The San Francisco 49ers are 38-31 against the Cardinals all-time.

Showing:

Regular season

	TEAM	DATE	REC	TM		OPP	RESULT	W%	TD	1DWN	OFF	OPP OFF	3DWN%	4DWN%
1	49ers	11/18/1951	0-1	SF	vs	CHC	L 21-27	.000	3	26	379	437
2	49ers	9/29/1957	0-1	SF	vs	CHC	L 10-20	.000	1	16	324	346
3	49ers	11/25/1962	1-0	SF	@	STL	W 24-17	1.000	3	15	215	314
4	49ers	9/27/1964	0-1	SF	vs	STL	L 13-23	.000	1	14	235	296
5	49ers	9/22/1968	1-0	SF	vs	STL	W 35-17	1.000	5	22	395	228
6	49ers	10/24/1971	1-0	SF	@	STL	W 26-14	1.000	2	16	366	284
7	49ers	10/6/1974	0-1	SF	vs	STL	L 9-34	.000	1	12	306	407
8	49ers	10/31/1976	0-1	SF	@	STL	L 20-23	.000	3	23	382	373
9	49ers	11/12/1978	0-1	SF	vs	STL	L 10-16	.000	1	16	264	335
10	49ers	12/2/1979	0-1	SF	@	STL	L 10-13	.000	1	16	290	286
11	49ers	9/14/1980	1-0	SF	vs	STL	W 24-21	1.000	3	19	392	342
12	49ers	11/21/1982	1-0	SF	@	STL	W 31-20	1.000	4	22	448	254
13	49ers	9/18/1983	1-0	SF	@	STL	W 42-27	1.000	6	24	527	385
14	49ers	11/9/1986	1-0	SF	vs	STL	W 43-17	1.000	5	23	460	364
15	49ers	10/18/1987	1-0	SF	vs	STL	W 34-28	1.000	5	28	448	324
16	49ers	11/6/1988	0-1	SF	@	PHX	L 23-24	.000	2	22	357	355
17	49ers	11/17/1991	1-0	SF	vs	PHX	W 14-10	1.000	2	22	257	176	60.0
18	49ers	11/1/1992	0-1	SF	@	PHX	L 14-24	.000	2	19	330	342	14.3	0.0
19	49ers	10/24/1993	1-0	SF	vs	PHX	W 28-14	1.000	4	26	428	429	50.0
20	49ers	9/27/1999	1-0	SF	@	ARI	W 24-10	1.000	3	18	322	250	43.8
21	49ers	10/1/2000	1-0	SF	vs	ARI	W 27-20	1.000	3	18	345	365	43.8
22	49ers	10/27/2002	1-0	SF	vs	ARI	W 38-28	1.000	5	18	357	420	50.0	100.0
23	49ers	12/21/2002	1-0	SF	@	ARI	W 17-14	1.000	2	21	358	184	55.0	50.0
24	49ers	10/26/2003	0-1	SF	@	ARI	L 13-16	.000	2	15	255	314	50.0
25	49ers	12/7/2003	1-0	SF	vs	ARI	W 50-14	1.000	7	30	496	210	50.0	0.0
	Average							.551	2.8	19.8	344.4	337.6
	Total		38-31					.551	194	1,363	23,762	23,294

Unlock 2x data

More NFL News

A knee injury sends David Njoku to IR as the Chargers juggle a growing injury list

Sep 24, 2026

Pro Picks: Broncos will beat the Rams in a possible Super Bowl preview

Sep 24, 2026

Marvin Harrison Jr.'s 3rd season off to a slow start as concerns grow about the Cardinals' receiver

Sep 24, 2026

Commanders rally around Marcus Mariota with Jayden Daniels sidelined

Sep 23, 2026

QB Sam Darnold returns to practice, no decision yet on Seahawks' game at the Commanders

Sep 23, 2026

The 49ers lose another defensive tackle to injury with C.J. West going on IR

Sep 23, 2026

More 49ers Stats

Team Leaders

PASS

492

Purdy

RUSH

91

McCaffrey

REC

103

Evans

Team Rankings

PPG

31.0

4th

OPP PPG

10.0

3rd

RUSH YDS/G

134.5

8th

PASS YDS/G

246.0

10th

2026 Division Standings

TEAM	W	L	PCT
49ers	2	0	1.000
Seahawks	2	0	1.000
Cardinals	1	1	.500
Rams	1	1	.500

Schedule

DATE	MATCHUP			TIME (ET)
Sun 9/27	ARI	@	SF	4:05 PM
Sun 10/4	DEN	@	SF	4:25 PM
Sun 10/11	SF	@	SEA	4:25 PM
Mon 10/19	WAS	@	SF	8:15 PM
Sun 10/25	SF	@	ATL	1:00 PM

Last Game

Dolphins

0 - 2

Final

49ers

2 - 0

Sun 20 Sep 2026

NFL 2026 Leaders

Pass Yards Leaders

662

Shough

648

Young

627

Stroud

Rush Yards Leaders

290

Walker

212

Henry

208

Gibbs

Rec Yards Leaders

277

Smith-Njigba

268

Olave

225

Kincaid

Pass TD Leaders

6

Young

6

Prescott

6

Goff

Rush TD Leaders

4

Taylor

4

Allen

4

Henry

Rec TD Leaders

4

Smith-Njigba

4

St. Brown

3

Watson

QB Rating Leaders

127.3

Lock

125.9

Dart

125.8

Allen

Sack Leaders

4.0

Rousseau

3.5

Watt

3.0

Hutchinson

NFL 2026 Rankings

PPG Rankings

38.5

35.5

32.0

31.0

Opp PPG Rankings

8.0

8.5

10.0

12.5

13.5

15.0

Total Yards Rankings

457.5

427.5

424.5

409.0

385.5

Rush Yards Rankings

212.5

186.0

157.0

155.0

144.5

142.5

Pass Yards Rankings

331.0

324.0

313.5

291.0

283.0

279.5

Sack Leaders

8.0

7.0

NFL Fantasy 2026

Fantasy RB Rankings

49

Henry

48.9

Walker

47.3

Taylor

Fantasy WR Rankings

51.7

Smith-Njigba

44.9

St. Brown

37.7

Lamb

Fantasy TE Rankings

28.5

Kincaid

25.6

McBride

23.2

Kelce

Fantasy K Rankings

31

McPherson

27

McLaughlin

24

Butker

NFL 2026 Betting

Best Record ATS

2-0

Worst Record ATS

0-2

NFL 2026 Standings

NFC East	W	L	T	PCT
Eagles	2	0	0	1.000
Giants	1	1	0	.500
Cowboys	1	1	0	.500
Commanders	0	2	0	.000
NFC North	W	L	T	PCT
Vikings	2	0	0	1.000
Lions	1	1	0	.500
Bears	1	1	0	.500
Packers	1	1	0	.500
NFC South	W	L	T	PCT
Panthers	1	1	0	.500
Saints	1	1	0	.500
Buccaneers	0	2	0	.000
Falcons	0	2	0	.000
NFC West	W	L	T	PCT
Seahawks	2	0	0	1.000
49ers	2	0	0	1.000
Rams	1	1	0	.500
Cardinals	1	1	0	.500

AFC East	W	L	T	PCT
Bills	2	0	0	1.000
Patriots	1	1	0	.500
Jets	1	1	0	.500
Dolphins	0	2	0	.000
AFC North	W	L	T	PCT
Bengals	2	0	0	1.000
Ravens	1	1	0	.500
Steelers	1	1	0	.500
Browns	1	1	0	.500
AFC South	W	L	T	PCT
Jaguars	1	1	0	.500
Titans	0	2	0	.000
Texans	0	2	0	.000
Colts	0	2	0	.000
AFC West	W	L	T	PCT
Chiefs	2	0	0	1.000
Raiders	2	0	0	1.000
Broncos	1	1	0	.500
Chargers	0	2	0	.000