James Cook III had 216 all-purpose yards when scoring 2+ touchdowns versus the Panthers on October 26.
Interpreted as:
active rbs with 200+ total yds and 2+ total tds in a regular-season game| NAME | DATE | YDS | TD | TM | OPP | RUSH YDS | ATT | YPC | RUSH TD | REC YDS | REC | TRG | AVG | REC TD | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | J. Cook III | 10/26/2025 | 216 | 2 |  BUF | @ |  CAR | 216 | 19 | 11.4 | 2 | 0 | 0 | 0 | 0 | |
| 2 |  | J. Gibbs | 10/20/2025 | 218 | 2 |  DET | vs |  TB | 136 | 17 | 8.0 | 2 | 82 | 3 | 3 | 27.3 | 0 |
| 3 |  | C. McCaffrey | 10/19/2025 | 201 | 2 |  SF | vs |  ATL | 129 | 24 | 5.4 | 2 | 72 | 7 | 8 | 10.3 | 0 |
| 4 |  | J. Hill | 9/28/2025 | 250 | 2 |  BAL | @ |  KC | 76 | 3 | 25.3 | 1 | 41 | 5 | 6 | 8.2 | 1 |
| 5 |  | J. Taylor | 12/22/2024 | 218 | 3 |  IND | vs |  TEN | 218 | 29 | 7.5 | 3 | 0 | 0 | 0 | 0 | |
| 6 |  | S. Barkley | 11/24/2024 | 302 | 2 |  PHI | @ |  LAR | 255 | 26 | 9.8 | 2 | 47 | 4 | 4 | 11.8 | 0 |
| 7 | | S. Tucker | 10/13/2024 | 247 | 2 | TB | @ |  NO | 136 | 14 | 9.7 | 1 | 56 | 3 | 3 | 18.7 | 1 |
| 8 |  | D. Henry | 9/29/2024 | 209 | 2 | BAL | vs | BUF | 199 | 24 | 8.3 | 1 | 10 | 3 | 3 | 3.3 | 1 |
| 9 | | J. Cook III | 12/17/2023 | 221 | 2 | BUF | vs |  DAL | 179 | 25 | 7.2 | 1 | 42 | 2 | 3 | 21.0 | 1 |
| 10 |  | K. Williams | 11/26/2023 | 204 | 2 | LAR | @ |  ARI | 143 | 16 | 8.9 | 0 | 61 | 6 | 6 | 10.2 | 2 |
| 11 |  | D. Achane | 9/24/2023 | 233 | 4 |  MIA | vs |  DEN | 203 | 18 | 11.3 | 2 | 30 | 4 | 4 | 7.5 | 2 |
| 12 |  | J. Jacobs | 11/27/2022 | 303 | 2 |  LV | @ |  SEA | 229 | 33 | 6.9 | 2 | 74 | 6 | 7 | 12.3 | 0 |
| 13 |  | J. Mixon | 11/6/2022 | 211 | 5 |  CIN | vs | CAR | 153 | 22 | 7.0 | 4 | 58 | 4 | 5 | 14.5 | 1 |
| 14 |  | D. Henry | 10/30/2022 | 228 | 2 | TEN | @ |  HOU | 219 | 32 | 6.8 | 2 | 9 | 1 | 1 | 9.0 | 0 |
| 15 | | J. Taylor | 11/21/2021 | 204 | 5 | IND | @ | BUF | 185 | 32 | 5.8 | 4 | 19 | 3 | 3 | 6.3 | 1 |
| 16 | | J. Taylor | 11/4/2021 | 200 | 2 | IND | vs |  NYJ | 172 | 19 | 9.1 | 2 | 28 | 2 | 2 | 14.0 | 0 |
| 17 | | D. Henry | 9/19/2021 | 237 | 3 | TEN | @ | SEA | 182 | 35 | 5.2 | 3 | 55 | 6 | 6 | 9.2 | 0 |
| 18 | | J. Taylor | 1/3/2021 | 254 | 2 | IND | vs |  JAX | 253 | 30 | 8.4 | 2 | 1 | 1 | 2 | 1.0 | 0 |
| 19 | | D. Henry | 1/3/2021 | 250 | 2 | TEN | @ | HOU | 250 | 34 | 7.4 | 2 | 0 | 0 | 0 | 0 | |
| 20 | | D. Henry | 12/13/2020 | 222 | 2 | TEN | @ | JAX | 215 | 26 | 8.3 | 2 | 7 | 2 | 2 | 3.5 | 0 |
| 21 | | D. Henry | 10/18/2020 | 264 | 2 | TEN | vs | HOU | 212 | 22 | 9.6 | 2 | 52 | 2 | 5 | 26.0 | 0 |
| 22 |  | A. Jones Sr. | 9/20/2020 | 236 | 3 |  GB | vs | DET | 168 | 18 | 9.3 | 2 | 68 | 4 | 8 | 17.0 | 1 |
| 23 | | D. Henry | 12/29/2019 | 211 | 3 | TEN | @ | HOU | 211 | 32 | 6.6 | 3 | 0 | 0 | 0 | 0 | |
| 24 |  | S. Barkley | 12/22/2019 | 279 | 2 |  NYG | @ |  WAS | 189 | 22 | 8.6 | 1 | 90 | 4 | 4 | 22.5 | 1 |
| 25 | | A. Jones Sr. | 10/27/2019 | 226 | 2 | GB | @ | KC | 67 | 13 | 5.2 | 0 | 159 | 7 | 8 | 22.7 | 2 |
Results may be incomplete. StatMuse has complete game-level data for touchdowns going back to the 1950 season.
More Bills Stats
Team Rankings
PPG
29.4
3rd
OPP PPG
20.9
9th
RUSH YDS/G
161.5
1st
PASS YDS/G
235.9
14th
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