 0 |
| 4 |  | K. Mack | 10 | 5.0 | 5 | 12/13/2015 | OAK | @ |  DEN | 6 | 1 | 7 | 32 | 0 | 0 | 0 | 1 | 0 | 0 |
| 5 |  | A. Odom | 10 | 5.0 | 5 | 9/20/2009 |  CIN | @ |  GB | 6 | 0 | 6 | 31 | 0 | 0 | 0 | 0 | 0 | 0 |
| 6 | | O. Umenyiora | 10 | 6.0 | 4 | 9/30/2007 |  NYG | vs |  PHI | 6 | 0 | 6 | 38 | 0 | 0 | 0 | 2 | 0 | 0 |
| 7 | | A. Smith | 9.5 | 5.5 | 4 | 11/19/2012 | SF | vs |  CHI | 6 | 1 | 7 | 45 | 0 | 0 | 0 | 2 | 0 | 0 |
| 8 | | M. Garrett | 9 | 4.0 | 5 | 11/16/2025 | CLE | vs |  BAL | 5 | 0 | 5 | 17 | 0 | 0 | 0 | 0 | 0 | 0 |
| 9 | | T. Tuipulotu | 9 | 4.0 | 5 | 9/28/2025 | LAC | @ | NYG | 7 | 3 | 10 | 19 | 0 | 0 | 0 | 1 | 0 | 0 |
| 10 |  | C. Jones | 9 | 5.0 | 4 | 9/12/2021 |  ARI | @ |  TEN | 6 | 0 | 6 | 46 | 0 | 0 | 0 | 2 | 0 | 0 |
| 11 | | J. Bosa | 9 | 3.0 | 6 | 11/29/2020 | LAC | @ |  BUF | 8 | 1 | 9 | 17 | 0 | 0 | 0 | 0 | 1 | 0 |
| 12 | | A. Clayborn | 9 | 6.0 | 3 | 11/12/2017 |  ATL | vs |  DAL | 6 | 0 | 6 | 32 | 0 | 0 | 0 | 2 | 1 | 0 |
| 13 |  | J.J. Watt | 9 | 3.0 | 6 | 12/16/2012 |  HOU | vs |  IND | 10 | 0 | 10 | 22 | 0 | 0 | 0 | 1 | 0 | 0 |
| 14 | | C. Barwin | 9 | 4.0 | 5 | 11/27/2011 | HOU | @ |  JAX | 7 | 3 | 10 | 32 | 0 | 0 | 0 | 0 | 0 | 0 |
| 15 |  | D. Ware | 9 | 4.0 | 5 | 10/30/2011 | DAL | @ | PHI | 10 | 1 | 11 | 23 | 0 | 0 | 0 | 1 | 0 | 0 |
| 16 | | K. Williams | 9 | 4.0 | 5 | 10/12/2008 |  MIN | vs |  DET | 8 | 0 | 8 | 28 | 0 | 0 | 0 | 0 | 0 | 0 |
| 17 | | B. Berry | 9 | 4.0 | 5 | 11/14/2004 | ARI | vs | NYG | 7 | 0 | 7 | 22 | 0 | 0 | 0 | 0 | 0 | 0 |
| 18 | | A. Brown | 9 | 4.0 | 5 | 11/7/2004 | CHI | @ | NYG | 6 | 2 | 8 | 18 | 0 | 0 | 0 | 1 | 0 | 0 |
| 19 |  | A. Hutchinson | 8.5 | 4.5 | 4 | 9/15/2024 | DET | vs |  TB | 4 | 1 | 5 | 37 | 0 | 0 | 0 | 1 | 0 | 0 |
| 20 | | M. Garrett | 8.5 | 4.5 | 4 | 9/26/2021 | CLE | vs | CHI | 6 | 1 | 7 | 24.5 | 0 | 0 | 0 | 0 | 0 | 0 |
| 21 | | Z. Smith | 8.5 | 3.5 | 5 | 12/23/2019 | GB | @ | MIN | 6 | 1 | 7 | 32 | 0 | 0 | 0 | 0 | 0 | 0 |
| 22 |  | J. Houston | 8.5 | 4.5 | 4 | 9/19/2013 |  KC | @ | PHI | 6 | 1 | 7 | 28 | 0 | 0 | 0 | 1 | 2 | 0 |
| 23 | | M. Williams | 8.5 | 4.5 | 4 | 9/15/2013 | BUF | vs |  CAR | 5 | 1 | 6 | 24.5 | 0 | 0 | 0 | 0 | 0 | 0 |
| 24 | | C. Wake | 8.5 | 4.5 | 4 | 9/30/2012 |  MIA | @ | ARI | 4 | 1 | 5 | 30.5 | 0 | 0 | 0 | 0 | 0 | 0 |
| 25 |  | J. Allen | 8.5 | 4.5 | 4 | 10/5/2009 | MIN | vs | GB | 6 | 1 | 7 | 19.5 | 0 | 0 | 0 | 1 | 0 | 0 |
StatMuse has game-level data for tackles for loss going back to the 2001 season.
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