Blaine Stoughton had the fewest games with 250+ goals and more than 0 games played, with 526 games.

Interpreted as:

fewest regular-season games by a player to reach 250 or more career goals

	NAME	GP	G	A	P	+/-	PIM	PPG	PPA	SHG	SHA	GWG	OTG	S	S%	FOW	FO	FOW%	HIT	BKS	TKA	GVA	TOI/GP
1	Blaine Stoughton B. Stoughton	526	258	191	449	-93	204	62	49	5	3	31	1	1,324	19.5
2	Howie Morenz H. Morenz	550	271	205	476		562	5	15	1	0	45	9
3	Kent Nilsson K. Nilsson	553	264	422	686	-25	116	97	179	16	8	28	1	1,374	19.2
4	Jake Guentzel J. Guentzel	600	268	303	571	+87	256	66	83	2	1	36	5	1,710	15.7	312	683	45.7	628	326	279	280	19:15
5	Kyle Connor K. Connor	613	284	298	582	-9	139	67	99	7	1	60	12	1,926	14.7	25	74	33.8	174	202	366	341	19:36
6	Alex DeBrincat A. DeBrincat	614	253	257	510	-57	175	87	89	1	0	32	12	1,777	14.2	140	333	42.0	513	238	345	351	18:11
7	Jimmy Carson J. Carson	626	275	286	561	-20	254	110	104	1	0	31	0	1,567	17.5
8	Auston Matthews A. Matthews	629	401	326	727	+151	134	104	99	2	1	63	12	2,534	15.8	4,977	9,338	53.3	441	625	591	490	19:52
9	Anton Stastny A. Stastny	650	252	384	636	+11	150	80	126	0	0	31	1	1,405	17.9
10	Nels Stewart N. Stewart	650	324	191	515		955	27	28	0	1	70	11
11	Mats Naslund M. Naslund	651	251	383	634	+119	111	68	143	2	1	35	3	1,360	18.5
12	Mikko Rantanen M. Rantanen	652	294	411	705	+91	408	103	151	0	0	47	5	1,840	16.0	991	1,949	50.8	410	345	392	349	20:25
13	Tim Kerr T. Kerr	655	370	304	674	+77	596	149	104	0	0	46	1	1,985	18.6
14	Aurel Joliat A. Joliat	655	269	194	463		771	11	9	0	2	65	9
15	Brayden Point B. Point	657	306	329	635	+77	149	105	96	3	2	63	12	1,630	18.8	3,391	6,928	48.9	297	332	315	246	19:08
16	Bobby Orr B. Orr	657	270	645	915	+582	953	76	248	16	31	26	0	3,058	8.8
17	Sylvain Turgeon S. Turgeon	669	269	226	495	-108	691	99	91	0	0	29	3	1,985	13.6
18	Sebastian Aho S. Aho	677	283	348	631	+121	296	68	122	20	11	64	16	1,873	15.1	3,774	7,338	51.4	515	202	488	562	19:05
19	Ziggy Palffy Z. Palffy	684	329	384	713	+83	322	92	164	19	7	45	5	2,136	15.4	14	36	38.9	181	128	228	328	20:32
20	William Nylander W. Nylander	685	262	350	612	+34	184	74	125	3	1	47	13	2,010	13.0	1,039	2,062	50.4	171	194	468	395	17:47
21	Richard Martin R. Martin	685	384	317	701	+14	477	115	104	0	0	47	0	2,526	15.2
22	Tony Tanti T. Tanti	697	287	273	560	-69	661	118	97	2	1	29	3	1,835	15.6
23	Pavel Bure P. Bure	702	437	342	779	+42	484	121	115	34	15	59	6	3,130	14.0	3	17	17.6	76	70	148	222	24:37
24	Bill Mosienko B. Mosienko	711	258	282	540		133	39	49	2	3	28	0
25	Connor McDavid C. McDavid	712	361	721	1,082	+168	276	87	277	8	9	72	16	2,407	15.0	3,935	8,242	47.7	533	280	663	652	21:44