The Arizona Cardinals have a record of 48-51-1 against the AFC in the regular-season and playoffs at home all-time.
| TEAM | DATE | REC | TM | OPP | RESULT | W% | TD | 1DWN | OFF | OPP OFF | 3DWN% | 4DWN% | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | Cardinals | 11/1/1970 | 1-0 |  STL | vs |  HOU | W 44-0 | 1.000 | 5 | 20 | 454 | 160 | ||
| 2 | | Cardinals | 11/8/1970 | 1-0 | STL | vs |  BOS | W 31-0 | 1.000 | 4 | 15 | 283 | 195 | ||
| 3 | | Cardinals | 9/27/1971 | 1-0 | STL | vs |  NYJ | W 17-10 | 1.000 | 2 | 15 | 340 | 239 | ||
| 4 | | Cardinals | 10/1/1972 | 0-1 | STL | vs |  PIT | L 19-25 | .000 | 2 | 15 | 248 | 362 | ||
| 5 | | Cardinals | 10/7/1973 | 0-1 | STL | vs |  OAK | L 10-17 | .000 | 1 | 17 | 208 | 446 | ||
| 6 | | Cardinals | 11/4/1973 | 0-0-1 | STL | vs |  DEN | T 17-17 | .500 | 2 | 18 | 261 | 294 | ||
| 7 | | Cardinals | 9/29/1974 | 1-0 | STL | vs |  CLE | W 29-7 | 1.000 | 4 | 14 | 278 | 248 | ||
| 8 | | Cardinals | 12/1/1974 | 0-1 | STL | vs |  KC | L 13-17 | .000 | 2 | 15 | 252 | 240 | ||
| 9 | | Cardinals | 11/2/1975 | 1-0 | STL | vs | NE | W 24-17 | 1.000 | 3 | 18 | 273 | 274 | ||
| 10 | | Cardinals | 11/27/1975 | 0-1 | STL | vs |  BUF | L 14-32 | .000 | 2 | 16 | 210 | 392 | ||
| 11 | | Cardinals | 12/4/1976 | 1-0 | STL | vs |  BAL | W 24-17 | 1.000 | 3 | 20 | 375 | 279 | ||
| 12 | | Cardinals | 11/24/1977 | 0-1 | STL | vs |  MIA | L 14-55 | .000 | 2 | 13 | 210 | 503 | ||
| 13 | | Cardinals | 9/10/1978 | 0-1 | STL | vs | NE | L 6-16 | .000 | 1 | 9 | 193 | 441 | ||
| 14 | | Cardinals | 10/8/1978 | 0-1 | STL | vs | BAL | L 17-30 | .000 | 2 | 21 | 343 | 222 | ||
| 15 | | Cardinals | 9/16/1979 | 0-1 | STL | vs | PIT | L 21-24 | .000 | 2 | 12 | 212 | 398 | ||
| 16 | | Cardinals | 10/28/1979 | 0-1 | STL | vs | CLE | L 20-38 | .000 | 3 | 16 | 282 | 418 | ||
| 17 | | Cardinals | 11/23/1980 | 0-1 | STL | vs | KC | L 13-21 | .000 | 1 | 16 | 319 | 321 | ||
| 18 | | Cardinals | 9/6/1981 | 0-1 | STL | vs | MIA | L 7-20 | .000 | 1 | 14 | 203 | 292 | ||
| 19 | | Cardinals | 11/15/1981 | 1-0 | STL | vs | BUF | W 24-0 | 1.000 | 3 | 22 | 338 | 311 | ||
| 20 | | Cardinals | 11/13/1983 | 1-0 | STL | vs |  SEA | W 33-28 | 1.000 | 4 | 22 | 408 | 249 | ||
| 21 | | Cardinals | 11/20/1983 | 1-0 | STL | vs |  SD | W 44-14 | 1.000 | 6 | 18 | 378 | 315 | ||
| 22 | | Cardinals | 9/9/1984 | 1-0 | STL | vs | BUF | W 37-7 | 1.000 | 4 | 28 | 486 | 171 | ||
| 23 | | Cardinals | 9/30/1984 | 0-1 | STL | vs | MIA | L 28-36 | .000 | 4 | 24 | 445 | 552 | ||
| 24 | | Cardinals | 9/15/1985 | 1-0 | STL | vs |  CIN | W 41-27 | 1.000 | 5 | 27 | 447 | 370 | ||
| 25 | | Cardinals | 10/27/1985 | 0-1 | STL | vs | HOU | L 10-20 | .000 | 1 | 22 | 427 | 229 | ||
| Average | .485 | 2.6 | 18.9 | 318.5 | 322.5 | ||||||||||
| Total | 48-51-1 | .485 | 256 | 1,892 | 31,848 | 32,248 | |||||||||
More Cardinals Stats
Team Rankings
PPG
20.5
22nd
OPP PPG
18.5
6th
RUSH YDS/G
105.8
22nd
PASS YDS/G
185.5
28th
Rams 
Cardinals 
TEN 
IND 
DAL 
NFL 2025 Leaders
NFL 2025 Rankings
NFL Fantasy 2025
NFL 2025 Betting
NFL 2025 Division Standings
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
 Eagles | 4 | 0 | 0 | 1.000 |
 Commanders | 2 | 2 | 0 | .500 |
| NFC North | W | L | T | PCT |
 Lions | 3 | 1 | 0 | .750 |
 Packers | 2 | 1 | 1 | .625 |
| NFC South | W | L | T | PCT |
 Buccaneers | 3 | 1 | 0 | .750 |
 Falcons | 2 | 2 | 0 | .500 |
| NFC West | W | L | T | PCT |
 49ers | 3 | 1 | 0 | .750 |
| Seahawks | 3 | 1 | 0 | .750 |
Jaguars 
MIN 
HOU 
BAL 
NYG 
NO 
