Lionel Messi has tallied the most career goals by a South American in LaLiga, with 474 goals.

	NAME	G	M	MIN	START	G/M	A	G+A	PK	FK	SH	SOT	WOOD	TCH	TCH-BOX	OFF
1	Lionel Messi L. Messi	474	520	42,168	464	0.91	106	580	60
2	Alfredo Di Stéfano A. Di Stéfano	227	329	29,610	329	0.69			17
3	Luis Suárez L. Suárez	178	258	20,285	229	0.69	74	252	14	2	802	389	34	9,765	1,291	304
4	Diego Forlán D. Forlán	128	240	19,269	218	0.53			14
5	Mario Alberto Kempes M. Alberto Kempes	126	222	18,895	218	0.57			26
6	Ronaldo	117	164	13,143	153	0.71			8
7	Waldo Machado W. Machado	115	216	18,953	210	0.53			1
8	Cristhian Stuani C. Stuani	111	327	18,333	181	0.34	8	119	23
9	José Eulogio Gárate J. Eulogio Gárate	110	241	20,822	236	0.46			1
10	Gonzalo Higuaín G. Higuaín	107	190	11,947	132	0.56			3
11	Rivaldo	107	198	16,789	195	0.54			16
12	Cayetano Ré C. Ré	103	265	23,639	264	0.39			2
13	Iván Luis Zamorano I. Luis Zamorano	98	196	16,511	189	0.50			0
14	Rubén Andrés Cano R. Andrés Cano	93	228	19,246	220	0.41			19
15	José Roberto Gama J. Roberto Gama	86	136	11,697	135	0.63			8
16	Jorge Alberto Valdano J. Alberto Valdano	86	228	19,238	217	0.38			3
17	Carlos Manuel Morete C. Manuel Morete	86	166	14,810	166	0.52			8
18	Carlos Martínez Diarte C. Martínez Diarte	85	244	20,846	238	0.35			8
19	Willian José W. José	82	267	16,025	188	0.31	26	108	15
20	Wálter Pandiani W. Pandiani	82	279	15,387	154	0.29			6
21	Evaristo de Macedo E. de Macedo	82	131	11,790	131	0.63			1
22	Juan Ángel Romero J. Ángel Romero	79	185	16,650	185	0.43			14
23	Roberto Juan Martínez R. Juan Martínez	78	252	17,786	183	0.31			1
24	Orlando Ramón Giménez O. Ramón Giménez	76	253	19,206	216	0.30			0
25	Sergio Agüero S. Agüero	74	179	13,481	151	0.41	0	74	1