16 players are tied for the most career hat tricks by an active defenseman, with 1 hat trick. The first three are Cale Makar, Jakob Chychrun and Tony DeAngelo.

most regular-season hat tricks by a defenseman NHL active players

	NAME	HT	GP	G	A	P	+/-	PIM	PPG	PPA	SHG	SHA	GWG	OTG	S	S%	FOW	FO	FOW%	HIT	BKS	TKA	GVA	TOI/GP
1	Cale Makar C. Makar	1	409	120	326	446	+147	116	41	145	3	4	25	6	1,153	10.4	0	0		351	573	304	317	24:49
2	Jakob Chychrun J. Chychrun	1	555	99	174	273	-43	366	34	44	0	0	17	4	1,341	7.4	0	0		643	835	198	456	21:20
3	Tony DeAngelo T. DeAngelo	1	420	53	181	234	-40	343	13	80	0	0	8	4	876	6.1	1	1	100.0	291	449	115	366	19:21
4	MacKenzie Weegar M. Weegar	1	566	59	196	255	+99	411	8	40	1	8	9	1	1,096	5.4	1	2	50.0	1,255	1,024	346	608	21:04
5	Zach Werenski Z. Werenski	1	580	117	277	394	+13	146	26	94	2	3	17	7	1,633	7.2	0	0		311	769	284	420	23:56
6	Brandon Montour B. Montour	1	610	87	214	301	+23	456	17	76	3	1	20	4	1,392	6.3	0	0		684	684	190	445	21:20
7	Jaccob Slavin J. Slavin	1	747	55	244	299	+166	94	7	21	4	14	9	3	1,288	4.3	0	1	0.0	433	1,244	701	454	22:26
8	Hampus Lindholm H. Lindholm	1	769	73	241	314	+146	449	14	67	1	4	13	3	1,304	5.6	2	8	25.0	699	986	272	655	22:20
9	Rasmus Ristolainen R. Ristolainen	1	776	56	248	304	-179	383	15	105	1	4	8	5	1,455	3.8	1	2	50.0	1,900	1,254	192	425	22:39
10	Nikita Zadorov N. Zadorov	1	739	52	120	172	+39	860	2	7	0	3	5	1	889	5.8	1	1	100.0	2,046	796	217	500	18:26
11	Dougie Hamilton D. Hamilton	1	849	155	353	508	+77	532	49	118	1	2	34	9	2,430	6.4	1	4	25.0	989	942	257	701	20:37
12	Justin Faulk J. Faulk	1	995	133	333	466	-67	482	48	102	3	5	33	4	2,315	5.7	0	1	0.0	1,587	1,357	579	681	23:00
13	Cam Fowler C. Fowler	1	1,057	105	393	498	-118	273	40	145	4	6	19	5	1,659	6.3	2	3	66.7	483	1,432	348	662	23:08
14	Jared Spurgeon J. Spurgeon	1	949	118	302	420	+115	160	35	100	0	6	23	5	1,561	7.6	1	3	33.3	820	1,637	268	326	22:06
15	Erik Karlsson E. Karlsson	1	1,099	201	681	882	-117	490	44	264	2	5	38	12	3,003	6.7	0	4	0.0	780	1,444	861	1,309	25:12
16	Shea Weber S. Weber	1	1,038	224	365	589	+79	714	106	133	5	6	35	7	2,765	8.1	0	0		2,212	1,691	372	737	24:03