Cristiano Ronaldo has a hat trick, 8 goals and an assist in 10 appearances in the Premier League against Big Six opponents since 2009-10.
| NAME | DATE | CLUB | OPP | MIN | G | A | XG | XA | PK | FK | SH | SOT | WOOD | TCH | TCH-BOX | OFF | FOUL | YC | RC | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | C. Ronaldo | 10/24/2021 |  Man United | vs |  Liverpool | 90 | 0 | 0 | 0.59 | 0.03 | 0 | 0 | 4 | 1 | 0 | 38 | 5 | 2 | 1 | 1 | 0 |
| 2 | | C. Ronaldo | 10/30/2021 | Man United | @ |  Tottenham | 71 | 1 | 1 | 0.13 | 0.22 | 0 | 0 | 2 | 1 | 0 | 37 | 3 | 1 | 1 | 0 | 0 |
| 3 | | C. Ronaldo | 11/6/2021 | Man United | vs |  Man City | 90 | 0 | 0 | 0.13 | 0.01 | 0 | 0 | 1 | 1 | 0 | 27 | 1 | 3 | 0 | 1 | 0 |
| 4 | | C. Ronaldo | 11/28/2021 | Man United | @ |  Chelsea | 26 | 0 | 0 | 0.00 | 0.00 | 0 | 0 | 0 | 0 | 0 | 7 | 1 | 0 | 1 | 1 | 0 |
| 5 | | C. Ronaldo | 12/2/2021 | Man United | vs |  Arsenal | 88 | 2 | 0 | 1.54 | 0.06 | 1 | 0 | 6 | 4 | 0 | 38 | 6 | 0 | 2 | 0 | 0 |
| 6 | | C. Ronaldo | 3/12/2022 | Man United | vs | Tottenham | 83 | 3 | 0 | 0.91 | 0.02 | 0 | 0 | 8 | 5 | 0 | 54 | 8 | 0 | 0 | 0 | 0 |
| 7 | | C. Ronaldo | 4/23/2022 | Man United | @ | Arsenal | 90 | 1 | 0 | 0.53 | 0.03 | 0 | 0 | 3 | 1 | 0 | 39 | 6 | 2 | 1 | 1 | 0 |
| 8 | | C. Ronaldo | 4/28/2022 | Man United | vs | Chelsea | 90 | 1 | 0 | 0.37 | 0.01 | 0 | 0 | 3 | 1 | 0 | 60 | 5 | 2 | 1 | 0 | 0 |
| 9 | | C. Ronaldo | 8/22/2022 | Man United | vs | Liverpool | 4 | 0 | 0 | 0.01 | 0.00 | 0 | 0 | 1 | 0 | 0 | 7 | 1 | 0 | 1 | 0 | 0 |
| 10 | | C. Ronaldo | 9/4/2022 | Man United | vs | Arsenal | 32 | 0 | 0 | 0.24 | 0.03 | 0 | 0 | 2 | 0 | 0 | 14 | 3 | 2 | 0 | 0 | 0 |
| Total | 664 | 8 | 1 | 4.45 | 0.41 | 1 | 0 | 30 | 14 | 0 | 321 | 39 | 12 | 8 | 4 | 0 |
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| Team | W | D | L | GD | PTS | |
|---|---|---|---|---|---|---|
| 1 | Liverpool | 5 | 0 | 0 | 6 | 15 |
| 2 | Arsenal | 3 | 1 | 1 | 8 | 10 |
| 3 | Tottenham | 3 | 1 | 1 | 7 | 10 |
| 4 |  Bournemouth | 3 | 1 | 1 | 1 | 10 |
| 5 |  Crystal Palace | 2 | 3 | 0 | 4 | 9 |
| 6 | Chelsea | 2 | 2 | 1 | 5 | 8 |
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