Tom Brady was 13-6 with the Buccaneers against the NFC South in the regular-season and playoffs in his career.
| NAME | DATE | REC | TM | OPP | W% | CMP | ATT | PCT | YDS | AVG | TD | INT | RTG | TD% | INT% | SCK | SCKY | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | T. Brady | 9/13/2020 | 0-1 |  TB | @ |  NO | .000 | 23 | 36 | 63.9 | 239 | 6.6 | 2 | 2 | 78.4 | 5.6 | 5.6 | 3 | 15 |
| 2 | | T. Brady | 9/20/2020 | 1-0 | TB | vs |  CAR | 1.000 | 23 | 35 | 65.7 | 217 | 6.2 | 1 | 1 | 80.3 | 2.9 | 2.9 | 0 | 0 |
| 3 | | T. Brady | 11/8/2020 | 0-1 | TB | vs | NO | .000 | 22 | 38 | 57.9 | 209 | 5.5 | 0 | 3 | 40.4 | 0.0 | 7.9 | 3 | 23 |
| 4 | | T. Brady | 11/15/2020 | 1-0 | TB | @ | CAR | 1.000 | 28 | 39 | 71.8 | 341 | 8.7 | 3 | 0 | 124.0 | 7.7 | 0.0 | 1 | 7 |
| 5 | | T. Brady | 12/20/2020 | 1-0 | TB | @ |  ATL | 1.000 | 31 | 45 | 68.9 | 390 | 8.7 | 2 | 0 | 110.4 | 4.4 | 0.0 | 3 | 25 |
| 6 | | T. Brady | 1/3/2021 | 1-0 | TB | vs | ATL | 1.000 | 26 | 41 | 63.4 | 399 | 9.7 | 4 | 1 | 117.8 | 9.8 | 2.4 | 1 | 8 |
| 7 | | T. Brady | 1/17/2021 | 1-0 | TB | @ | NO | 1.000 | 18 | 33 | 54.5 | 199 | 6.0 | 2 | 0 | 92.9 | 6.1 | 0.0 | 1 | 10 |
| 8 | | T. Brady | 9/19/2021 | 1-0 | TB | vs | ATL | 1.000 | 24 | 36 | 66.7 | 276 | 7.7 | 5 | 0 | 129.2 | 13.9 | 0.0 | 3 | 17 |
| 9 | | T. Brady | 10/31/2021 | 0-1 | TB | @ | NO | .000 | 28 | 40 | 70.0 | 375 | 9.4 | 4 | 2 | 112.0 | 10.0 | 5.0 | 3 | 25 |
| 10 | | T. Brady | 12/5/2021 | 1-0 | TB | @ | ATL | 1.000 | 38 | 51 | 74.5 | 368 | 7.2 | 4 | 1 | 112.2 | 7.8 | 2.0 | 0 | 0 |
| 11 | | T. Brady | 12/19/2021 | 0-1 | TB | vs | NO | .000 | 26 | 48 | 54.2 | 214 | 4.5 | 0 | 1 | 57.1 | 0.0 | 2.1 | 4 | 30 |
| 12 | | T. Brady | 12/26/2021 | 1-0 | TB | @ | CAR | 1.000 | 18 | 30 | 60.0 | 232 | 7.7 | 1 | 0 | 95.4 | 3.3 | 0.0 | 0 | 0 |
| 13 | | T. Brady | 1/9/2022 | 1-0 | TB | vs | CAR | 1.000 | 29 | 37 | 78.4 | 326 | 8.8 | 3 | 0 | 130.4 | 8.1 | 0.0 | 1 | 2 |
| 14 | | T. Brady | 9/18/2022 | 1-0 | TB | @ | NO | 1.000 | 18 | 34 | 52.9 | 190 | 5.6 | 1 | 0 | 79.3 | 2.9 | 0.0 | 1 | 2 |
| 15 | | T. Brady | 10/9/2022 | 1-0 | TB | vs | ATL | 1.000 | 35 | 52 | 67.3 | 351 | 6.8 | 1 | 0 | 92.7 | 1.9 | 0.0 | 0 | 0 |
| 16 | | T. Brady | 10/23/2022 | 0-1 | TB | @ | CAR | .000 | 32 | 49 | 65.3 | 290 | 5.9 | 0 | 0 | 81.2 | 0.0 | 0.0 | 1 | 14 |
| 17 | | T. Brady | 12/5/2022 | 1-0 | TB | vs | NO | 1.000 | 36 | 54 | 66.7 | 281 | 5.2 | 2 | 1 | 84.0 | 3.7 | 1.9 | 1 | 7 |
| 18 | | T. Brady | 1/1/2023 | 1-0 | TB | vs | CAR | 1.000 | 34 | 45 | 75.6 | 432 | 9.6 | 3 | 0 | 127.3 | 6.7 | 0.0 | 3 | 21 |
| 19 | | T. Brady | 1/8/2023 | 0-1 | TB | @ | ATL | .000 | 13 | 17 | 76.5 | 84 | 4.9 | 1 | 0 | 106.0 | 5.9 | 0.0 | 0 | 0 |
| Average | .684 | 26.4 | 40.0 | 66.1 | 284.9 | 7.1 | 2.1 | 0.6 | 97.3 | 5.1 | 1.6 | 1.5 | 10.8 | |||||||
| Total | 13-6 | .684 | 502 | 760 | 66.1 | 5,413 | 7.1 | 39 | 12 | 97.3 | 5.1 | 1.6 | 29 | 206 |
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| NFC East | W | L | T | PCT |
|---|---|---|---|---|
 Eagles | 14 | 3 | 0 | .824 |
 Commanders | 12 | 5 | 0 | .706 |
| NFC North | W | L | T | PCT |
 Lions | 15 | 2 | 0 | .882 |
 Vikings | 14 | 3 | 0 | .824 |
| NFC South | W | L | T | PCT |
| Buccaneers | 10 | 7 | 0 | .588 |
| Falcons | 8 | 9 | 0 | .471 |
| NFC West | W | L | T | PCT |
 Rams | 10 | 7 | 0 | .588 |
 Seahawks | 10 | 7 | 0 | .588 |
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