The Ottawa Senators had the highest goal differential by a team in 2006-07, with a differential of 70 goals.

	TEAM	DIFF	SEASON	GP	W	L	OTL	PTS	PTS%	SOW	SOL	G	GA	PP%	PK%	S/GP	S%	SA/GP	SV%
1	Senators	70	2006-07	82	48	25	9	105	.640	2	6	286	216	17.9	84.5	32.33	10.8	30.23	.913
2	Red Wings	61	2006-07	82	50	19	13	113	.689	2	8	252	191	17.1	84.6	33.79	9.1	24.63	.905
3	Sabres	60	2006-07	82	53	22	7	113	.689	10	4	298	238	17.4	81.3	29.48	12.3	31.00	.906
4	Sharks	59	2006-07	82	51	26	5	107	.652	2	2	256	197	22.4	83.3	28.61	10.9	26.21	.908
5	Predators	59	2006-07	82	51	23	8	110	.671	6	5	266	207	17.4	85.8	27.57	11.8	31.23	.919
6	Ducks	56	2006-07	82	48	20	14	110	.671	4	10	254	198	22.4	85.1	31.49	9.8	27.41	.912
7	Wild	41	2006-07	82	48	26	8	104	.634	10	7	225	184	18.9	86.0	29.65	9.3	28.79	.922
8	Flames	34	2006-07	82	43	29	10	96	.585	3	5	255	221	18.2	80.4	27.34	11.4	30.51	.912
9	Penguins	27	2006-07	82	47	24	11	105	.640	10	6	267	240	20.3	82.1	28.85	11.3	30.85	.905
10	Stars	24	2006-07	82	50	25	7	107	.652	9	4	217	193	18.5	84.4	28.00	9.5	25.40	.907
11	Rangers	22	2006-07	82	42	30	10	94	.573	9	5	233	211	18.5	83.8	31.54	9.0	28.40	.909
12	Canucks	20	2006-07	82	49	26	7	105	.640	5	4	217	197	17.2	86.9	29.33	9.0	29.24	.918
13	Avalanche	20	2006-07	82	44	31	7	95	.579	5	4	267	247	21.1	80.2	31.74	10.3	29.00	.896
14	Devils	13	2006-07	82	49	24	9	107	.652	10	8	206	193	17.7	85.2	28.71	8.8	28.44	.917
15	Islanders	5	2006-07	82	40	30	12	92	.561	8	5	240	235	18.1	81.8	29.99	9.8	32.59	.912
16	Thrashers	-2	2006-07	82	43	28	11	97	.591	7	4	239	241	16.5	79.8	29.73	9.8	31.49	.907
17	Panthers	-4	2006-07	82	35	31	16	86	.524	2	8	245	249	18.1	82.4	33.29	9.0	29.29	.896
18	Hurricanes	-7	2006-07	82	40	34	8	88	.537	0	5	241	248	15.0	84.6	31.21	9.4	28.49	.894
19	Maple Leafs	-8	2006-07	82	40	31	11	91	.555	4	7	254	262	17.7	78.5	32.70	9.5	28.41	.888
20	Canadiens	-12	2006-07	82	42	34	6	90	.549	6	5	239	251	22.8	83.5	29.59	9.9	32.74	.907
21	Lightning	-16	2006-07	82	44	33	5	93	.567	10	2	243	259	18.4	78.4	29.49	10.0	27.24	.884
22	Blues	-40	2006-07	82	34	35	13	81	.494	6	6	208	248	12.1	80.0	26.85	9.4	28.89	.895
23	Capitals	-41	2006-07	82	28	40	14	70	.427	1	11	234	275	16.4	80.2	27.99	10.2	33.34	.899
24	Blue Jackets	-48	2006-07	82	33	42	7	73	.445	5	5	196	244	14.8	81.2	27.72	8.6	28.60	.896
25	Oilers	-53	2006-07	82	32	43	7	71	.433	3	3	192	245	14.2	84.6	26.74	8.8	29.74	.900