The San Francisco 49ers had their highest over/under line in the 2021 NFC Wild Card game on the road against the Cowboys on January 16, 2022, at 51 points.
| TEAM | DATE | TM | OPP | RESULT | SPREAD | ATS DIFF | O/U | O/U DIFF | TD | 1DWN | OFF | OPP OFF | 3DWN% | 4DWN% | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | 49ers | 1/16/2022 | +153 | @ | -181 | W 23-17 | +3.5 | +9.5 (Y) | 51 | -11 (U) | 2 | 21 | 341 | 307 | 46.2 | |||
| 2 | | 49ers | 12/12/2021 | -128 | @ | +106 | W 26-23 | -1.5 | +1.5 (Y) | 49 | 0 (P) | 3 | 21 | 355 | 397 | 33.3 | |||
| 3 | | 49ers | 9/19/2021 | -150 | @ | +127 | W 17-11 | -3 | +3 (Y) | 49 | -21 (U) | 2 | 23 | 306 | 328 | 42.9 | 100.0 | ||
| 4 | | 49ers | 10/10/2021 | +208 | @ | -257 | L 10-17 | +5.5 | -1.5 (N) | 48.5 | -21.5 (U) | 1 | 19 | 338 | 304 | 27.3 | 20.0 | ||
| 5 | | 49ers | 1/22/2022 | +208 | @ | -254 | W 13-10 | +5.5 | +8.5 (Y) | 47 | -24 (U) | 1 | 12 | 212 | 263 | 36.4 | 0.0 | ||
| 6 | | 49ers | 1/9/2022 | +151 | @ | -178 | W 27-24 | +3.5 | +6.5 (Y) | 46.5 | +4.5 (O) | 3 | 23 | 449 | 265 | 64.3 | |||
| 7 | | 49ers | 1/30/2022 | +155 | @ | -183 | L 17-20 | +3.5 | +0.5 (Y) | 45.5 | -8.5 (U) | 2 | 16 | 282 | 396 | 33.3 | |||
| 8 | | 49ers | 12/23/2021 | -175 | @ | +147 | L 17-20 | -3.5 | -6.5 (N) | 45.5 | -8.5 (U) | 2 | 22 | 389 | 278 | 37.5 | 50.0 | ||
| 9 | | 49ers | 11/21/2021 | -290 | @ | +233 | W 30-10 | -6.5 | +13.5 (Y) | 45.5 | -5.5 (U) | 3 | 25 | 333 | 200 | 50.0 | 100.0 | ||
| 10 | | 49ers | 9/12/2021 | -371 | @ | +285 | W 41-33 | -7.5 | +0.5 (Y) | 45 | +29 (O) | 5 | 21 | 442 | 430 | 33.3 | |||
| 11 | | 49ers | 12/5/2021 | -143 | @ | +122 | L 23-30 | -2.5 | -9.5 (N) | 44.5 | +8.5 (O) | 3 | 17 | 365 | 327 | 30.0 | 50.0 | ||
| 12 | | 49ers | 10/31/2021 | -210 | @ | +172 | W 33-22 | -4.5 | +6.5 (Y) | 40 | +15 (O) | 3 | 21 | 467 | 324 | 40.0 | 100.0 |
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More 49ers Stats
Team Leaders 
PASS
789
Purdy
RUSH
166
McCaffrey
REC
174
Kittle
Team Rankings
PPG
32.7
2nd
OPP PPG
16.7
3rd
RUSH YDS/G
136.3
6th
PASS YDS/G
263.0
9th
DEN
WAS
ATL
LV
NFL 2026 Leaders
NFL 2026 Rankings
NFL Fantasy 2026
NFL 2026 Betting
NFL 2026 Standings
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
2 | 1 | 0 | .667 | |
2 | 1 | 0 | .667 | |
1 | 2 | 0 | .333 | |
1 | 2 | 0 | .333 | |
| NFC North | W | L | T | PCT |
3 | 0 | 0 | 1.000 | |
2 | 1 | 0 | .667 | |
2 | 1 | 0 | .667 | |
1 | 2 | 0 | .333 | |
| NFC South | W | L | T | PCT |
1 | 2 | 0 | .333 | |
1 | 2 | 0 | .333 | |
1 | 2 | 0 | .333 | |
0 | 3 | 0 | .000 | |
| NFC West | W | L | T | PCT |
3 | 0 | 0 | 1.000 | |
2 | 1 | 0 | .667 | |
1 | 2 | 0 | .333 | |
1 | 2 | 0 | .333 |
Giants
Vikings
Bears
Panthers
Saints
Buccaneers| AFC East | W | L | T | PCT |
|---|---|---|---|---|
3 | 0 | 0 | 1.000 | |
1 | 2 | 0 | .333 | |
1 | 2 | 0 | .333 | |
0 | 3 | 0 | .000 | |
| AFC North | W | L | T | PCT |
3 | 1 | 0 | .750 | |
2 | 1 | 0 | .667 | |
2 | 1 | 0 | .667 | |
2 | 2 | 0 | .500 | |
| AFC South | W | L | T | PCT |
2 | 1 | 0 | .667 | |
1 | 2 | 0 | .333 | |
0 | 3 | 0 | .000 | |
0 | 3 | 0 | .000 | |
| AFC West | W | L | T | PCT |
3 | 0 | 0 | 1.000 | |
3 | 0 | 0 | 1.000 | |
2 | 1 | 0 | .667 | |
0 | 3 | 0 | .000 |
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