Since 1999-00, Alex Pietrangelo has made the most assists for the Blues, with 341 assists.

	NAME	A	GP	G	P	+/-	PIM	PPG	PPA	SHG	SHA	GWG	OTG	S	S%	FOW	FO	FOW%	HIT	BKS	TKA	GVA	TOI/GP
1	Alex Pietrangelo A. Pietrangelo	341	758	109	450	+77	241	34	116	0	8	25	3	1,801	6.1	0	2	0.0	515	1,375	438	378	24:38
2	Alexander Steen A. Steen	301	765	195	496	+50	348	42	105	9	3	35	3	1,863	10.5	1,068	2,313	46.2	454	482	338	213	18:20
3	Robert Thomas R. Thomas	299	485	110	409	+45	152	24	77	5	3	19	3	752	14.6	3,334	6,460	51.6	91	206	322	350	17:39
4	Vladimir Tarasenko V. Tarasenko	291	644	262	553	+57	185	65	89	1	1	44	10	2,059	12.7	17	44	38.6	515	252	262	229	17:31
5	Brayden Schenn B. Schenn	272	612	173	445	-25	391	47	66	1	0	33	9	1,223	14.1	3,604	7,301	49.4	1,173	297	318	333	18:22
6	David Perron D. Perron	269	673	196	465	+62	454	55	95	3	3	29	6	1,379	14.2	75	190	39.5	638	158	336	211	16:42
7	David Backes D. Backes	254	727	206	460	+65	969	58	53	4	5	26	2	1,650	12.5	4,257	8,561	49.7	2,138	492	353	204	18:15
8	Jaden Schwartz J. Schwartz	231	560	154	385	+74	153	36	44	4	2	21	5	1,243	12.4	274	568	48.2	453	276	382	188	17:42
9	Colton Parayko C. Parayko	225	746	77	302	+63	208	17	27	2	6	20	4	1,536	5.0	0	0		962	1,443	423	472	22:31
10	Doug Weight D. Weight	220	364	75	295	+14	247	28	101	0	3	13	3	804	9.3	2,592	5,238	49.5	242	150	103	181	19:44
11	Keith Tkachuk K. Tkachuk	219	543	208	427	0	677	96	61	1	1	29	6	1,478	14.1	2,355	4,590	51.3	737	130	171	351	17:47
12	Pavol Demitra P. Demitra	207	343	142	349	+75	120	43	77	0	0	28	7	961	14.8	1,550	3,296	47.0	88	83	100	294	19:27
13	T.J. Oshie	200	443	110	310	+71	239	23	68	7	6	20	2	929	11.8	271	634	42.7	625	288	340	136	18:40
14	Kevin Shattenkirk K. Shattenkirk	199	425	59	258	+24	274	32	97	0	3	10	2	921	6.4	1	4	25.0	408	563	188	210	21:17
15	Jordan Kyrou J. Kyrou	189	438	156	345	-26	108	32	56	0	2	19	1	1,162	13.4	29	73	39.7	117	161	219	256	16:28
16	Ryan O'Reilly R. O'Reilly	172	327	97	269	+46	62	22	48	5	3	15	6	729	13.3	3,954	6,958	56.8	104	163	292	113	20:02
17	Chris Pronger C. Pronger	170	293	44	214	+93	385	23	89	1	8	9	2	731	6.0	0	4	0.0	353	567	166	314	28:42
18	Pavel Buchnevich P. Buchnevich	167	315	105	272	+45	147	28	46	4	7	13	3	711	14.8	243	699	34.8	212	108	149	213	19:05
19	Justin Faulk J. Faulk	162	444	51	213	+33	223	9	41	0	4	14	3	927	5.5	0	0		654	665	205	323	22:40
20	Al MacInnis A. MacInnis	159	274	50	209	+67	205	27	88	2	4	16	2	1,002	5.0	2	2	100.0	152	266	129	247	26:38
21	Patrik Berglund P. Berglund	154	694	168	322	+10	242	39	42	5	1	28	3	1,343	12.5	3,160	6,661	47.4	889	269	299	161	15:52
22	Barret Jackman B. Jackman	153	803	28	181	+53	1,026	3	5	2	7	5	1	817	3.4	0	2	0.0	1,024	1,306	265	437	20:23
23	Andy McDonald A. McDonald	140	294	90	230	-19	118	24	61	2	0	12	2	752	12.0	1,132	2,033	55.7	159	107	113	114	18:40
24	Brad Boyes B. Boyes	126	327	106	232	-7	106	33	41	0	0	26	2	799	13.3	508	1,090	46.6	248	82	152	139	17:47
25	Torey Krug T. Krug	124	255	22	146	-23	154	8	51	1	0	4	0	517	4.3	0	0		208	325	80	132	20:54