The Detroit Lions have a 1-4-1 record against the Bills on the road all-time.

Regular season

	TEAM	DATE	REC	TM		OPP	RESULT	W%	TD	1DWN	OFF	OPP OFF	3DWN%	4DWN%
1	Lions	12/10/1972	0-0-1	DET	@	BUF	T 21-21	.500	3	14	260	418
2	Lions	12/22/1991	1-0	DET	@	BUF	W 17-14	1.000	2	22	356	275	8.3	0.0
3	Lions	10/5/1997	0-1	DET	@	BUF	L 13-22	.000	1	17	309	266	41.2	0.0
4	Lions	10/27/2002	0-1	DET	@	BUF	L 17-24	.000	2	16	282	343	33.3	0.0
5	Lions	11/14/2010	0-1	DET	@	BUF	L 12-14	.000	1	19	390	288	26.3	100.0
6	Lions	12/16/2018	0-1	DET	@	BUF	L 13-14	.000	2	14	313	312	38.5
	Average							.250	1.8	17.0	318.3	317.0		0.1
	Total		1-4-1					.250	11	102	1,910	1,902		42.9

More NFL News

NFL teams only need to look back a year to see how little a Week 1 loss might mean

Sep 16, 2026

Browns place running back Dylan Sampson on injured reserve

Sep 15, 2026

Ravens drop K Jake Moody from the practice squad after Tyler Loop's solid performance in the opener

Sep 15, 2026

Chargers lose KeAndre Lambert-Smith to injured reserve after Week 1 loss

Sep 15, 2026

Lawyers for victim in Packers running back Josh Jacobs' battery case file motion to seal evidence

Sep 15, 2026

A proud Broncos defense unravels: 28 missed tackles fuel a 31-10 loss at Arrowhead

Sep 15, 2026

More Lions Stats

Team Leaders

PASS

206

Goff

RUSH

156

Gibbs

REC

67

St. Brown

Team Rankings

PPG

31.0

8th

OPP PPG

30.0

22nd

RUSH YDS/G

165.0

5th

PASS YDS/G

206.0

17th

2026 Division Standings

TEAM	W	L	PCT
Bears	1	0	1.000
Lions	1	0	1.000
Vikings	1	0	1.000
Packers	0	1	.000

Schedule

DATE	MATCHUP			TIME (ET)
Thu 9/17	DET	@	BUF	8:15 PM
Sun 9/27	NYJ	@	DET	1:00 PM
Sun 10/4	DET	@	CAR	8:20 PM
Sun 10/11	DET	@	ARI	4:25 PM
Sun 10/25	GB	@	DET	4:25 PM

Last Game

Saints

0 - 1

Final

Lions

1 - 0

Sun 13 Sep 2026

NFL 2026 Leaders

Pass Yards Leaders

410

Shough

387

Love

361

Young

Rush Yards Leaders

173

Walker

156

Gibbs

144

Henry

Rec Yards Leaders

182

Olave

150

Flowers

147

Watson

Pass TD Leaders

4

Lawrence

3

Shough

3

Dart

Rush TD Leaders

3

Swift

3

Henry

2

Williams

Rec TD Leaders

2

Jeanty

2

Watson

2

St. Brown

QB Rating Leaders

150.6

Lawrence

134.2

Dart

130.5

Allen

Sack Leaders

2.0

Hutchinson

2.0

Watt

2.0

Paye

NFL 2026 Rankings

PPG Rankings

59.0

41.0

39.0

37.0

36.0

34.0

Opp PPG Rankings

7.0

10.0

13.0

Total Yards Rankings

552.0

506.0

478.0

469.0

419.0

409.0

Rush Yards Rankings

291.0

220.0

202.0

174.0

165.0

Pass Yards Rankings

410.0

387.0

361.0

334.0

324.0

277.0

Sack Leaders

5.0

4.0

NFL Fantasy 2026

Fantasy RB Rankings

34.3

Henry

31.4

Swift

31.1

Walker

Fantasy WR Rankings

26.7

Watson

25.8

Coker

23.2

Jefferson

Fantasy TE Rankings

19.8

Likely

19.7

Goedert

15.5

McBride

Fantasy K Rankings

19

McPherson

16

Ryland

15

Sanders

NFL 2026 Betting

Best Record ATS

1-0

Worst Record ATS

0-1

NFL 2026 Standings

NFC East	W	L	T	PCT
Giants	1	0	0	1.000
Eagles	1	0	0	1.000
Commanders	0	1	0	.000
Cowboys	0	1	0	.000
NFC North	W	L	T	PCT
Vikings	1	0	0	1.000
Bears	1	0	0	1.000
Lions	1	0	0	1.000
Packers	0	1	0	.000
NFC South	W	L	T	PCT
Falcons	0	1	0	.000
Buccaneers	0	1	0	.000
Saints	0	1	0	.000
Panthers	0	1	0	.000
NFC West	W	L	T	PCT
49ers	1	0	0	1.000
Cardinals	1	0	0	1.000
Seahawks	1	0	0	1.000
Rams	0	1	0	.000

AFC East	W	L	T	PCT
Jets	1	0	0	1.000
Bills	1	0	0	1.000
Patriots	0	1	0	.000
Dolphins	0	1	0	.000
AFC North	W	L	T	PCT
Ravens	1	0	0	1.000
Bengals	1	0	0	1.000
Steelers	1	0	0	1.000
Browns	0	1	0	.000
AFC South	W	L	T	PCT
Jaguars	1	0	0	1.000
Texans	0	1	0	.000
Titans	0	1	0	.000
Colts	0	1	0	.000
AFC West	W	L	T	PCT
Chiefs	1	0	0	1.000
Raiders	1	0	0	1.000
Chargers	0	1	0	.000
Broncos	0	1	0	.000